Patents by Inventor Stephen L. Brown

Stephen L. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11952611
    Abstract: Disclosed herein are methods and systems for rapid detection of antibiotic resistance of a microorganism in a sample. A modified recombinant phage is also disclosed which comprises an indicator gene in the late gene region. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: April 9, 2024
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Minh Mindy Bao Nguyen, Dwight L. Anderson, Jose S. Gil, Stephen E. Erickson, Matthew J. Brown
  • Patent number: 11771717
    Abstract: The present invention relates to the treatment of cancer by irradiation by high energy photons, wherein the cancer has been infused with a heavy metal. The invention further relates to the use of pair-production for increased cancer cell destruction.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: October 3, 2023
    Assignee: Henry Ford Health System
    Inventors: Derek M. Isrow, Stephen L. Brown, Jae Ho Kim, Indrin J. Chetty, Panagiotis Tsiamas
  • Publication number: 20230189658
    Abstract: A top pinned SAF-containing magnetic tunnel junction structure is provided that contains a coupling spacer composed of a paramagnetic hexagonal metal phase material that has a stoichiometric ratio of Me3X or Me2X, wherein Me is a magnetic metal having a magnetic moment and X is a metal that alloys with Me in a hexagonal phase and dilutes the magnetic moment of Me. In embodiments in which a Me3X coupling spacer is present, Me is cobalt, and X is vanadium, niobium, tantalum, molybdenum or tungsten. In embodiments in which a Me2X coupling spacer is present, Me is iron and X is tantalum or tungsten. The coupling spacer is formed by providing a material stack including at least a precursor paramagnetic hexagonal metal phase material forming multilayered structure that includes alternating layers of magnetic metal, Me, and metal, X, and then thermally soaking the material stack.
    Type: Application
    Filed: December 14, 2021
    Publication date: June 15, 2023
    Inventors: Alexander Reznicek, MATTHIAS GEORG GOTTWALD, Stephen L Brown
  • Patent number: 11527707
    Abstract: A method for forming a memory device that includes providing a free layer of an alloy of cobalt (Co), iron (Fe) and boron (B) overlying a reference layer; and forming metal layer comprising a boron (B) sink composition atop the free layer. Boron (B) may be diffused from the free layer to the metal layer comprising the boron sink composition. At least a portion of the metal layer including the boron (B) sink composition is removed. A metal oxide is formed atop the free layer. The free layer may be a crystalline cobalt and iron alloy. An interface between the metal oxide and free layer can provide perpendicular magnetic anisotropy character.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: December 13, 2022
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stephen L. Brown, Guohan Hu, Jonathan Z. Sun, Daniel C. Worledge
  • Patent number: 11299801
    Abstract: A physical vapor deposition (PVD) target that includes a body composed of material that is reactive with an oxygen containing atmosphere; and a non-reactive cap layer encapsulating at least a sputter surface of the body. The non-reactive cap layer is a barrier obstructing the diffusion of oxygen containing species to the body of the PVD target.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: April 12, 2022
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stephen L. Brown, Bruce B. Doris, Mark C. Reuter
  • Publication number: 20220005999
    Abstract: Techniques facilitating formation of amorphous superconducting alloys for superconducting circuits are provided. A device can comprise one or more superconducting components that comprise an amorphous superconducting alloy comprising two or more elements. At least one element of the two or more elements is a superconducting element.
