Patents by Inventor Stephen E. Webber

Stephen E. Webber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BRIDGED POLYCYCLIC COMPOUNDS
    Publication number: 20120321590
    Abstract: The invention is directed to amides of bicyclic amine compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: April 5, 2012
    Publication date: December 20, 2012
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Stephen E. Webber, Chinh V. Tran, Alan X. Xiang, Douglas E. Murphy
  • DEUTERATED 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS
    Publication number: 20120283251
    Abstract: The invention is directed to deuterated 5,6-dihydro-1H-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: October 27, 2010
    Publication date: November 8, 2012
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventor: Stephen E. Webber
  • 3,5-DISUBSTITUTED AND 3,5,7-TRISUBSTITUTED-3H-OXAZOLO AND 3H-THIAZOLO[4,5-D]PYRIMIDIN-2-ONE COMPOUNDS AND PRODRUGS THEREOF
    Publication number: 20120121541
    Abstract: The invention is directed to 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and pharmaceutical compositions containing them, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds and prodrugs.
    Type: Application
    Filed: January 13, 2012
    Publication date: May 17, 2012
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Stephen E. Webber, Gregory J. Haley, Joseph R. Lennox, Alan X. Xiang, Erik J. Rueden
  • [1,2,4]THIADIAZIN-3-YL ACETIC ACID COMPOUND[[S]] AND METHODS OF MAKING THE ACETIC ACID COMPOUND
    Publication number: 20120116077
    Abstract: The invention is directed to [1,2,4]thiadiazine 1,1-dioxide compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: January 13, 2012
    Publication date: May 10, 2012
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Frank Ruebsam, Peter Dragovich, Stephen E. Webber, Douglas E. Murphy, Chinh V. Tran
  • 5,6-dihydro-1H-pyridin-2-one compounds
    Patent number: 8129368
    Abstract: The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds of formula: wherein R is C1-C6 alkyl or (Aryl)CH2-,and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: March 6, 2012
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Frank Ruebsam, Chinh V Tran, Douglas E. Murphy, Peggy A. Thompson, Peter Dragovich, Stephen E. Webber
  • [1,2,4]thiadiazine 1,1-dioxide compounds
    Patent number: 8097613
    Abstract: The invention is directed to [1,2,4]thiadiazine 1,1-dioxide compounds of formula I wherein A is B is and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: January 17, 2012
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Frank Ruebsam, Peter Dragovich, Stephen E. Webber, Douglas Eric Murphy, Chinh Viet Tran
  • 3,5-disubstituted and 3,5,7-trisubstituted-3-oxazolo and 3-thiazolo[4,5-]pyrimidin-2-one compounds and prodrugs thereof
    Patent number: 8097718
    Abstract: The invention is directed to 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and pharmaceutical compositions containing them, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds and prodrugs.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: January 17, 2012
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Stephen E. Webber, Gregory J. Haley, Joseph R. Lennox, Alan X. Xiang, Erik J. Rueden
  • 3,5-DISUBSTITUTED AND 3,5,7-TRISUBSTITUTED-3H-OXAZOLO AND 3H-THIAZOLO[4,5-d]PYRIMIDIN-2-ONE COMPOUNDS AND PRODRUGS THEREOF
    Publication number: 20110275589
    Abstract: The invention is directed to 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and pharmaceutical compositions containing them, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds and prodrugs.
    Type: Application
    Filed: July 1, 2009
    Publication date: November 10, 2011
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Stephen E. Webber, Gregory J. Haley, Joseph R. Lennox, Alan X. Xiang, Erik J. Rueden
  • 3-?-D-ribofuranosylthiazolo[4-5-d]pyrimidine nucleosides and uses thereof
    Patent number: 7943759
    Abstract: The invention is directed to 3-?-D-ribofuranosylthiazolo[4,5-d]pyrimidine nucleosides and pharmaceutical compositions containing such compounds that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and compositions, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: May 17, 2011
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Devron R. Averett, Stephen E. Webber, Joseph R. Lennox, Erik J. Rueden, David Louis Clark, Alan Xin Xiang
  • Pyrro[1,2-]pyridazinone intermediates
    Patent number: 7842838
    Abstract: The invention is directed to pyrro[1,2-b]pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Grant
    Filed: August 21, 2009
    Date of Patent: November 30, 2010
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Stephen E. Webber, Frank Ruebsam, Martin Tran, Peter Dragovich, Liansheng Li, Douglas Eric Murphy, David Kucera, Zhongxiang Sun, Chinh Viet Tran
  • 3-ß-D-RIBOFURANOSYLTHIAZOLO[4-5-d]PYRIMIDINE NUCLEOSIDES AND USES THEREOF
    Publication number: 20100261667
    Abstract: The invention is directed to 3-?-D-ribofuranosylthiazolo[4,5-d]pyrimidine nucleosides and pharmaceutical compositions containing such compounds that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and compositions, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds.
