Patents by Inventor Stephen Zhou

Stephen Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Emergency lighting system with differential dimming
    Publication number: 20210153311
    Abstract: An emergency lighting system uses a wireless mesh network to control the dimming of luminaires in the event of a power failure or a power outage. Luminaires are commissioned to different dimming power levels depending on localized lighting needs during the power failure of power outage.
    Type: Application
    Filed: November 18, 2020
    Publication date: May 20, 2021
    Applicant: McWong Inc.
    Inventors: Blane Goettle, Stephen Zhou, Michael Darren Musgrove, Stan Ouyang
  • Device and method of forming decorative panel
    Patent number: 10279547
    Abstract: The present invention in one or more embodiments provides a method of forming an opening on a panel, the method including pressing in a first direction on the panel to form a protrusion with a tip portion, and cutting the protrusion with a force in a second direction to remove the tip portion to form the opening on the panel, the second direction being different from the first direction. The first direction may be a direction of gravity plus and minus up to 15 degrees. The second direction may be transverse to the first direction with an angle differential there-between of 75 to 105 degrees.
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: May 7, 2019
    Assignee: Ford Global Technologies, LLC
    Inventors: Tom Xu, Gary D. Mullen, Peter Zhang, Stephen Zhou, Frank Hu
  • ANTAGONIST ANTI-NOTCH3 ANTIBODIES AND THEIR USE IN THE PREVENTION AND TREATMENT OF NOTCH3-RELATED DISEASES
    Publication number: 20180291090
    Abstract: The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
    Type: Application
    Filed: December 15, 2017
    Publication date: October 11, 2018
    Applicant: GENENTECH, INC.
    Inventors: Sek Chung Fung, Kang Li, Yucheng Li, Sanjaya Singh, Bin-Bing Stephen Zhou
  • ANTI-NOTCH3 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES
    Publication number: 20170014526
    Abstract: The present invention provides for anti-Notch3 antibodies, anti-Notch3 antibody-drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: July 27, 2016
    Publication date: January 19, 2017
    Applicant: Pfizer Inc.
    Inventors: Kenneth G. Geles, Yijie Gao, Puja Sapra, Lioudmila Gennadievna Tchistiakova, Bin-Bing Stephen Zhou
  • Anti-Notch3 agonist antibodies and their use in the treatment of Notch3-related diseases
    Patent number: 9518124
    Abstract: The present invention relates to agonist antibodies that specifically bind to Notch 3 and activate signaling. The present invention includes antibodies binding to an epitope comprising the first Lin12 domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: December 13, 2016
    Assignee: Genentech, Inc.
    Inventors: Kang Li, Bin-Bing Stephen Zhou, Wenjuan Wu, Sek Chung Fung, Sanjaya Singh
  • Anti-Notch3 antibodies and antibody-drug conjugates
    Patent number: 9433687
    Abstract: The present invention provides for anti-Notch3 antibodies, anti-Notch3 antibody-drug conjugates and methods for preparing and using the same.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: September 6, 2016
    Assignee: Pfizer Inc.
    Inventors: Kenneth G. Geles, Yijie Gao, Puja Sapra, Lioudmila Gennadievna Tchistiakova, Bin-Bing Stephen Zhou
  • DEVICE AND METHOD OF FORMING DECORATIVE PANEL
    Publication number: 20160052213
    Abstract: The present invention in one or more embodiments provides a method of forming an opening on a panel, the method including pressing in a first direction on the panel to form a protrusion with a tip portion, and cutting the protrusion with a force in a second direction to remove the tip portion to form the opening on the panel, the second direction being different from the first direction. The first direction may be a direction of gravity plus and minus up to 15 degrees. The second direction may be transverse to the first direction with an angle differential there-between of 75 to 105 degrees.
    Type: Application
    Filed: July 23, 2015
    Publication date: February 25, 2016
    Inventors: TOM XU, GARY D. MULLEN, PETER ZHANG, STEPHEN ZHOU, FRANK HU
  • ANTI-NOTCH1 ANTIBODIES
    Publication number: 20160002331
    Abstract: The present invention provides for antibodies that bind to Notch1. The present disclosure also provides methods of making the antibodies, pharmaceutical compositions comprising these antibodies and methods of treating disorders with the antibodies and pharmaceutical compositions.
    Type: Application
    Filed: July 24, 2015
    Publication date: January 7, 2016
    Applicant: WYETH LLC
    Inventors: Kenneth G. GELES, Bin-Bing Stephen ZHOU, Lioudmila Gennadievna TCHISTIAKOVA, Yijie GAO, Joel BARD
  • Anti-Notch1 antibodies
    Patent number: 9127060
    Abstract: The present invention provides for antibodies that bind to Notch1. The present disclosure also provides methods of making the antibodies, pharmaceutical compositions comprising these antibodies and methods of treating disorders with the antibodies and pharmaceutical compositions.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: September 8, 2015
    Assignee: Wyeth LLC
    Inventors: Kenneth G. Geles, Bin-Bing Stephen Zhou, Lioudmila Gennadievna Tchistiakova, Yijie Gao, Joel Bard
  • CRYSTALLINE POLYMERIC COMPOSITIONS FOR OPHTHALMIC DEVICES
    Publication number: 20140277438
    Abstract: Ophthalmic devices suitable for implantation into the eye through small incisions or insertion into an existing orifice are disclosed. These devices are made from a composition comprising crystalline or semi-crystalline polymeric materials which have a glass transition temperature (Tg) of from about ?100° C. to about 37° C., and wherein Tg for the material is lower than Tm for the composition. Disclosed devices include intraocular lenses, corneal inlays, drug delivery devices and implants for reducing intraocular pressure in glaucoma patients.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 18, 2014
    Applicant: Medennium, Inc.
