Publication number: 20100113326
Abstract: Compounds made up of a homodimer or heterodimer having monomeric units of formula (I): wherein: each A is, independently, NR1R2, or N+R1R2R3; each B is, independently, optionally substituted alkyl, alkenyl, or alkynyl, wherein one or more hydrogens are optionally replaced by fluorine; each U is, independently, CONH, C(O)O, C(S)O, C(S)NH, C(NH)NH, (CH2)1-5, or the inverse, thereof, wherein one or more carbons are optionally replaced by a heteroatom selected from O, S, and N; each V and W is, independently, (CH2)1-5, wherein one or more carbons are optionally replaced by C?O, C?S, or a heteroatom selected from O, S, and N, and one or more hydrogens are optionally replaced by a branched or unbranched alkyl or cycloalkyl, an optionally substituted aryl, arylalkyl, heteroaryl, heteroarylalkyl, OR4, SR4, or NR4R5; each X is, independently, optionally substituted alkyl, alkenyl, alkynyl, aryl, or heteroaryl, wherein one or more carbons are optionally replaced by C?O, C?S, or a heteroatom selected from O, S, and N, a
Type:
Application
Filed:
July 24, 2007
Publication date:
May 6, 2010
Applicant:
TETRALOGIC PHARMACEUTICALS CORPORATION
Inventor:
Stephen M. Condon