Abstract: Disclosed herein are vaso-occlusive devices for forming occluding the vasculature of a patient. More particularly, disclosed herein are vaso-occlusive devices having a textured outer surface for promoting tissue in-growth.

Abstract: A stent configured for implantation in a body lumen includes a plurality of radially expandable circumferential segments, and an axially expandable connecting member connecting adjacent circumferential segments of the plurality. The stent has a relaxed, axially contracted configuration in which the connecting member is contracted axially and each circumferential segment is nested with at least one adjacent circumferential segment. The stent also has a delivery, axially expanded configuration in which the connecting member is expanded axially, and an axial distance between adjacent circumferential segments of the plurality is greater than when the stent is in its relaxed configuration.

Abstract: An embolectomy cage having an elongate axis and a circumference comprises a plurality of paired, closely spaced, substantially parallel, elongate members collectively defining a plurality of open cells, wherein individual elongate members of the pairs are connected at nodes located between respective pairs of axially adjacent cells and circumferentially adjacent cells, and wherein at least one elongate member spans each node without forming a connection to another elongate member.

Abstract: An elongate medical device having a longitudinal axis and a surface; and a continuous, helical bi-component fiber wound around at least a portion of the surface of the medical device along its longitudinal axis, wherein the bi-component fiber has a cross-section with a generally flattened side and an inner core encased in a sheath, and wherein the inner core is aligned about the medical device.

Abstract: The present invention is a method for treating aneurysms of various shapes and sizes.

Abstract: A stent configured for implantation in a body lumen includes a plurality of radially expandable circumferential segments, and an axially expandable connecting member connecting adjacent circumferential segments of the plurality. The stent has a relaxed, axially contracted configuration in which the connecting member is contracted axially and each circumferential segment is nested with at least one adjacent circumferential segment. The stent also has a delivery, axially expanded configuration in which the connecting member is expanded axially, and an axial distance between adjacent circumferential segments of the plurality is greater than when the stent is in its relaxed configuration.

Abstract: A stent delivery system having rapid exchange capabilities for delivering a self-expandable stent. The system includes a delivery catheter and a sheath positionable in the lumen of the delivery catheter. The delivery catheter includes an elongate shaft extending distally from a hub assembly. The elongate shaft includes a lumen extending therethrough and a guidewire port providing access to the lumen at a location intermediate the proximal and distal ends of the elongate shaft. The sheath is positionable in the lumen of the delivery catheter such that the sheath extends across the guidewire port to close off the guidewire port to allow a stent to be passed through the sheath from proximal of the guidewire port to distal of the guidewire port.

Abstract: A balloon catheter includes a balloon support member having a hollow axial lumen and open distal end for allowing passage of a guidewire therethrough, a balloon disposed around the balloon support member, and an annular balloon seal disposed proximate to a distal end of the balloon catheter. The seal defines a central passageway for allowing passage therethrough of a guidewire extending out the distal end of the balloon support member, and is configured to form a substantially fluid tight seal around each of a plurality of guidewires having different outer diameters.

Abstract: A balloon catheter includes a balloon support member having a hollow axial lumen and open distal end for allowing passage of a guidewire therethrough, a balloon disposed around the balloon support member, and an annular balloon seal disposed proximate to a distal end of the balloon catheter. The seal defines a central passageway for allowing passage therethrough of a guidewire extending out the distal end of the balloon support member, and is configured to form a substantially fluid tight seal around each of a plurality of guidewires having different outer diameters.

Abstract: A device for removing a blood clot from a lumen of a vessel, the device comprising a pusher and an expandable tubular cage fixedly engaged to the pusher. The tubular cage has a proximal end, a distal end, and a wall extending therebetween. The wall comprises a plurality of bands of cells axially arranged along the tubular cage, wherein one band of cells comprises at least one skiving cell having a cell wall with a proximal portion, a distal portion, and a central portion between the proximal portion and the distal portion. The central portion deforms radially inward in response to a radially applied force to a greater extent than the distal portion.

Abstract: A stent delivery system having rapid exchange capabilities for delivering a self-expandable stent. The system includes a delivery catheter and a sheath positionable in the lumen of the delivery catheter. The delivery catheter includes an elongate shaft extending distally from a hub assembly. The elongate shaft includes a lumen extending therethrough and a guidewire port providing access to the lumen at a location intermediate the proximal and distal ends of the elongate shaft. The sheath is positionable in the lumen of the delivery catheter such that the sheath extends across the guidewire port to close off the guidewire port to allow a stent to be passed through the sheath from proximal of the guidewire port to distal of the guidewire port.

Abstract: A vascular recanalization device for re-establishing blood flow through a vessel lumen. The vascular recanalization device includes an elongate wire and an expandable cage slidably coupled to the elongate wire. The expandable cage includes a proximal collar slidably disposed on the elongate wire and a distal collar slidably disposed on the elongate wire. A central stop is secured to the elongate wire intermediate the proximal collar and the distal collar. A proximal stop is located proximal of the proximal collar of the expandable cage, and a distal stop is located distal of the distal collar of the expandable cage. The proximal collar is slidable along the elongate wire between the proximal stop and the central stop, and the distal collar is slidable along the elongate wire between the central stop and the distal stop.

Abstract: Apparatus and methods for treating a wall of an aneurysm formed in a vessel includes introducing a tubular member into the body lumen until a distal end of the tubular member is located within the aneurysm. A fluid is delivered via a lumen of the tubular member into the aneurysm to at least partially de-endothelialize the wall of the aneurysm, thereby causing an endothelium of the wall to generate fibrous tissue to strengthen the wall of the aneurysm.

Abstract: Apparatus and methods for treating a wall of an aneurysm formed in a vessel includes introducing a tubular member into the body lumen until a distal end of the tubular member is located within the aneurysm. A fluid is delivered via a lumen of the tubular member into the aneurysm to at least partially de-endothelialize the wall of the aneurysm, thereby causing an endothelium of the wall to generate fibrous tissue to strengthen the wall of the aneurysm.

Abstract: Compositions for embolization are disclosed herein. The compositions disclosed can have a matrix-forming component, a solid-aggregate material, and a rheology modifying agent, wherein the matrix-forming component includes at least alkyl cyanoacrylate monomers, a stabilizer, and a plasticizer, and the solid-aggregate material includes at least a radiopacifier. The composition and a method of administering the composition are useful for treating vasculature abnormalities, particularly when the composition solidifies upon contact with an ionic environment, such as blood.

Abstract: The present invention provides an embolic assembly delivery apparatus having superior flexibility characteristics at its distal end, that is, at the point of attachment of the embolic assembly to the delivery apparatus. It also provides a method of using the apparatus to deliver an embolic assembly to a target site in a patient's body.

Abstract: Compositions for embolization are disclosed herein. The compositions disclosed can have a matrix-forming component, a solid-aggregate material, and a rheology modifying agent, wherein the matrix-forming component includes at least alkyl cyanoacrylate monomers, a stabilizer, and a plasticizer, and the solid-aggregate material includes at least a radiopacifier. The composition and a method of administering the composition are useful for treating vasculature abnormalities, particularly when the composition solidifies upon contact with an ionic environment, such as blood.

Abstract: Disclosed herein are vaso-occlusive devices for forming occluding the vasculature of a patient. More particularly, disclosed herein are vaso-occlusive devices having a textured outer surface for promoting tissue in-growth.

Abstract: The present invention provides an embolic assembly delivery apparatus having superior flexibility characteristics at its distal end, that is, at the point of attachment of the embolic assembly to the delivery apparatus. It also provides a method of using the apparatus to deliver an embolic assembly to a target site in a patient's body.