Abstract: Embodiments enable communicable integration of a user network of devices and an internet of things (TOT) device. Embodiments identify an TOT device location; calculate a first limit based on a difference between the location of the user and the TOT device location; continuously identify a real-time location of the user via the one or more components of the user network of devices; calculate a total time to user arrival at the TOT device location; calculate a second time limit based on preparation of the TOT device; if the total time to user arrival at the TOT device location is greater than the second time limit, continuously monitor the total time to user arrival at the TOT device location; and when the total time to user arrival at the TOT device location is less than or equal to the second time limit, activate the TOT device for preparation.

Abstract: Embodiments of the present invention provide a communicable integration of a user network of devices and a vendor system. Embodiments receive, at the vendor system from the user network of devices, a request for provisioning of products by a vendor; determine a provisioning location for provisioning of the products by the vendor; continuously identify a real-time location of the user via the one or more components of the user network of devices; continuously calculate a real-time first limit based on the continuously identified current location of the user and the provisioning location; calculate a total time to provision the products comprising a sum of a product preparation time and the real-time first limit; and optimize delivery of the products based on the total time to provision and the real-time location of the user.

Abstract: Embodiments of the present invention provide a system for transferring one or more resources associated with an interaction via an automobile. The system is typically configured for receiving an input from a user to search for a parking space, communicating with one or more remote parking systems at one or more parking locations within a predetermined distance from a destination to identify one or more available parking spaces, applying logic to select a first parking space from the one or more available parking spaces, transmit a location of the first parking space to the user, continuously monitoring a real-time location of the user, identifying that the real-time location of the user matches the location of the first parking space, initiating transfer of resources to complete an interaction with a first remote parking system associated with the first parking space, and completing the interaction by transferring the resources to the first remote parking system.

Abstract: Embodiments of the present invention provide a system for transferring one or more resources associated with an interaction via an automobile. The system is typically configured for receiving a travel route to a destination from a user, via one or more components of an automobile, identifying one or more tolls associated with the travel route, continuously monitoring a current location of the user, identifying that the current location of the user is within a predetermined distance from a toll location of the one or more tolls, establishing a communication link with at least one remote toll system associated with the toll location based on identifying that the current location is within the predetermined distance from the toll location, initiating transfer of resources to complete an interaction with the at least one remote toll system, and completing the interaction by transferring the resources to the at least one remote toll system.

Abstract: Embodiments of the present invention provide a system for transferring one or more resources associated with an interaction via an automobile. The system is typically configured for receiving an input from a user, via one or components of an automobile, to identify one or more third party entities associated with an interaction, identifying, via the one or more components, a current location and a destination of the user, identifying the one or more third party entities between the current location and the destination, applying logic to select a third party entity from the one or more third party entities, establishing a communication link with a third party entity device associated with the third party entity, and initiating transfer of resources to the remote device to complete the interaction.

Abstract: Techniques for onboarding users to various product features are described. According to various embodiments, information identifying a set of candidate onboarding content items associated with an email type of an email to be transmitted to a particular member of an online social network service is accessed. Thereafter, a first subset of the candidate onboarding content items is removed from the set, responsive to determining that the particular member has already been onboarded to products associated with the candidate onboarding content items in the first subset. Further, a second subset of the candidate onboarding content items is removed from the set, responsive to determining that the particular member has previously viewed and not interacted with the candidate onboarding content items in the second subset. A specific onboarding content item is then dynamically selected from the remaining set of candidate onboarding content items.

Abstract: The present invention is directed to 4?-substituted nucleoside derivatives of Formula (I) and their use in the inhibition of HIV reverse transcriptase, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS and/or ARC. The present invention also provides processes for the preparation of 4?-substituted nucleoside derivatives of Formula (I) and derivatives thereof.

Abstract: Metal complexes such as those of formula (I) are contemplated by the present invention. The metal complexes may be used in catalytic reactions as a catalyst. The catalytic reaction may be an autotransfer process, for example hydrogen borrowing.

Abstract: A system for testing an impact of a vehicle includes a rail, a cable moveable along the rail, a shuttle fixed to the cable and slideably coupled to the rail, and a cart. The cart includes a connector horizontally spaced from the rail and a centerline parallel to and horizontally spaced from the rail. An arm is fixed to the shuttle and extends from the shuttle to the connector. The arm is releasably connectable to the connector.

Abstract: The present invention provides an electrolysis system for producing an electrolyzed water composition. The system comprises a reservoir (2) comprising an aqueous electrolyte solution. The system further comprises an electrolytic flow cell (4) in fluid communication with the reservoir (2) to receive a feed stream comprising aqueous electrolyte solution. The cell (4) comprises a plurality of boron doped diamond electrodes, in which the electrodes are connected to a power supply operable to provide an over-potential to the electrolyte solution to produce an electrolyzed water feed stream comprising a plurality of active molecular and ionic species. The system further comprises a control system (8) operable to control the power supply unit (11) in dependence on the salt concentration of the electrolyte solution to provide a predetermined voltage to the cell.

