Abstract: Vaso-occlusive devices for occluding a body cavity include an internal element located within a lumen of the device. The internal element may include an active element configured to stiffen the coil in-situ made from a material that can expand to a desired size, thereby inducing a radial stress to the coil to stiffen the occlusive device. Alternatively, the active element is secured to two points on the occlusive device, and is made from a material that contracts, thereby inducing a compression to stiffen the device. The internal element may additionally include an agent carrier that comprises a bioactive material capable of eliciting a biological reaction after the device is placed in-situ. For example, the bioactive material can be a part of a composition of the agent carrier, absorbed by the agent carrier, or coated as a layer on the agent carrier.

Abstract: Described herein are vascular access sheaths having an integrated electrode therein. Also described are assemblies comprising the sheaths as well as methods of making and using the vascular access sheaths.

Abstract: A vaso-occlusive device includes a member that forms a series of at least four successive loops, each loop of the series having a different axis than, and lying in a separate plane from, any other loop of the series. Each plane in which a loop lies forms an angle greater than 30 degrees with any immediately proceeding, and any immediately succeeding, plane.

Abstract: The present invention provides an occlusive composition comprising: a) a poly(2-cyanoacrylate) monomer of the following formula (I): wherein n?2 and R is an organic moiety; and b) a visualization agent. The present invention also provides a method for creating a solid mass in an ionic fluid-containing bodily cavity within a living organism, comprising delivering into the bodily cavity a clinically sufficient amount of an occlusive composition comprising a poly(2-cyanoacrylate) monomer of formula (I) and a visualization agent.

Abstract: A solid embolic material that is capable of filling irregularly shaped and asymmetrical vascular defects in a controlled and predictable manner, without the difficulties associated with delivery of the embolic material through a microcatheter and containment of the embolic material in a defect. A detachable embolic balloon with optional check valve for maintaining liquid in the balloon prior to curing and optional multi-leaflet covering to prevent the balloon from expanding into the native vascular lumen.

Abstract: A method and apparatus for operating a power system is disclosed. A plurality of sensor signals each representative of an operating characteristic of a power system module are received at a common data bus. The sensor signals are received and analyzed at a controller for the presence of an abnormal operating condition, and in response thereto it is determined whether an operational adjustment of the power system module is desirable. In response to the existence of a desirable adjustment condition, the operation of the power system module is automatically adjusted. A sensor of the plurality of sensors is arranged for providing an operating characteristic that is derivable from one or more of the other sensors, which include a different type of sensor, thereby providing redundant system information for determining whether an operational adjustment of the power system module is desirable.

Abstract: The present invention provides an embolic assembly delivery apparatus having superior flexibility characteristics at its distal end, that is, at the point of attachment of the embolic assembly to the delivery apparatus. It also provides a method of using the apparatus to deliver an embolic assembly to a target site in a patient's body.

Abstract: Apparatus and methods for treating a wall of an aneurysm formed in a vessel includes introducing a tubular member into the body lumen until a distal end of the tubular member is located within the aneurysm. A fluid is delivered via a lumen of the tubular member into the aneurysm to at least partially de-endothelialize the wall of the aneurysm, thereby causing an endothelium of the wall to generate fibrous tissue to strengthen the wall of the aneurysm.

Abstract: The present invention is an aneurysm treatment device for treating aneurysms of various shapes and sizes.

Abstract: A solid embolic material that is capable of filling irregularly shaped and asymmetrical vascular defects in a controlled and predictable manner, without the difficulties associated with delivery of the embolic material through a microcatheter and containment of the embolic material in a defect. A detachable embolic balloon with optional check valve for maintaining liquid in the balloon prior to curing and optional multi-leaflet covering to prevent the balloon from expanding into the native vascular lumen.

Abstract: The present invention provides an occlusive composition comprising: a) a poly(2-cyanoacrylate) monomer of the following formula (I): 1

Abstract: The present invention involves a magnetic detachable embolization apparatus and method for embolizing an aneurysm of a blood vessel. The apparatus includes an element adapted to be detachably connected to a distal portion of a catheter for insertion within an aneurysm of a blood vessel, the element being shaped to be retained within the aneurysm, and one or more magnets carried by the element to internally induce a magnetic field from within the aneurysm to control a magnetic field controllable embolic to embolize the aneurysm. The method includes providing a magnetic-field controllable embolic within or adjacent to an aneurysm in a blood vessel, and internally inducing a magnetic field from within the aneurysm to control the magnetic-field controllable embolic to embolize the aneurysm.

Abstract: Compositions for embolization are disclosed herein. The compositions disclosed can have a matrix-forming component, a solid-aggregate material, and a rheology modifying agent, wherein the matrix-forming component includes at least alkyl cyanoacrylate monomers, a stabilizer, and a plasticizer, and the solid-aggregate material includes at least a radiopacifier. The composition and a method of administering the composition are useful for treating vasculature abnormalities, particularly when the composition solidifies upon contact with an ionic environment, such as blood.

Abstract: The present invention is an aneurysm treatment device for treating aneurysms of various shapes and sizes.

Abstract: The present invention involves a magnetic detachable embolization apparatus and method for embolizing an aneurysm of a blood vessel. The apparatus includes an element adapted to be detachably connected to a distal portion of a catheter for insertion within an aneurysm of a blood vessel, the element being shaped to be retained within the aneurysm, and one or more magnets carried by the element to internally induce a magnetic field from within the aneurysm to control a magnetic field controllable embolic to embolize the aneurysm. The method includes providing a magnetic-field controllable embolic within or adjacent to an aneurysm in a blood vessel, and internally inducing a magnetic field from within the aneurysm to control the magnetic-field controllable embolic to embolize the aneurysm.

Abstract: Circuitry for affording access to a common passive bus by a plurality of computer devices connected to the bus. Each of the devices is provided with the circuitry, which operates in three sequential phases: a bus request phase, an address phase and a data transfer phase. Circuitry interconnecting the bus connections for permitting a device to initiate the bus request phase only if all devices superior to it are not in the bus request phase thereby establishing a priority ranking among the devices. The circuitry also includes a call back system wherein if a given device is unready to receive data when addressed by a source device, such device will, when it is ready, call back the source device that was previously and unsuccessfully attempting to transfer data to it.