    Inventors: Christopher WILCOX, Christine Liau, Stephen Zhou, Igor Valyunin
  • ANTI-NOTCH3 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES
    Publication number: 20140127211
    Abstract: The present invention provides for anti-Notch3 antibodies, anti-Notch3 antibody-drug conjugates and methods for preparing and using the same.
    Type: Application
    Filed: November 6, 2013
    Publication date: May 8, 2014
    Applicant: Pfizer Inc.
    Inventors: Kenneth G. Geles, Yijie Gao, Puja Sapra, Lioudmila Gennadievna Tchistiakova, Bin-Bing Stephen Zhou
  • ANTI-NOTCH3 AGONIST ANTIBODIES AND THEIR USE IN THE TREATMENT OF NOTCH3-RELATED DISEASES
    Publication number: 20140093889
    Abstract: The present invention relates to agonist antibodies that specifically bind to Notch 3 and activate signaling. The present invention includes antibodies binding to an epitope comprising the first Lin12 domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
    Type: Application
    Filed: August 21, 2013
    Publication date: April 3, 2014
    Applicant: Genentech, Inc.
    Inventors: Kang Li, Bin-Bing Stephen Zhou, Wenjuan Wu, Sek Chung Fung, Sanjaya Singh
  • ANTI-NOTCH1 ANTIBODIES
    Publication number: 20130266594
    Abstract: The present invention provides for antibodies that bind to Notch1. The present disclosure also provides methods of making the antibodies, pharmaceutical compositions comprising these antibodies and methods of treating disorders with the antibodies and pharmaceutical compositions.
    Type: Application
    Filed: December 9, 2011
    Publication date: October 10, 2013
    Applicant: Wyeth LLC
    Inventors: Kenneth G. Geles, Bin-Bing Stephen Zhou, Lioudmila Gennadievna Tchistiakova, Yijie Gao, Joel Bard
  • Antagonist anti-Notch3 antibodies and their use in the prevention and treatment of Notch3-related diseases
    Patent number: 8329868
    Abstract: The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: December 11, 2012
    Assignee: Genentech, Inc.
    Inventors: Sek Chung Fung, Kang Li, Yucheng Li, Sanjaya Singh, Bin-Bing Stephen Zhou
  • ANTI-NOTCH3 AGONIST ANTIBODIES AND THEIR USE IN THE TREATMENT OF NOTCH3-RELATED DISEASES
    Publication number: 20120213785
    Abstract: The present invention relates to agonist antibodies that specifically bind to Notch 3 and activate signaling. The present invention includes antibodies binding to an epitope comprising the first Lin12 domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
    Type: Application
    Filed: April 23, 2012
    Publication date: August 23, 2012
    Applicant: Genentech, Inc.
    Inventors: Kang Li, Bin-Bing Stephen Zhou, Wenjuan Wu, Sek Chung Fung, Sanjaya Singh
  • Anti-notch3 agonist antibodies and their use in the treatment of notch3-related diseases
    Patent number: 8187839
    Abstract: The present invention relates to agonist antibodies that specifically bind to Notch 3 and activate signaling. The present invention includes antibodies binding to an epitope comprising the first Lin12 domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: May 29, 2012
    Assignee: Genentech, Inc.
    Inventors: Kang Li, Bin-Bing Stephen Zhou, Wenjuan Wu, Sek Chung Fung, Sanjaya Singh
  • ANTAGONIST ANTI-NOTCH3 ANTIBODIES AND THEIR USE IN THE PREVENTION AND TREATMENT OF NOTCH3-RELATED DISEASES
    Publication number: 20120114644
    Abstract: The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
    Type: Application
    Filed: January 18, 2012
    Publication date: May 10, 2012
    Applicant: Genentech, Inc.
    Inventors: Sek Chung Fung, Kang Li, Yucheng Li, Sanjaya Singh, Bin-Bing Stephen Zhou
  • Antagonist anti-Notch3 antibodies and their use in the prevention and treatment of Notch3-related diseases
    Patent number: 8148106
    Abstract: The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: April 3, 2012
    Assignee: Genentech, Inc.
    Inventors: Sek Chung Fung, Kang Li, Yucheng Li, Sanjaya Singh, Bin-Bing Stephen Zhou
  • ANTAGONIST ANTI-NOTCH3 ANTIBODIES AND THEIR USE IN THE PREVENTION AND TREATMENT OF NOTCH3-RELATED DISEASES
    Publication number: 20110223155
    Abstract: The present invention relates to antagonist antibodies that specifically bind to Notch 3 and inhibit its activation. The present invention includes antibodies binding to a conformational epitope comprising the first Lin12 domain and the second dimerization domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
    Type: Application
    Filed: February 8, 2011
    Publication date: September 15, 2011
    Inventors: Sek Chung Fung, Kang Li, Yucheng Li, Sanjaya Singh, Bin-Bing Stephen Zhou
  • ANTI-NOTCH3 AGONIST ANTIBODIES AND THEIR USE IN THE TREATMENT OF NOTCH3-RELATED DISEASES
    Publication number: 20110206675
    Abstract: The present invention relates to agonist antibodies that specifically bind to Notch 3 and activate signaling. The present invention includes antibodies binding to an epitope comprising the first Lin12 domain. The present invention also includes uses of these antibodies to treat or prevent Notch 3 related diseases or disorders.
    Type: Application
    Filed: February 23, 2011
    Publication date: August 25, 2011
    Applicant: Genentech, Inc.
    Inventors: KANG LI, Bin-Bing Stephen Zhou, Wenjuan Wu, Sek Chung Fung, Sanjaya Singh