Abstract: A test apparatus includes a linear motion generator, an airbag, a plate, a platform, an anthropomorphic test device, and a crushable member. The airbag is spaced from the linear motion generator. The plate is moveable by the linear motion generator toward the airbag, and the platform is fixed relative to the plate. The anthropomorphic test device is adjacent the airbag and includes an end coupled to the platform. The crushable member is disposed between the plate and the platform, and the crushable member is deformable by the plate. During operation of the test apparatus, the linear motion generator moves the plate into the crushable member to slow movement of the anthropomorphic device toward the airbag. The crushable member crushes to simulate the forces on the anthropomorphic test device from a vehicle side impact.

Abstract: The present invention provides an aqueous electrolyte solution comprising at least four salts. The at least four salts are selected from: at least one salt selected from alkali metal chloride, alkali earth metal chloride, and ammonium chloride, or any combination thereof; at least one salt selected from alkali metal carbonate; alkali earth metal carbonate, and ammonium carbonate, or any combination thereof; at least one salt selected from alkali metal nitrate, alkali earth metal nitrate, and ammonium nitrate, or any combination thereof; and at least one salt selected from alkali metal phosphate, alkali earth metal phosphate, and ammonium phosphate, or any combination thereof.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: An assembly to simulate side impacts to a vehicle includes a rocker, a translatable sled, and one or more displacement members. The rocker is secured to a wall. A b-pillar extends from the rocker and a roof rail is secured to the b-pillar and the wall. The translatable sled is arranged with the wall to impact the b-pillar. The one or more displacement members are secured to the wall and spaced from the rocker to simulate a stiffness of a full vehicle frame during impact between the sled and the b-pillar. A first rocker end constraint may secure a first end of the rocker to the wall. A second rocker end constraint may secure a second end of the rocker to the wall. The constraints may be arranged with the rocker such that the ends of the rocker may pivot relative to the wall.

Abstract: A composition comprising an enzyme, a mycotoxin-binding agent and a microorganism capable of taking up a mycotoxin.

Abstract: An auto-injector automatically dispenses a predetermined dose of medicament upon activation. The auto-injector includes a needle cover operative to engage an injection site and activate the injector. The needle cover is configured to move from a locked retracted position prior to a medicament dispensing operation to a locked extended position after the medicament dispensing operation. The non-removable needle cover prevents contact with the needle both before and after the medicament dispensing operation.

Abstract: The cabinet 1 has a base 3 that defines an opening 7, which is sized to receive the tynes of a lifting device, such as a fork lift of the like, for example. This facilitates transportation of the entire cabinet 1. The cabinet 1 has nine drawers 8, each having formations, in the form of a pair of slots 10 and 11, which are adapted for engagement with the tynes. Once the tynes have been inserted, the lifting device operator may then raise the tynes slightly, thereby supporting the drawer 8 on the tynes. The lifting device operator can then remove the drawer 8 that is being supported by the tynes from the cabinet 1.

Abstract: An assembly to simulate side impacts to a vehicle includes a rocker, a translatable sled, and one or more displacement members. The rocker is secured to a wall. A b-pillar extends from the rocker and a roof rail is secured to the b-pillar and the wall. The translatable sled is arranged with the wall to impact the b-pillar. The one or more displacement members are secured to the wall and spaced from the rocker to simulate a stiffness of a full vehicle frame during impact between the sled and the b-pillar. A first rocker end constraint may secure a first end of the rocker to the wall. A second rocker end constraint may secure a second end of the rocker to the wall. The constraints may be arranged with the rocker such that the ends of the rocker may pivot relative to the wall.

Abstract: The invention relates to compounds in the treatment or prevention of disorders associated with Lamin A and/or Lamin C depletion or LMNA mutations, such as laminopathy, premature ageing disorders, normal ageing and cancer (such as a cancer characterized by low levels of LMNA expression).

Abstract: The present invention provides a method for producing electrolyzed water composition for use in cleaning and disinfecting of an object. The method comprises preparing an electrolyte solution comprising water, at least one carbonate salt selected from: alkali metal carbonate salts, and at least one chloride salt selected from: alkali metal chloride salts and/or alkali earth metal chloride salts. The method further comprises introducing the aqueous electrolyte solution into an electrolytic cell comprising a plurality of boron-doped diamond electrodes. The method further comprises operating a power supply to apply a predetermined voltage to the electrolyte solution to produce an electrolyzed water composition comprising a plurality of active molecular and ionic species with antimicrobial activity.