    Type: Application
    Filed: July 1, 2020
    Publication date: January 6, 2022
    Inventors: Christian Lavoie, Benjamin Wymore, Markus Brink, Stephen L. Brown
  • Patent number: 10639296
    Abstract: Mitigating radiation induced injury to a mammal that has been exposed to radiation by administering a pharmaceutically effective amount of a composition comprising at least one CXCR4 antagonist to the mammal.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: May 5, 2020
    Assignee: Henry Ford Health System
    Inventors: Jae Ho Kim, Stephen L. Brown, Andrew Kolozsvary
  • Publication number: 20200083438
    Abstract: A method for forming a memory device that includes providing a free layer of an alloy of cobalt (Co), iron (Fe) and boron (B) overlying a reference layer; and forming metal layer comprising a boron (B) sink composition atop the free layer. Boron (B) may be diffused from the free layer to the metal layer comprising the boron sink composition. At least a portion of the metal layer including the boron (B) sink composition is removed. A metal oxide is formed atop the free layer. The free layer may be a crystalline cobalt and iron alloy. An interface between the metal oxide and free layer can provide perpendicular magnetic anisotropy character.
    Type: Application
    Filed: November 18, 2019
    Publication date: March 12, 2020
    Inventors: Stephen L. Brown, Guohan Hu, Jonathan Z. Sun, Daniel C. Worledge
  • Publication number: 20200080191
    Abstract: A physical vapor deposition (PVD) target that includes a body composed of material that is reactive with an oxygen containing atmosphere; and a non-reactive cap layer encapsulating at least a sputter surface of the body. The non-reactive cap layer is a barrier obstructing the diffusion of oxygen containing species to the body of the PVD target.
    Type: Application
    Filed: November 13, 2019
    Publication date: March 12, 2020
    Inventors: Stephen L. Brown, Bruce B. Doris, Mark C. Reuter
  • Patent number: 10570504
    Abstract: A physical vapor deposition (PVD) target that includes a body composed of material that is reactive with an oxygen containing atmosphere; and a non-reactive cap layer encapsulating at least a sputter surface of the body. The non-reactive cap layer is a barrier obstructing the diffusion of oxygen containing species to the body of the PVD target.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: February 25, 2020
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stephen L. Brown, Bruce B. Doris, Mark C. Reuter
  • Patent number: 10553781
    Abstract: A method for forming a memory device that includes providing a free layer of an alloy of cobalt (Co), iron (Fe) and boron (B) overlying a reference layer; and forming metal layer comprising a boron (B) sink composition atop the free layer. Boron (B) may be diffused from the free layer to the metal layer comprising the boron sink composition. At least a portion of the metal layer including the boron (B) sink composition is removed. A metal oxide is formed atop the free layer. The free layer may be a crystalline cobalt and iron alloy. An interface between the metal oxide and free layer can provide perpendicular magnetic anisotropy character.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: February 4, 2020
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stephen L. Brown, Guohan Hu, Jonathan Z. Sun, Daniel C. Worledge
  • Publication number: 20200001111
    Abstract: The present invention relates to the treatment of cancer by irradiation by high energy photons, wherein the cancer has been infused with a heavy metal. The invention further relates to the use of pair-production for increased cancer cell destruction.
    Type: Application
    Filed: February 15, 2018
    Publication date: January 2, 2020
    Applicant: Henry Ford Health System
    Inventors: Derek M. ISROW, Stephen L. BROWN, Jae Ho KIM, Indrin J. CHETTY, Panagiotis TSIAMAS
  • Patent number: 10374145
    Abstract: A method for forming a memory device that includes providing a free layer of an alloy of cobalt (Co), iron (Fe) and boron (B) overlying a reference layer; and forming metal layer comprising a boron (B) sink composition atop the free layer. Boron (B) may be diffused from the free layer to the metal layer comprising the boron sink composition. At least a portion of the metal layer including the boron (B) sink composition is removed. A metal oxide is formed atop the free layer. The free layer may be a crystalline cobalt and iron alloy. An interface between the metal oxide and free layer can provide perpendicular magnetic anisotropy character.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: August 6, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stephen L. Brown, Guohan Hu, Jonathan Z. Sun, Daniel C. Worledge
  • Publication number: 20180312959
    Abstract: A physical vapor deposition (PVD) target that includes a body composed of material that is reactive with an oxygen containing atmosphere; and a non-reactive cap layer encapsulating at least a sputter surface of the body. The non-reactive cap layer is a barrier obstructing the diffusion of oxygen containing species to the body of the PVD target.
