Patents by Inventor Stephen Charles

Stephen Charles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and Method of a Supply Chain Retail Process Manager
    Publication number: 20220253778
    Abstract: A system and method are disclosed for analyzing the maturity of one or more supply chain entities according to competencies of an omni-channel retailer. The one or more supply chain entities including a retail manager that assesses the one or more supply chain entities according to one or more competencies and determines one or more maturity gaps associated with the one or more competencies. The retail manger further identifies one or more transition projects that fill the one or more maturity gaps and roadmaps one or more transition activities that generate the one or more identified transition projects. The one or more supply chain entities further adjusts an inventory of one or more products at least partially based on the one or more roadmapped transition activities.
    Type: Application
    Filed: May 2, 2022
    Publication date: August 11, 2022
    Inventors: Stephen Charles Davis, David Thomas Kudas, Donald Patrick Brenchley
  • Safety packaging channel
    Patent number: 11407569
    Abstract: A packaged bundle using a special designed packaging channel for dunnage is disclosed. The packaging channel dunnage has a channel with hemmed edges and swedged ends exhibiting a two-curved profile to provide a more secure bundle and improved safety during transport and handling.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: August 9, 2022
    Assignee: Telling Industries, LLC
    Inventors: Charles Andrew Haba, William J. Gibbs, Stephen Charles Linch
  • Methods and systems for detecting an analyte or classifying a sample
    Patent number: 11385234
    Abstract: The present invention relates to methods and systems for detecting one or more analytes in a sample and/or for classifying a sample. In particular, the present invention relates to methods and systems which can be used to detect the analytes in real time and which rely on flowing through a microfluidic device one or more types of sensor molecule each comprising a domain that binds one or more analytes, a chemiluminescent donor domain and an acceptor domain, wherein the separation and relative orientation of the chemiluminescent donor domain and the acceptor domain, in the presence and/or the absence of analyte, is within ±50% of the Forster distance.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: July 12, 2022
    Assignee: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Stephen Charles Trowell, Helen Dacres, Nam Cao Hoai Le, Murat Gel, Yonggang Zhu, Nan Wu
  • Systems, methods, and compositions for viral-associated tumors
    Patent number: 11361844
    Abstract: Contemplated systems and methods employ chimeric reference sequences that include a plurality of viral genome sequences to identify/quantify integration and co-amplification events. Most typically, the viral genome sequences are organized in the chimeric reference sequences as single chromosomes and the chimeric reference sequences are in BAM format.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: June 14, 2022
    Assignee: Five3 Genomics, LLC
    Inventors: John Zachary Sanborn, Charles Joseph Vaske, Stephen Charles Benz, Shahrooz Rabizadeh, Nicole Hensley, Patrick Soon-Shiong
  • High-throughput identification of patient-specific neoepitopes as therapeutic targets for cancer immunotherapies
    Patent number: 11361841
    Abstract: Systems and methods are presented that allow for selection of tumor neoepitopes that are filtered for various criteria. In particularly contemplated aspects, filtering includes a step in which the mutation leading to the neoepitope is ascertained as being located in a cancer driver gene.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: June 14, 2022
    Assignee: Nantomics LLC
    Inventors: Andrew Nguyen, John Zachary Sanborn, Stephen Charles Benz, Kayvan Niazi, Shahrooz Rabizadeh, Patrick Soon-Shiong, Charles Joseph Vaske
  • IMMUNOME PROFILING FOR ENGINEERING WHITE BLOOD CELLS
    Publication number: 20220170099
    Abstract: Single cell analysis from tumor tissue comprising tumor cells and immune competent cells and from peripheral white blood cells are used to obtain an immunome signature, and to gain information about the TCR repertoire. Such information is then employed to generate recombinant and patient specific therapeutic cells, including T cells (including T effector memory, T memory stem, naïve T, T central memory, CD8+ T, and CD4+ T cells), NK cells (cord-blood derived or PBMC derived or NK92), NKT cells, and dendritic cells.
    Type: Application
    Filed: July 24, 2020
    Publication date: June 2, 2022
    Inventors: Shahrooz Rabizadeh, Patrick Soon-Shiong, Peter Sieling, Stephen Charles Benz, Andrew Nguyen
  • TUMOR ANTIGENICITY PROCESSING AND PRESENTATION
    Publication number: 20220165353
    Abstract: Methods for targeting a tumor antigen for immunotherapy based on HLA allele type and the mutations present in the tumor antigen are presented. A patient's HLA allele type and a tumor antigen derived from a mutation in cancer driver gene can be matched with a majority allele type having a minimum affinity to the same tumor antigen or with those of a plurality of patients with a history of cancer treatment. Upon matching, a cancer treatment against the tumor antigen can be selected and administered to the patient to achieve a desired effect.
