Abstract: A method for assembling a razor handle is provided. The method includes installing a rod into a first shell of a body of a razor handle, installing an attachment end of a head onto a front end of the first shell, installing a clip member onto a rear end of the first shell, positioning a second shell adjacent to the first shell, compressing the first shell and the second shell together, and covering the first and second shell with a cover layer. The clip member includes retention features to facilitate coupling to the first and second shells. The cover layer can entirely surround the first and second shells, can be overmolded on both shells, and can be formed of thermoplastic elastomer with a durometer value of between about 15 and about 20. The thermoplastic elastomer is substantially translucent or less opaque than the first and second shell.

Abstract: The invention is directed to a particle containing at least a volatile substance comprising a core comprising at least one matrix material and the at least one volatile substance and at least one coating layer, whereby a first coating layer is a non-confluent layer comprising at least a carrier material, whereby optionally the non-confluent layer contains at least one hydrophobic substance, and optionally the particle is surrounded by at least one confluent layer and/or further non-confluent layer(s) as well as to a process for producing the same.

Abstract: A link assembly (3) and system (203) including a first link portion (7, 207) and a second link portion (9, 209). The first link portion (7, 207) includes a bulbous end (13). The second link portion (9, 209 a socket (15). To link adjacent link assemblies (3) or the first link portion (7, 207) to the second link portion (9, 209), the bulbous end (13) is received in the socket (15). In one example, the link assembly (3) is part of an agricultural ground engaging chain (1) having harrow member portions (5). In other examples, the link assembly and system (203) are used to link first element (204) and second elements (206) to one another. This may be used to join or anchor vehicles, structures and the like.

Abstract: A cooled gas turbine engine component comprises a wall which has a plurality of effusion cooling apertures extending there-through from a first surface to a second surface. The apertures are arranged at an angle to the second surface and each aperture has an inlet in the first surface and an outlet in the second surface. Each aperture has a metering portion and a diffusing portion arranged in flow series and each metering portion is elongate and the width is greater than the length of the metering portion. Each diffusing portion increases in dimension in the length from the metering portion to the outlet. Each outlet has a rectangular shape in the second surface of the wall. Each inlet has an elongate shape in the first surface of the wall and the inlet in the wall is arranged substantially diagonally with respect to the outlet in the wall.

Abstract: A smart part comprising: a body, manufactured by a three-dimensional (3D) additive manufacturing (AM) process, having high-stress and low-stress sections, wherein when the smart part is in operational use the high-stress section is subjected to higher stress than the low-stress section; and wherein the body comprises a void having a predefined geometry intentionally created within the high-stress section of the body during the AM process, such that the void is completely embedded within the body and is configured to provide quality assurance information.

Abstract: There are provided methods for preparing lithium carbonate. For example, such methods can comprise reacting an aqueous composition comprising lithium hydroxide with CO2 by sparging the CO2 the said composition, thereby obtaining a precipitate comprising the lithium carbonate. The methods can also comprise inserting at least a portion of the precipitate into a clarifier and obtaining a supernatant comprising lithium bicarbonate and a solid comprising the lithium carbonate, separating the solid from the supernatant; and heating the supernatant at a desired temperature so as to at least partially convert the lithium bicarbonate into lithium carbonate.

Abstract: An apparatus for testing a coefficient of friction of an article is provided. The apparatus includes a base, a ramp, and an actuator. The ramp includes a first rail and a second rail that are spaced apart by a first distance. The first and second rails cooperate to define a first travel path for the article. The actuator is coupled with the base and is operably coupled with the ramp to facilitate selective pivoting of the ramp between a first angular position and a second angular position.

Abstract: The present invention relates to bioluminescence resonance energy transfer sensor molecules having the structure R1-L-R2—B or B—R2-L-R1, wherein R1 is a bioluminescent protein, L is a linking element, R2 is a non-protein acceptor domain and B is a blocking group, and wherein R2 bound to B comprises a hydrolysable bond which produces a change in BRET when hydrolysed. The invention also discloses a method of detecting a hydrolase by contacting a sample with a molecule B—R2, then contacting with a compound R1-L or L-R1 under conditions to cause attaching of R2 to L, and detecting a change in the BRET ratio. Specifically exemplified sensors comprise luciferase and fluorescein diacetate, which is hydrolysed by an esterase. The invention also discloses luciferase enzymes derived from RLuc8 by removing cysteine residues.

Abstract: An immune gene expression signature is associated with favorable clinical features in Treg-enriched tumor samples and can be used to predict immunogenicity of a tumor, overall survival, and/or chemosensitivity.

Abstract: A waistband with retractable display panel apparatus having a waistband, a display panel frame and a display panel. The waistband includes a first strap and a buckle. The first strap including a plurality of notches, wherein one of the plurality of notches connects to the buckle to allow the waistband to be worn around a wearer's waist. The display panel frame includes a second strap and a first attachment mechanism. The second strap includes a plurality of notches. The first attachment mechanism connects the second strap to the first strap, by attaching one or more of the plurality of notches located along a left side of the second strap to one or more of the plurality of notches located on a left side of the first strap and by attaching one or more of the plurality of notches located along a right side of the second strap to one or more of the plurality of notches located on a right side of the first strap.

