Abstract: A vascular occlusion device deployment system is provided for deploying an embolic device at a preselected site within the vasculature of a patient. The deployment system includes a tubular element having a catch movably located within the tubular element. The catch has a normal open configuration and a closed configuration. When in the closed configuration, the catch grasps a headpiece of an embolic device. The tubular element has a constraining section and a releasing section. When the catch is within the constraining section of the tubular element, the constraining section acts upon the catch to keep the catch in a closed configuration. When the catch is moved to the releasing section, the catch returns to its normally open configuration and releases its grasp of the embolic device headpiece.

Abstract: A recruiting system and method includes an automated candidate opt-in confirmation system for identifying and screening job candidate resumes that permits at least one potential candidate to opt-in to seek a job opportunity. The recruiting system enables a candidate to opt-in using a telephone, the Internet, or through any other suitable mediums or methods. The recruiting system and method provides a highly effective tool for job recruiters to select and identify qualified candidates that want to pursue a specified job opportunity quickly and efficiently.

Abstract: The present invention is concerned with improvements to methods of imaging nucleotides incorporated into polynucleotides and in particular with improved methods of determining the sequence of template nucleic acid molecules using multiple cycle nucleic acid “sequencing-by-synthesis” reactions.

Abstract: The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template.

Abstract: The present invention is directed to a method for reducing the complexity of a nucleic acid sample in a reproducible manner by enriching for specific nucleic acid target sequences in the population of nucleic acids. More specifically, the invention relates to a method for enriching specific target sequences in a population using libraries of oligonucleotides.

Abstract: A method for controlling access to triple play services provided through a server over a network to a target system, the method comprising: receiving a signal from a user to select a service from a list of the services displayed on a display screen of a data processing system; receiving a signal from the user to select a control for configuring access to the service from a list of controls displayed on the display screen, each control representing a respective strategy for controlling access to the service; receiving a signal from the user providing respective parameter values for parameters in a list of parameters displayed on the display screen for the control, the parameters for controlling access to the service for the target system; and, sending the parameter values to the server, wherein the server controls access to the service for the target system in accordance with the parameter values.

Abstract: A vascular occlusion device deployment system is provided for deploying an embolic device at a preselected site within the vasculature of a patient. The deployment system includes a tubular element having a catch movably located within the tubular element. The catch has a normal open configuration and a closed configuration. When in the closed configuration, the catch grasps a headpiece of an embolic device. The tubular element has a constraining section and a releasing section. When the catch is within the constraining section of the tubular element, the constraining section acts upon the catch to keep the catch in a closed configuration. When the catch is moved to the releasing section, the catch returns to its normally open configuration and releases its grasp of the embolic device headpiece.

Abstract: A balloon catheter for medical treatment of a patient, including therapeutic dilatation or deployment of medical devices such as stents or grafts. The balloon catheter has an “over-the-wire configuration, including a proximal hub defining an inflation port and a guidewire port, a flexible shaft defining an inflation lumen and a guidewire lumen, a balloon near a distal end of the catheter, and a distal guidewire port. At least a portion of the shaft has an inner tubular body defining at least a portion of the guidewire lumen, surrounded by an outer tubular body defining at least a portion of the inflation lumen. A proximal portion of the inner body is reinforced by a hypotube, which provides much greater column strength and torsional stiffness. A distal end of the hypotube provides a graduated flexibility transition with a distal spiral-cut segment, in which the pitch of the spiral cut pattern decreases to provide increasing flexibility.

Abstract: An aneurysm embolization device and deployment system for use in occluding the flow of blood at a preselected position within a vessel of the human body comprising a headpiece and a plurality of spherical members linked together with a central connecting member, which, when deployed the embolization device occludes the flow of blood in a high volume or wide neck aneurysm.

Abstract: An aneurismal sack deflator is disclosed including a body having an aneurismal sack neck closure surface. An internal surface defines at least a portion of a fluid passageway, with the internal surface configured to provide a Venturi effect to thereby reduce fluid pressure in the fluid passageway. A semi-permeable region is in fluid communication with the fluid passageway and the aneurismal sack. The semi-permeable region permits first blood components to pass therethrough out of the aneurismal sack and into the fluid passageway when the lower surface is under reduced pressure and does not permit second blood components to pass therethrough.

Abstract: An aneurysm embolization device and deployment system for use in occluding the flow of blood at a preselected position within a vessel of the human body comprising a headpiece and a plurality of spherical members linked together with a central connecting member, which, when deployed the embolization device occludes the flow of blood in a high volume or wide neck aneurysm.

Abstract: A clot retrieval device includes a clot retrieval unit having a pusher member and a retrieval basket connected to the distal end of the pusher member. The retrieval basket is transformable between an expanded state and a contracted state. The retrieval basket also includes a closeable opening in the distal end for receiving a clot into the retrieval basket. The opening and the transition between the expanded and contracted states are controlled by a control wire connected to the distal end of the retrieval basket.

