Patents by Inventor Stephen Gitu Machatha

Stephen Gitu Machatha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATIONS FOR TREATMENT OF DRY EYE DISEASE
    Publication number: 20200121591
    Abstract: The present invention provides a reproxalap ophthalmic solution, and methods of using the same for treating dry eye disease.
    Type: Application
    Filed: September 25, 2019
    Publication date: April 23, 2020
    Inventors: David Clark, Todd Brady, Susan Macdonald, Stephen Gitu Machatha
  • ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF
    Publication number: 20200062712
    Abstract: The present invention provides compounds and methods for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as MDA and HNE.
    Type: Application
    Filed: April 4, 2019
    Publication date: February 27, 2020
    Inventors: Stephen Gitu Machatha, Scott Young
  • TOPICAL COMPOSITIONS AND METHODS OF PREPARATION AND USE
    Publication number: 20200038392
    Abstract: The present invention provides topical, e.g., dermal, pharmaceutical compositions comprising an active agent. The present invention further provides methods of preparing such compositions and methods of treating a disease, disorder, or condition, such as a skin disease, using the same.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 6, 2020
    Inventors: Todd Brady, David Clark, Susan Macdonald, Stephen Gitu Machatha, Cameron Robert Stevenson, Charles Rodney Greenaway Evans
  • Treatment of allergic eye conditions with cyclodextrins
    Patent number: 10426790
    Abstract: The present disclosure provides methods of treating eye allergies and allergic conjunctivitis with cyclodextrin. Ophthalmic compositions of cyclodextrin for topical administration are also provided.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: October 1, 2019
    Assignee: Aldeyra Therapeutics, Inc.
    Inventors: Scott Young, Todd Brady, Stephen Gitu Machatha, David Clark, Susan Macdonald
  • ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF
    Publication number: 20180050989
    Abstract: The present invention provides compounds and methods for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as MDA and HNE.
    Type: Application
    Filed: August 22, 2017
    Publication date: February 22, 2018
    Inventors: Stephen Gitu Machatha, Scott Young
  • TREATMENT OF ALLERGIC EYE CONDITIONS WITH CYCLODEXTRINS
    Publication number: 20170266220
    Abstract: The present disclosure provides methods of treating eye allergies and allergic conjunctivitis with cyclodextrin. Ophthalmic compositions of cyclodextrin for topical administration are also provided.
    Type: Application
    Filed: February 28, 2017
    Publication date: September 21, 2017
    Inventors: Scott Young, Todd Brady, Stephen Gitu Machatha, David Clark, Susan Macdonald