Patents by Inventor Stephen Frederick Moss

Stephen Frederick Moss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS
    Publication number: 20230340026
    Abstract: The present invention provides a compound of formula (I), and its use in methods of treatment, including the treatment of bacterial infections. Methods for the preparation of the compound of formula (I) are also provided.
    Type: Application
    Filed: April 25, 2023
    Publication date: October 26, 2023
    Inventors: Pamela Brown, Michael Dawson, Mona Simonovic, Steven Boakes, Esther Duperchy, Steven James Stanway, Antoinette Wilson, Stephen Frederick Moss
  • POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS
    Publication number: 20230322858
    Abstract: Provided are compounds of formula (III), and the use of compounds of formula (III) in methods of treatment, such as methods of treating a microbial infection. The compounds of formula (III) is: where —R15 is an amino-containing group: and —R1, —R2, —R3, —R4, —R8, —RA, Q, —R16, —R17 are as described in further detail in the description.
    Type: Application
    Filed: March 24, 2023
    Publication date: October 12, 2023
    Inventors: Pamela BROWN, Michael DAWSON, Mona SIMONOVIC, Steven BOAKES, Esther DUPERCHY, Steven James STANWAY, Antoinette WILSON, Stephen Frederick MOSS
  • POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS
    Publication number: 20210221848
    Abstract: Provided are compounds of formula (III), and the use of compounds of formula (III) in methods of treatment, such as methods of treating a microbial infection. The compounds of formula (III) is: where —R15 is an amino-containing group: and —R1, —R2, —R3, —R4, —R, —RA, Q, —R16, —R17 are as described in further detail in the description.
    Type: Application
    Filed: January 25, 2021
    Publication date: July 22, 2021
    Inventors: Pamela BROWN, Michael DAWSON, Mona SIMONOVIC, Steven BOAKES, Esther DUPERCHY, Steven James STANWAY, Antoinette WILSON, Stephen Frederick MOSS
  • Compounds for use in antibacterial applications
    Patent number: 10683307
    Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: June 16, 2020
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Haifeng Cui, Alan Hennessy, Qi Jin, Timothy James Miles, Stephen Frederick Moss, Neil David Pearson
  • COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS
    Publication number: 20190270755
    Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.
    Type: Application
    Filed: May 17, 2019
    Publication date: September 5, 2019
    Inventors: Haifeng CUI, Alan Hennessy, Qi Jin, Timothy James Miles, Stephen Frederick Moss, Neil David Pearson
  • Compounds for use in antibacterial applications
    Patent number: 10364254
    Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: July 30, 2019
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Haifeng Cui, Alan Hennessy, Qi Jin, Timothy James Miles, Stephen Frederick Moss, Neil David Pearson
  • COMPOUNDS FOR US IN ANTIBACTERIAL APPLICATIONS
    Publication number: 20190031680
    Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.
    Type: Application
    Filed: August 15, 2016
    Publication date: January 31, 2019
    Inventors: Haifeng CUI, Alan HENNESSY, Qi JIN, Timothy James MILES, Stephen Frederick MOSS, Neil David PEARSON
  • COMPOUNDS
    Publication number: 20180030092
    Abstract: The present invention provides a compound of formula (I), and its use in methods of treatment, including the treatment of bacterial infections. Methods for the preparation of the compound of formula (I) are also provided.
    Type: Application
    Filed: November 26, 2015
    Publication date: February 1, 2018
    Inventors: Pamela Brown, Michael Dawson, Mona Simonovic, Steven Boakes, Esther Duperchy, Steven James Stanway, Antoinette Wilson, Stephen Frederick Moss
  • POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS
    Publication number: 20170073373
    Abstract: Provided are compounds of formula (III), and the use of compounds of formula (III) in methods of treatment, such as methods of treating a microbial infection. The compounds of formula (III) is: where —R15 is an amino-containing group: and —R1, —R2, —R3, —R4, —R8, —RA, Q, —R16, —R17 are as described in further detail in the description.
    Type: Application
    Filed: March 11, 2015
    Publication date: March 16, 2017
    Inventors: Pamela Brown, Michael Dawson, Mona Simonovic, Steven Boakes, Esther Duperchy, Steven James Stanway, Antoinette Wilson, Stephen Frederick Moss
  • Quinoline derivatives and their use as 5-HTligands
    Patent number: 8236947
    Abstract: Disclosed are quinoline compounds having affinity for the 5-HT6 receptor and having the formula: where R1, R2, R3, R4, R5, n, m, p and A are defined herein, and salts thereof, compositions containing these compounds and salts and processes for making and using the same.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: August 7, 2012
    Assignee: Glaxo Group Limited
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R Witty
  • QUINOLINE DERIVATIVES AND THEIR USE AS 5-HT6 LIGANDS
    Publication number: 20110237792
    Abstract: Disclosed are quinoline compounds having affinity for the 5-HT6 receptor and having the formula: where R1, R2, R3, R4, R5, n, m, p and A are defined herein, and salts thereof, compositions containing these compounds and salts and processes for making and using the same.
