Abstract: The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and a rotatably displaceable member for individually opening and closing any of said shafts to enable the flow of fluid therethrough. Flexible conduits (e.g., flexible tubing) are equal in number to the shafts, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.

Abstract: The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and a rotatably displaceable member for individually opening and closing any of said shafts to enable the flow of fluid therethrough. Flexible conduits (e.g., flexible tubing) are equal in number to the shafts, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.

Abstract: A connector is provided for connecting a flexible conduit with a second conduit having a barbed outer surface. The connector accommodates the end of the flexible conduit and the end of the second conduit in a manner which prevents removal of the flexible conduit and the second conduit from the connector. Optionally, the connector has a ring that may be used to apply additional pressure and security to the outer surface of the flexible conduit. additionally, the connector may have a wireless enabled communication and optionally, memory device such as a RFID tag attached or affixed to it.

Abstract: The invention provides a disposable cell culture bioreactor manifold system for use in coupling sensors, fluid samplers, conduits, and the like, to a cell culture bioreactor in a sterile manner. The disposable bioreactor manifold system includes an externally attachable bioreactor manifold connector body for fluidly attaching modular sensor arrangements that measure physical variables and other parameters of medium contained within a bioreactor, as well as medium sampling components, and other connections, as well as at least one conduit fluidly connecting connecting the bioreactor manifold connector body with a pump for pumping fluids between the bioreactor and the bioreactor manifold connector body.

Abstract: The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and a rotatably displaceable member for individually opening and closing any of said shafts to enable the flow of fluid therethrough. Flexible conduits (e.g., flexible tubing) are equal in number to the shafts, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.

Abstract: A method for over-molding a tubular filter element 16, at least at one end 16b thereof, with a thermoplastic end cap 12. The over-molding method can be used to manufacture easily and cost-effectively a filter cartridge, of good durability, from an unprecedented range of polymeric materials and components. The thermoplastic over-molding method does not require pre-lamination of said end 16b, and can be performed at temperatures and pressures that do not result in undesirable morphological changes in the tubular filtration medium. Exemplary filter cartridges made through the over-molding method comprise a tubular filtration medium interposed between thermoplastic end caps, the thermoplastic material of the end caps infiltrating the tubular filtration medium, thereby creating mechanical interlock zones at the ends thereof.

Abstract: The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and a rotatably displaceable member for individually opening and closing any of said shafts to enable the flow of fluid therethrough. Flexible conduits (e.g., flexible tubing) are equal in number to the shafts, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.

Abstract: A method for over-molding a tubular filter element 16, at least at one end 16b thereof, with a thermoplastic end cap 12. The over-molding method can be used to manufacture easily and cost-effectively a filter cartridge, of good durability, from an unprecedented range of polymeric materials and components. The thermoplastic over-molding method does not require pre-lamination of said end 16b, and can be performed at temperatures and pressures that do not result in undesirable morphological changes in the tubular filtration medium. Exemplary filter cartridges made through the over-molding method comprise a tubular filtration medium interposed between thermoplastic end caps, the thermoplastic material of the end caps infiltrating the tubular filtration medium, thereby creating mechanical interlock zones at the ends thereof.

Abstract: A connector is provided for connecting a flexible conduit with a second conduit having a barbed outer surface. The connector accommodates the end of the flexible conduit and the end of the second conduit in a manner which prevents removal of the flexible conduit and the second conduit from the connector. Optionally, the connector has a ring that may be used to apply additional pressure and security to the outer surface of the flexible conduit. additionally, the connector may have a wireless enabled communication and optionally, memory device such as a RFID tag attached or affixed to it.

Abstract: The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and a rotatably displaceable member for individually opening and closing any of said shafts to enable the flow of fluid therethrough. Flexible conduits (e.g., flexible tubing) are equal in number to the shafts, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.

Abstract: A connector is provided for connecting a flexible conduit with a second conduit having a barbed outer surface. The connector accommodates the end of the flexible conduit and the end of the second conduit in a manner which prevents removal of the flexible conduit and the second conduit from the connector. Optionally, the connector has a ring that may be used to apply additional pressure and security to the outer surface of the flexible conduit. additionally, the connector may have a wireless enabled communication and optionally, memory device such as a RFID tag attached or affixed to it.

Abstract: A filtration apparatus is provided wherein a filtration membrane is positioned by gaskets on feed plates and filtrate plates rather than being bonded thereto.

Abstract: The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and a rotatably displaceable member for individually opening and closing any of said shafts to enable the flow of fluid therethrough. Flexible conduits (e.g., flexible tubing) are equal in number to the shafts, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.

Abstract: The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and sample gating means for individually opening and closing any of said shafts to enable the flow of fluid therethrough. The flexible conduits (e.g., flexible tubing) are equal in number to the elongate member, with each flexible conduit connected to or otherwise in fluid communication with an individual shaft. Similarly, the sample containers (e.g., flexible bags) are equal in number to the conduits, with each sample container connected to an individual conduit opposite the connection to the shaft. A specific configuration for the port insert, as well as kit containing sterilized components of the fluid sampling device, are also described.

Abstract: A single-use fluid dispenser cartridge, installable or installed into a host fluid dispensing apparatus, is described. The single-use fluid dispenser cartridge is provided with a fluid reservoir, a fill tube assembly, and means for controlling pressure within the cartridge by gating gas into or out of the reservoir and/or the fill tube assembly. The gas gating mean enables, in certain embodiments, use of a fluid reservoir that is “substantially rigid”.

Abstract: A disposable tube set apparatus is provided for delivering a precise volume of a fluid to containers which comprise a reservoir for a fluid, an inlet conduit to the said reservoir, at least one first outlet conduits from the reservoir, a sight tube connected to each of the at least one outlet conduit, each of the sight outlet tubes having an interior wall tapered away from a central vertical axis of each of the sight outlet tubes, a return conduit connecting each of the sight outlet tubes to the reservoir, and a second outlet conduit connected to each of the sight tubes.

Abstract: The present invention relates to a stand for holding disposable filter capsules and is formed of three or more legs, a base above the legs and to which the leg as are attached and three or more arms that are attached to an opposite surface of the base from that of the legs. The arms and legs have at least curved or angled portion that allows for the arms and legs to spread out from the diameter of the base. Preferably, the arms have a second curved or angled portion that then allows the upper portion of the arms to become substantially vertical.

Abstract: A disposable tube set apparatus is provided apparatus for delivering a precise volume of a fluid to containers which comprise a reservoir for a fluid, an inlet conduit to said reservoir, at least one first outlet conduits from said reservoir, a sight tube connected to each of said at least one outlet conduit, each of said sight outlet tubes having an interior wall tapered away from a central vertical axis of each of said sight outlet tubes, a return conduit connecting each of said sight outlet tubes to said reservoir, and a second outlet conduit connected to each of said sight tubes.

Abstract: The present invention relates to a stand for holding disposable filter capsules and is formed of three or more legs, a base above the legs and to which the leg as are attached and three or more arms that are attached to an opposite surface of the base from that of the legs. The arms and legs have at least curved or angled portion that allows for the arms and legs to spread out from the diameter of the base. Preferably, the arms have a second curved or angled portion that then allows the upper portion of the arms to become substantially vertical.