    Type: Application
    Filed: February 3, 2022
    Publication date: May 26, 2022
    Inventors: Andrew Nguyen, John Zachary Sanborn, Charles Joseph Vaske, Shahrooz Rabizadeh, Kayvan Niazi, Patrick Soon-Shiong, Stephen Charles Benz
  • Agricultural ground engaging chain and link system
    Patent number: 11337353
    Abstract: A link assembly (3) and system (203) including a first link portion (7, 207) and a second link portion (9, 209). The first link portion (7, 207) includes a bulbous end (13). The second link portion (9, 209 a socket (15). To link adjacent link assemblies (3) or the first link portion (7, 207) to the second link portion (9, 209), the bulbous end (13) is received in the socket (15). In one example, the link assembly (3) is part of an agricultural ground engaging chain (1) having harrow member portions (5). In other examples, the link assembly and system (203) are used to link first element (204) and second elements (206) to one another. This may be used to join or anchor vehicles, structures and the like.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: May 24, 2022
    Assignee: IRON GRIP HOLDINGS PTY LIMITED
    Inventors: Stephen Charles Ainge, Seyed Ali Heydarshahy
  • System and method of a supply chain retail process manager
    Patent number: 11321649
    Abstract: A system and method are disclosed for analyzing the maturity of one or more supply chain entities according to competencies of an omni-channel retailer. The one or more supply chain entities including a retail manager that assesses the one or more supply chain entities according to one or more competencies and determines one or more maturity gaps associated with the one or more competencies. The retail manger further identifies one or more transition projects that fill the one or more maturity gaps and roadmaps one or more transition activities that generate the one or more identified transition projects. The one or more supply chain entities further adjusts an inventory of one or more products at least partially based on the one or more roadmapped transition activities.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: May 3, 2022
    Assignee: Blue Yonder Group, Inc.
    Inventors: Stephen Charles Davis, David Thomas Kudas, Donald Patrick Brenchley
  • Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation
    Publication number: 20220096643
    Abstract: The present invention relates to polymeric reagents and conjugates thereof, methods for synthesizing the polymeric reagents and conjugates, pharmaceutical compositions comprising the conjugates and methods of using the polymer conjugates including therapeutic methods where conjugates are administered to patients.
    Type: Application
    Filed: December 16, 2021
    Publication date: March 31, 2022
    Inventor: Stephen A. Charles
  • Handle for a razor
    Patent number: 11285630
    Abstract: A razor handle for a razor cartridge is provided. The handle comprises a head, a body, a cover layer, and a clip member. The head has a cartridge engaging end and an attachment end. The body has a front end and a rear end and comprises a first shell and a second shell that are releasably coupled together. The front end is coupled with the attachment end. The cover layer at least partially surrounds the body. The clip member is coupled with the first shell and the second shell at the rear end of the body such that the first and second shells are held together at least partially by the clip member. The clip member has a plurality of features which are coupled to a plurality of features on the body. These are retention features such as recesses or projections.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: March 29, 2022
    Assignee: The Gillette Company LLC
    Inventors: Hong Lu, Stephen Charles Witkus, Alexander Stephen Forti, Huibin Gong
  • OPTIMIZED ONCOLYTIC VIRUSES AND USES THEREOF
    Publication number: 20220088098
    Abstract: Methods of inhibiting or reducing tumor growth are disclosed. A composition containing at least one selected oncolytic virus is administered within a tumor of a patient. The virus kills cancerous cells and induces a systemic and lasting anti-tumor immunity that is also compatible with other cancer treatments. Also disclosed are methods of creating synthetic viruses for targeting cancerous tumors.
    Type: Application
    Filed: December 6, 2021
    Publication date: March 24, 2022
    Inventors: Peter M. Chumakov, Anastasia V. Lipatova, Stepan P. Chumakov, Natalia D. Tararova, Stephen A. Charles, Anton A. Komar
  • OPTIMIZED ONCOLYTIC VIRUSES AND USES THEREOF
    Publication number: 20220088097
    Abstract: Methods of inhibiting or reducing tumor growth are disclosed. A composition containing at least one selected oncolytic virus is administered within a tumor of a patient. The virus kills cancerous cells and induces a systemic and lasting anti-tumor immunity that is also compatible with other cancer treatments. Also disclosed are methods of creating synthetic viruses for targeting cancerous tumors.