    Type: Application
    Filed: April 26, 2017
    Publication date: November 1, 2018
    Inventors: Stephen L. Brown, Bruce B. Doris, Mark C. Reuter
  • Publication number: 20180269044
    Abstract: A deposition tool includes a vacuum chamber and a physical vapor deposition module including a target source in the vacuum chamber. The target source includes a target material for depositing on a workpiece. An evaporator module is independent of the physical vapor deposition module and is mounted within an enclosure in the vacuum chamber. A gate is configured to selectively open the enclosure to permit evaporation of a coating element to coat the target source in the physical vapor deposition module.
    Type: Application
    Filed: March 20, 2017
    Publication date: September 20, 2018
    Inventors: Stephen L. Brown, Bruce B. Doris, Mark C. Reuter
  • Publication number: 20180269045
    Abstract: A deposition tool includes a vacuum chamber and a physical vapor deposition module including a target source in the vacuum chamber. The target source includes a target material for depositing on a workpiece. An evaporator module is independent of the physical vapor deposition module and is mounted within an enclosure in the vacuum chamber. A gate is configured to selectively open the enclosure to permit evaporation of a coating element to coat the target source in the physical vapor deposition module.
    Type: Application
    Filed: November 8, 2017
    Publication date: September 20, 2018
    Inventors: Stephen L. Brown, Bruce B. Doris, Mark C. Reuter
  • Publication number: 20180193307
    Abstract: Mitigating radiation induced injury to a mammal that has been exposed to radiation by administering a pharmaceutically effective amount of a composition comprising at least one CXCR4 antagonist to the mammal.
    Type: Application
    Filed: December 21, 2017
    Publication date: July 12, 2018
    Inventors: Jae Ho Kim, Stephen L. Brown, Andrew Kolozsvary
  • Publication number: 20170194556
    Abstract: A method for forming a memory device that includes providing a free layer of an alloy of cobalt (Co), iron (Fe) and boron (B) overlying a reference layer; and forming metal layer comprising a boron (B) sink composition atop the free layer. Boron (B) may be diffused from the free layer to the metal layer comprising the boron sink composition. At least a portion of the metal layer including the boron (B) sink composition is removed. A metal oxide is formed atop the free layer. The free layer may be a crystalline cobalt and iron alloy. An interface between the metal oxide and free layer can provide perpendicular magnetic anisotropy character.
    Type: Application
    Filed: March 23, 2017
    Publication date: July 6, 2017
    Inventors: Stephen L. Brown, Guohan Hu, Jonathan Z. Sun, Daniel C. Worledge
  • Publication number: 20170110506
    Abstract: A method for forming a memory device that includes providing a free layer of an alloy of cobalt (Co), iron (Fe) and boron (B) overlying a reference layer; and forming metal layer comprising a boron (B) sink composition atop the free layer. Boron (B) may be diffused from the free layer to the metal layer comprising the boron sink composition. At least a portion of the metal layer including the boron (B) sink composition is removed. A metal oxide is formed atop the free layer. The free layer may be a crystalline cobalt and iron alloy. An interface between the metal oxide and free layer can provide perpendicular magnetic anisotropy character.
    Type: Application
    Filed: October 14, 2015
    Publication date: April 20, 2017
    Inventors: Stephen L. Brown, Guohan Hu, Jonathan Z. Sun, Daniel C. Worledge
  • Publication number: 20160303074
    Abstract: Mitigating radiation induced injury to a mammal that has been exposed to radiation by administering a pharmaceutically effective amount of a composition comprising at least one CXCR4 antagonist to the mammal at least once within a decisive treatment window wherein the window opens 48 hours after exposure.
    Type: Application
    Filed: June 20, 2016
    Publication date: October 20, 2016
    Inventors: Jae Ho Kim, Stephen L. Brown, Andrew Kolozsvary