    Type: Application
    Filed: June 3, 2011
    Publication date: September 29, 2011
    Inventors: Mahmood AHMED, Christopher Norbert Johnson, Martin C. Johnes, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R. Witty
  • Quinoline derivatives and their use as 5-HT6 ligands
    Patent number: 7977337
    Abstract: Disclosed are quinoline compounds having affinity for the 5-HT6 receptor and having the formula: where R1, R2, R3, R4, R5, n, m, p and A are defined herein, and salts thereof, compositions containing these compounds and salts and processes for making and using the same.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: July 12, 2011
    Assignee: Glaxo Group Limited
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R Witty
  • QUINOLINE DERIVATIVES AND THEIR USE AS 5-HT6 LIGANDS
    Publication number: 20100305107
    Abstract: Disclosed are quinoline compounds having affinity for the 5-HT6 receptor and having the formula: where R1, R2, R3, R4, R5, n, m, p and A are defined herein, and salts thereof, compositions containing these compounds and salts and processes for making and using the same.
    Type: Application
    Filed: July 30, 2010
    Publication date: December 2, 2010
    Inventors: Mahmood AHMED, Christopher Norbert Johnson, Martin C. Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R. Witty
  • Quinoline derivatives and their use as 5-HTligands
    Patent number: 7799774
    Abstract: Disclosed are quinoline compounds having affinity for the 5-HT6 receptor and having the formula: where R1, R2, R3, R4, R5, n, m, p and A are defined herein, and salts thereof, compositions containing these compounds and salts and processes for making and using the same.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: September 21, 2010
    Assignee: Glaxo Group Limited
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R Witty
  • QUINOLINE DERIVATIVES AND THEIR USE AS 5-HT6 LIGANDS
    Publication number: 20090298841
    Abstract: The present invention relates to novel quinoline compounds having pharmacological activity, to processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders.
    Type: Application
    Filed: August 14, 2009
    Publication date: December 3, 2009
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C. Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R. Witty
  • Quinoline derivatives and their use as 5-HT6 ligands
    Patent number: 7601837
    Abstract: The present invention relates to novel quinoline compounds having pharmacological activity, to processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: October 13, 2009
    Assignee: Glaxo Group Limited
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, David R Witty
  • Heterocyclic urea derivatives for the treatment of pain
    Patent number: 7528151
    Abstract: Compounds of formula (I): or a pharmaceutically acceptable salt thereof, or a solvate thereof, wherein: P, P?, R1, R2, n, p, q, r, and s are as defined in the specification, processes for preparing such compounds, pharmaceutical compositions comprising such compounds and their use in therapy.
    Type: Grant
    Filed: March 5, 2004
    Date of Patent: May 5, 2009
    Assignee: Glaxo Group Limited
    Inventors: Stephen Frederick Moss, Harshad Kantilal Rami, Mervyn Thompson, David Richard Witty
  • Quinoline Derivatives and Their Use as 5-HT6 Ligands
    Publication number: 20090036682
    Abstract: The present invention relates to novel quinoline compounds having pharmacological activity, to processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders.
    Type: Application
    Filed: September 5, 2008
    Publication date: February 5, 2009
    Inventors: Mahmood AHMED, Christopher Norbert Johnson, Martin C. Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R. Witty
  • Quinoline Compounds Capable of Binding the Cb2 and/or the 5-Ht6 Receptor
    Publication number: 20090012056
    Abstract: The present invention relates to novel quinoline derivatives such as compounds of the formula (I) which possess antagonist potency for the 5-HT6 receptor and/or are capable of selectively modulating the cannabinoid 2 receptor: and the use of such compounds or pharmaceutical compositions thereof in the treatment of CNS disorders.
    Type: Application
    Filed: September 26, 2006
    Publication date: January 8, 2009
    Applicant: GLAXO GROUP LIMITED
    Inventors: Mahmood Ahmed, Gerard Martin Paul Giblin, Christopher Norbert Johnson, David George Hubert Livermore, Neil Derek Miller, Stephen Frederick Moss, David R. Witty
  • Quinoline derivatives and their use as 5-ht6 ligands
    Patent number: 7452888
    Abstract: Disclosed are novel quinoline compounds of formula (I), processes for their preparation, compositions containing them and their use in the treatment of CNS disorders.
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: November 18, 2008
    Assignee: Glaxo Group Limited
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C Jones, Gregor James Macdonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R Witty