Patents by Inventor Stephen Frederick Moss

Stephen Frederick Moss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 8-(1-Piperazinyl)-Quinoline Derivatives and Their Use in the Treatment of Cns Disorders
    Publication number: 20080275040
    Abstract: This invention relates to novel quinoline compounds having pharmacological activity, to processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders.
    Type: Application
    Filed: August 26, 2004
    Publication date: November 6, 2008
    Applicant: GLAXO GROUP LIMITED
    Inventors: Christopher Norbert Johnson, Stephen Frederick Moss, Malcolm M. Tait, David R. Witty
  • Piperazinyl-quinoline derivatives useful for the treatment of CNS disorders
    Patent number: 7439243
    Abstract: Disclosed are quinoline compounds of formula (I) having pharmacological activity, processes for their preparation, compositions containing them, and methods for the treatment of CNS and other disorders.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: October 21, 2008
    Assignee: Glaxo Group Limited
    Inventors: Christopher Norbert Johnson, Stephen Frederick Moss, David R Witty
  • 2-(pyrazol-3-yl)carbapenem derivatives
    Patent number: 7045619
    Abstract: A compound of formula (I): wherein R? is hydrogen, optionally substituted (C1-6)alkyl or optionally substituted aryl; R? is hydrogen, optionally substituted (C1-6)alkyl or optionally substituted aryl; or R? and R? together form an optionally substituted 5 or 6 membered heterocyclic ring with or without additional heteroatoms; R1 is (C1-6)alkyl which is unsubstituted or substituted by fluoro, a hydroxy group which is optionally protected by a removable hydroxy protecting group, or by an amino group which is optionally protected by a removable amino protecting group; R2 is hydrogen or methyl; and —CO2R3 is carboxy or a carboxylate anion or the group R3 is a removable carboxy protecting group. This invention also relates to processes for its preparation, intermediates and pharmaceutical compositions comprising compounds of formula (I).
    Type: Grant
    Filed: December 19, 2002
    Date of Patent: May 16, 2006
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Eric Hunt, Steven Coulton, Jeremy David Hinks, Stephen Frederick Moss, Stephen Christopher Martin Fell, Alfred John Eglington, George Burton
  • Isoquinoline derivatives useful in the treatment of CNS disorders
    Patent number: 6849644
    Abstract: The invention relates to novel tetrahydroquinoline compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of various CNS disorders.
    Type: Grant
    Filed: November 16, 2001
    Date of Patent: February 1, 2005
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Steven Mark Bromidge, Stephen Frederick Moss
  • Benzo[d]azepine derivatives as 5-ht6 receptor anatagonists
    Publication number: 20040192671
    Abstract: The invention relates to novel compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of various disorders.
    Type: Application
    Filed: May 19, 2004
    Publication date: September 30, 2004
    Inventors: Steven Mark Bromidge, Stephen Frederick Moss
  • Isoquinoline derivatives useful in the treatment of cns disorders
    Publication number: 20040053956
    Abstract: The invention relates to novel tetrahydroquinoline compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of various CNS disorders.
    Type: Application
    Filed: October 3, 2003
    Publication date: March 18, 2004
    Inventors: Steven Mark Bromidge, Stephen Frederick Moss
  • N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-piperazin-1-yl-benzenesulfonamide
    Publication number: 20040034036
    Abstract: The invention relates to a novel sulfonamide compound having pharmacological activity, a process for its preparation, to compositions containing the same and to its use in the treatment of various disorders, particularly CNS disorders.
    Type: Application
    Filed: June 9, 2003
    Publication date: February 19, 2004
    Inventors: Steven Mark Bromidge, Stephen Frederick Moss
  • 2-(pyrazol-3-yl)carbapenem derivatives
    Publication number: 20030166923
    Abstract: A compound of formula (I): 1
    Type: Application
    Filed: December 19, 2002
    Publication date: September 4, 2003
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Eric Hunt, Steven Coulton, Jeremy David Hinks, Stephen Frederick Moss, Stephen Christopher Martin Fell, Alfred John Eglington, George Burton
  • Compounds
    Patent number: 6548504
    Abstract: The present invention therefore provides, in a first aspect, a compound of formula (I) or a salt thereof: in which the group D is selected from a group of formula (A), (B) or (C) below: in which P is a monocyclic, bicyclic or tricyclic alicyclic ring containing up to 20 carbon atoms in the ring(s); A is a single bond, a C1-6alkylene or a C2-6alkenylene group; R1 is halogen, C1-6alkyl optionally substituted by one or more fluorine atoms, C3-6cycloalkyl, C1-6alkoxy, OCF3, hydroxy, hydroxyC1-6alkyl, hydroxyC1-6alkoxy, C1-6alkoxyC1-6alkoxy, C1-6alkanoyl, amino, alkylamino or dialkylamino, SR11 where R11 is hydrogen or C1-6alkyl or R1 is aryl, arylC1-6alkyl, a bicyclic heterocyclic ring or is a 5 to 7-membered heterocyclic ring each containing 1 to 4 heteroatoms selected from oxygen, nitrogen or sulfur; n is 0, 1, 2 or 3; and R2 is hydrogen, C1-6alkyl, aryl, arylC1-6alkyl or C3-6cycloalkyl; or in which Ra is an alkyl group containing 1 to 20 carbon atoms o
    Type: Grant
    Filed: July 19, 2000
    Date of Patent: April 15, 2003
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Steven Mark Bromidge, Stephen Frederick Moss
  • 2-(pyrazol-3-yl)carbapenem derivatives
    Publication number: 20020147333
    Abstract: A compound of formula (I): 1
    Type: Application
    Filed: January 23, 2002
    Publication date: October 10, 2002
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Eric Hunt, Steven Coulton, Jeremy David Hinks, Stephen Frederick Moss, Stephen Christopher Martin Fell, Alfred John Eglington, George Burton
  • Compounds
    Patent number: 6316450
    Abstract: The invention relates to novel compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of CNS disorders.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: November 13, 2001
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Steven Mark Bromidge, Stephen Frederick Moss