    Type: Application
    Filed: December 6, 2021
    Publication date: March 24, 2022
    Inventors: Peter M. Chumakov, Anastasia V. Lipatova, Stepan P. Chumakov, Natalia D. Tararova, Stephen A. Charles, Anton A. Komar
  • Tumor antigenicity processing and presentation
    Patent number: 11276479
    Abstract: Methods for targeting a tumor antigen for immunotherapy based on HLA allele type and the mutations present in the tumor antigen are presented. A patient's HLA allele type and a tumor antigen derived from a mutation in cancer driver gene can be matched with a majority allele type having a minimum affinity to the same tumor antigen or with those of a plurality of patients with a history of cancer treatment. Upon matching, a cancer treatment against the tumor antigen can be selected and administered to the patient to achieve a desired effect.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: March 15, 2022
    Assignees: Nantomics, LLC, Nant Holdings IP, LLC
    Inventors: Andrew Nguyen, John Zachary Sanborn, Charles Joseph Vaske, Shahrooz Rabizadeh, Kayvan Niazi, Patrick Soon-Shiong, Stephen Charles Benz
  • Optimized oncolytic viruses and uses thereof
    Patent number: 11253558
    Abstract: Methods of inhibiting or reducing tumor growth are disclosed. A composition containing at least one selected oncolytic virus is administered within a tumor of a patient. The virus kills cancerous cells and induces a systemic and lasting anti-tumor immunity that is also compatible with other cancer treatments. Also disclosed are methods of creating synthetic viruses for targeting cancerous tumors.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: February 22, 2022
    Inventors: Peter M. Chumakov, Anastasia V. Lipatova, Stepan P. Chumakov, Natalia D. Tararova, Stephen A. Charles, Anton A. Komar
  • Processes for preparing lithium carbonate
    Patent number: 11254582
    Abstract: There are provided methods for preparing lithium carbonate. For example, such methods can comprise reacting an aqueous composition comprising lithium hydroxide with CO2 by sparging the CO2 the said composition, thereby obtaining a precipitate comprising the lithium carbonate. The methods can also comprise inserting at least a portion of the precipitate into a clarifier and obtaining a supernatant comprising lithium bicarbonate and a solid comprising the lithium carbonate, separating the solid from the supernatant; and heating the supernatant at a desired temperature so as to at least partially convert the lithium bicarbonate into lithium carbonate.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: February 22, 2022
    Assignee: NEMASKA LITHIUM INC.
    Inventors: Guy Bourassa, Gary Pearse, Stephen Charles Mackie, Mykolas Gladkovas
  • OXYGEN REDUCTION REACTION CATALYST
    Publication number: 20220029172
    Abstract: A method for the manufacture of an oxygen reduction reaction (ORR) catalyst, the method comprising; providing a metal organic framework (MOF) material having a specific internal pore volume of 0.7 cm3g?1 or greater; providing a source of iron and/or cobalt; pyrolysing the MOF material together with the source of iron and/or cobalt to form the catalyst, wherein the MOF material comprises nitrogen and/or the MOF material is pyrolysed together with a source of nitrogen and the source of iron and/or cobalt is disclosed.
    Type: Application
    Filed: October 7, 2021
    Publication date: January 27, 2022
    Inventors: Marie Josephe Vanessa ARMEL, Stephen Charles BENNETT, Frederic Christophe JAQUEN, Deborah JONES, Sheena HINDOCHA, Fabrice SALLES
  • Healthcare Object Recognition, Systems And Methods
    Publication number: 20220028508
    Abstract: Healthcare object (HCO) discriminator systems and methods are presented. Systems can obtain a digital representation of a scene via a sensor interface. An HCO discriminator platform analyzes the digital representation to discriminate objects within the scene as being associated with a type of HCO or as being unrelated to a type of HCO. Once the HCO recognition platform determines that a type of HCO is relevant, it instantiates an actual HCO. The HCO can be routed to one or more destinations based on routing rules generated from a template or based on the manner in which the objects in the scene were discriminated.
    Type: Application
    Filed: October 5, 2021
    Publication date: January 27, 2022
    Inventors: Patrick SOON-SHIONG, John Zachary SANBORN, Stephen Charles BENZ, Charles Joseph VASKE
  • INTRALUMINAL MEDICAL IMAGING INTERFACE DEVICES AND SYSTEMS
    Publication number: 20220008036
    Abstract: An intraluminal medical imaging interface device includes an arm assembly comprising one or more longitudinal members and one or more joints coupled to the one or more longitudinal members, and a head assembly coupled to a distal portion of the arm assembly and comprising a proximal portion coupled to the distal portion of the arm assembly and a distal portion. The distal portion of the head assembly includes a mechanical coupling and an electrical coupling configured to separably connect to an intraluminal imaging catheter and to transmit electrical signals between a console and the intraluminal imaging catheter. The arm assembly is configured to couple to a surface to maintain the head assembly at a first position and an orientation with respect to a patient without continued support by an operator. Associated devices, systems, and methods are also provided.
    Type: Application
    Filed: April 25, 2019
    Publication date: January 13, 2022
    Inventors: Ashen GULSEN, Volker Barnhart VERSCHOOR, Andrew MITCHELL, Godefridus Antonius HARKS, Stephen Charles DAVIES, Dirk Jan Nelly VANANDEROYE
  • Hypoxic NK cells and methods therefor
    Patent number: 11221328
    Abstract: Detection of under-expression of selected genes in NK cells is used to confirm a hypoxic tumor microenvironment that is ordinarily suppressive with respect to ADCC and cytotoxic cell killing of NK cells. Most notably, while hypoxia is known to upregulate HIF-1? and genes under the control of HIF-1?, hypoxia in a tumor microenvironment led to under-expression of selected genes, including HIF-1?. Thus, gene expression analysis of certain genes on NK cells can be used to detect conditions in a tumor that would indicate use of haNK cells.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: January 11, 2022
    Assignee: NantCell, Inc.
    Inventors: Patrick Soon-Shiong, Shahrooz Rabizadeh, Kayvan Niazi, Stephen Charles Benz, Laurent H. Boissel, Hans Klingemann, Barry J. Simon