    Type: Application
    Filed: June 25, 2010
    Publication date: October 14, 2010
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Devron R. Averett, Stephen E. Webber, Joseph R. Lennox, Erik J. Rueden, David Louis Clark, Alan X. Xiang
  • Process for the preparation of 5-amino-3H-thiazolo[4,5-d]pyrimidin-2-one
    Patent number: 7781581
    Abstract: The present invention relates to a process for the preparation of 5-amino-3H-thiazolo[4,5-d]pyrimidin-2-one which is a useful intermediate in the preparation of certain thiazolo[4,5-d]pyrimidine nucleosides. The process comprises halogenating 2,4-diaminopyrimidine to form 2,4-diamino-5-halo-pyrimidine and then cyclocondensing the 2,4-diamino-5-halo-pyrimidine to form 5-amino-3H-thiazolo[4,5-d]pyrimidin-2-thione. The 5-amino-3H-thiazolo[4,5-d]pyrimidin-2-thione is then oxidized to afford the 5-amino-3H-thiazolo[4,5-d]pyrimidin-2-one.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: August 24, 2010
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Tingman Wang, John S. Ng, Stephen E. Webber
  • 3-?-D-ribofuranosylthiazolo[4,5-]pyrimidine nucleosides and uses thereof
    Patent number: 7745415
    Abstract: The invention is directed to 3-?-D-ribofuranosylthiazolo[4,5-d]pyrimidine nucleosides and pharmaceutical compositions containing such compounds that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and compositions, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds.
    Type: Grant
    Filed: January 17, 2008
    Date of Patent: June 29, 2010
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Devron R. Averett, Stephen E. Webber, Joseph R. Lennox, Erik J. Rueden
  • 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS
    Publication number: 20100119481
    Abstract: The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: October 9, 2009
    Publication date: May 13, 2010
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Frank Ruebsam, Chinh V. Tran, Douglas E. Murphy, Peggy A. Thompson, Peter Dragovich, Stephen E. Webber
  • Prodrugs of 5-amino-3-(3?-deoxy-?-D-ribofuranosyl)-thiazolo[4,5-]pyrimidin-2,7-dione
    Patent number: 7709448
    Abstract: The invention is directed to 5-amino-3-(3?-deoxy-?-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione prodrugs, whose metabolized parent compound has immunomodulatory activity. The invention also relates to the therapeutic use of such prodrugs and pharmaceutical compositions thereof in treating disease states associated with abnormal cell growth, such as cancer.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: May 4, 2010
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Gregory J. Haley, Joseph R. Lennox, Alan X. Xiang, Stephen E. Webber
  • PYRRO[1,2-b]PYRIDAZINONE COMPOUNDS
    Publication number: 20090312570
    Abstract: The invention is directed to pyrro[1,2-b]pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: August 21, 2009
    Publication date: December 17, 2009
    Applicant: Anadys Pharmaceuticals, Inc
    Inventors: Stephen E. Webber, Frank Ruebsam, Martin Tran, Peter Dragovich, Liansheng Li, Douglas E. Murphy, David Kucera, Zhongxiang Sun, Chinh V. Tran
  • [1,2,4]THIADIAZINE 1,1-DIOXIDE COMPOUNDS
    Publication number: 20090306057
    Abstract: The invention is directed to [1,2,4]thiadiazine 1,1-dioxide compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: June 9, 2009
    Publication date: December 10, 2009
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Frank Ruebsam, Peter Dragovich, Stephen E. Webber, Douglas E. Murphy, Chinh V. Tran
  • Pyrro[1,2-]pyridazinone compounds
    Patent number: 7582754
    Abstract: The invention is directed to pyrro[1,2-b]pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: September 1, 2009
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Stephen E. Webber, Frank Ruebsam, Martin Tran, Peter Dragovich, Liansheng Li, Douglas Eric Murphy, David Kucera, Zhongxiang Sun, Chinh Viet Tran
  • 3,5-Disubsitituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof
    Patent number: 7560544
    Abstract: The invention is directed to 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and pharmaceutical compositions containing them, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds and prodrugs.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: July 14, 2009
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Stephen E. Webber, Gregory J. Haley, Joseph R. Lennox, Alan X. Xiang, Erik J. Rueden
  • Carbonate and carbamate prodrugs of thiazolo[4,5-]pyrimidines
    Patent number: 7528115
    Abstract: The invention is directed to carbonate and carbamate prodrugs of thiazolo[4,5-d]pyrimidine compounds, whose metabolized parent compound has immunomodulatory activity. The invention also relates to the therapeutic use of such prodrugs and pharmaceutical compositions thereof in treating disease states associated with abnormal cell growth, such as cancer.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: May 5, 2009
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Gregory J. Haley, Joseph R. Lennox, Alan X. Xiang, Stephen E. Webber