Abstract: A balloon catheter for medical treatment of a patient, including therapeutic dilatation or deployment of medical devices such as stents or grafts. The balloon catheter has an “over-the-wire configuration, including a proximal hub defining an inflation port and a guidewire port, a flexible shaft defining an inflation lumen and a guidewire lumen, a balloon near a distal end of the catheter, and a distal guidewire port. At least a portion of the shaft has an inner tubular body defining at least a portion of the guidewire lumen, surrounded by an outer tubular body defining at least a portion of the inflation lumen. A proximal portion of the inner body is reinforced by a hypotube, which provides much greater column strength and torsional stiffness. A distal end of the hypotube provides a graduated flexibility transition with a distal spiral-cut segment, in which the pitch of the spiral cut pattern decreases to provide increasing flexibility.

Abstract: An aneurysm embolization device and deployment system for use in occluding the flow of blood at a preselected position within a vessel of the human body comprising a headpiece and a plurality of spherical members linked together with a central connecting member, which, when deployed the embolization device occludes the flow of blood in a high volume or wide neck aneurysm.

Abstract: A fuel system includes a pair of electronically controllable high pressure fuel pumps operable to supply high pressure fuel from a lower pressure fuel source to a high pressure fuel collection chamber having a pressure sensor associated therewith. The fuel collection chamber feeds an electronically controllable valve operable to dispense the high pressure fuel to a fuel distribution unit supplying fuel to a number of fuel injectors. A control computer is provided for controlling the high pressure fuel pump and valve in response to requested fueling, engine speed and fuel pressure provided by the pressure sensor. The accumulator pressure profile is processed in accordance with various techniques forming part of the present invention for diagnosing pressure sensor in-range failures, fuel pump injector valve blow shut failures and failure of one of the fuel pumps.

Abstract: A system is disclosed for determining an effective throttle value of an internal combustion engine for controlling automatic transmission shift points. In one embodiment, the system is operable to determine an effective throttle value as a function of commanded fueling and engine speed under operating conditions wherein engine torque is requested by a system/component other than manual throttle control to thereby provide a throttle value indicative of what throttle position or percentage would be under present operating conditions if engine torque was being requested via manual throttle control. The present invention accordingly overcomes deficiencies in known automatic transmission shift point control systems by continuously computing an equivalent throttle percentage whenever fueling or requested torque values are not dominated by actual throttle (e.g. accelerator pedal) percentage.

Abstract: A fuel system includes a pair of electronically controllable high pressure fuel pumps operable to supply high pressure fuel from a lower pressure fuel source to a high pressure fuel accumulator having a pressure sensor associated therewith. The fuel collection chamber feeds an electronically controllable valve operable to dispense the high pressure fuel to a fuel distribution unit supplying fuel to a number of fuel injectors. A control computer is provided for controlling the high pressure fuel pump and valve in response to requested fueling, engine speed and fuel pressure provided by the pressure sensor. The accumulator pressure signal is processed in accordance with the present invention for diagnosing erratic pressure sensor failures. The control computer is operable to compute error pressure values based on differences between peak accumulator pressure values and a target pressure value, and compute pressure error variance values based on subsets of the pressure error values.

Abstract: A fuel system includes a pair of electronically controllable high pressure fuel pumps operable to supply high pressure fuel from a lower pressure fuel source to a high pressure fuel collection chamber having a pressure sensor associated therewith. The fuel collection chamber feeds an electronically controllable valve operable to dispense the high pressure fuel to a fuel distribution unit supplying fuel to a number of fuel injectors. A control computer is provided for controlling the high pressure fuel pump and valve in response to requested fueling, engine speed and fuel pressure provided by the pressure sensor. The accumulator pressure profile is processed in accordance with various techniques forming part of the present invention for diagnosing pressure sensor in-range failures, fuel pump injector valve blow shut failures and failure of one of the fuel pumps.

Abstract: A fuel system includes a pair of electronically controllable high pressure fuel pumps operable to supply high pressure fuel from a lower pressure fuel source to a high pressure fuel accumulator having a pressure sensor associated therewith. The fuel collection chamber feeds an electronically controllable valve operable to dispense the high pressure fuel to a fuel distribution unit supplying fuel to a number of fuel injectors. A control computer is provided for controlling the high pressure fuel pump and valve in response to requested fueling, engine speed and fuel pressure provided by the pressure sensor. The accumulator pressure signal is processed in accordance with the present invention for diagnosing erratic pressure sensor failures. The control computer is operable to compute error pressure values based on differences between peak accumulator pressure values and a target pressure value, and compute pressure error variance values based on subsets of the pressure error values.

Abstract: A fuel system includes an electronically controllable high pressure fuel pump operable to supply high pressure fuel from a lower pressure fuel source to a high pressure fuel collection chamber having a pressure sensor associated therewith. The fuel collection chamber feeds an electronically controllable valve operable to dispense the high pressure fuel to a fuel distribution unit supplying fuel to a number of fuel injectors. A control computer is provided for controlling the high pressure fuel pump and valve in response to requested fueling, engine speed and fuel pressure provided by the pressure sensor. The control computer is normally operable to drive the fuel pump as a function of fuel pressure and a reference pressure, which is based on requested fueling, and to control the valve as a function of commanded fueling, which is a function of engine speed and a reference speed based on requested fueling, and fuel pressure.