Abstract: A method is provided for reducing a duration of an inactivate step of a decontamination process of contents within a chamber of a container. The method includes at least one of directing air in contact with a catalyst to reduce a level of hydrogen peroxide (H2O2) in the air during the inactivate step and/or altering a temperature of air within the chamber during the inactivate step. A system is also provided for performing one or more steps of the method. The system includes the container defining the chamber; the catalyst; a component configured to direct air through the catalyst; and a processor configured to cause components of the system to perform one or more steps of the method.

Abstract: An apparatus for testing a coefficient of friction of an article is provided. The apparatus includes a base, a ramp, and an actuator. The ramp includes a first rail and a second rail that are spaced apart by a first distance. The first and second rails cooperate to define a first travel path for the article. The actuator is coupled with the base and is operably coupled with the ramp to facilitate selective pivoting of the ramp between a first angular position and a second angular position.

Abstract: One embodiment of a humidifier designed to supplement humidity for the purpose of maintaining the moisture content of a wooden instrument such as a guitar. The humidifier comprises of an absorbent material, contained within an expandable outer shell, sealed at both ends. The shell is made from a non-permeable material but is constructed to be permeable. The humidifier is hydrated by submerging it in water, resulting in the absorption of liquid, causing expansion of the absorbent core and consequently expansion of the outer shell. Once hydrated, the outer shell is dried, and then, in the case of a hollow bodied instrument, is placed inside the body, or alternatively, and in the case of a solid bodied instrument, is placed in proximity to the instrument in a case or other enclosure. The shell allows the efficient egress of water vapor while isolating the instrument from liquid sequestered by the absorbent within.

Abstract: There are provided methods for preparing lithium carbonate. For example, such methods can comprise reacting an aqueous composition comprising lithium hydroxide with CO2 by sparging the CO2 the said composition, thereby obtaining a precipitate comprising the lithium carbonate. The methods can also comprise inserting at least a portion of the precipitate into a clarifier and obtaining a supernatant comprising lithium bicarbonate and a solid comprising the lithium carbonate, separating the solid from the supernatant; and heating the supernatant at a desired temperature so as to at least partially convert the lithium bicarbonate into lithium carbonate.

Abstract: The present invention relates to sensors and methods for detecting carbohydrates, such as lactose, in a sample. The sensors and methods may also be used to determine the amount of carbohydrate in the sample.

Abstract: A system and method are described for receiving biological process input data from a biological process input data source and transforming the biological process input data into curated data, which may be in a flattened or normalized data space. As an example, a curation server is disclosed with the ability to transform biological process input data from the scientific literature such that the data can be mapped to patient-specific genomic data.

Abstract: Systems and methods are presented that allow for selection of tumor neoepitopes that are then used to generate a recombinant polytope that is optimized for proper trafficking and processing. In preferred methods, the polytope is encoded in a viral expression system that is used as a therapeutic agent.

Abstract: A waistband with retractable display panel apparatus having a waistband, a display panel frame and a display panel. The waistband includes a first strap and a buckle. The first strap including a plurality of notches, wherein one of the plurality of notches connects to the buckle to allow the waistband to be worn around a wearer's waist. The display panel frame includes a second strap and a first attachment mechanism. The second strap includes a plurality of notches. The first attachment mechanism connects the second strap to the first strap, by attaching one or more of the plurality of notches located along a left side of the second strap to one or more of the plurality of notches located on a left side of the first strap and by attaching one or more of the plurality of notches located along a right side of the second strap to one or more of the plurality of notches located on a right side of the first strap.

Abstract: Contemplated systems and methods allow for computational genomic analysis using paired-end sequence analysis and split read refinement to thereby identify high-confidence breakpoints associated with high copy numbers and orientation of rearrangements, which is then the basis for full reconstruction of double minutes (DM). In especially preferred aspects, the DM will also include an oncogene or tumor suppressor gene, and/or may be found in blood or blood derived fluids.

Abstract: A method is provided for vaporized hydrogen peroxide cleaning of a chamber. The method includes altering a temperature of air in the chamber from an initial temperature to a sterilization temperature over a first time period. The method also includes injecting vaporized hydrogen peroxide into air in the chamber to alter a relative humidity of hydrogen peroxide vapor in the chamber to a sterilization level over the first time period. The method also includes maintaining the temperature at the sterilization temperature and the relative humidity at the sterilization level over a second time period. The method also includes reducing the relative humidity from the sterilization level to a safe level over a third time period. In one embodiment, the method is provided for vaporized hydrogen peroxide cleaning of an interior chamber of an incubation container. In other embodiments, the incubation chamber featured in the method is provided.