Abstract: The present technology relates to depots for the treatment of postoperative pain via sustained, controlled release of a therapeutic agent. In some embodiments, the depot may comprise a therapeutic region comprising an analgesic, and a control region comprising a bioresorbable polymer and a releasing agent mixed with the polymer. The releasing agent may be configured to dissolve when the depot is placed in vivo to form diffusion openings in the control region. The depot may be configured to be implanted at a treatment site in vivo and, while implanted, release the therapeutic agent at the treatment site for no less than 3 days.

Abstract: Methods are disclosed for treating an autoimmune disorder in a subject in need thereof. These methods include administering to the subject a pharmaceutical preparation comprising isolated matrix bound vesicles (MBV) derived from extracellular matrix. The administration can be systemic. In some embodiments, the subject has rheumatoid arthritis or psoriasis.

Abstract: A system and method for operation of an autonomous vehicle (AV) yard truck is provided. A processor facilitates autonomous movement of the AV yard truck, and connection to and disconnection from trailers. A plurality of sensors are interconnected with the processor that sense terrain/objects and assist in automatically connecting/disconnecting trailers. A server, interconnected, wirelessly with the processor, that tracks movement of the truck around and determines locations for trailer connection and disconnection. A door station unlatches/opens rear doors of the trailer when adjacent thereto, securing them in an opened position via clamps, etc. The system computes a height of the trailer, and/or if landing gear of the trailer is on the ground and interoperates with the fifth wheel to change height, and whether docking is safe, allowing a user to take manual control, and optimum charge time(s). Reversing sensors/safety, automated chocking, and intermodal container organization are also provided.

Abstract: Described herein is a multi-user retail photo kiosk system that includes multiple touch screen and Graphic User Interface (GUI) controlled consumer photo editing, photo print and product selection, and photo order placement terminals and multiple photo printers. The user photo kiosk terminals can receive images. Billing and payment is accomplished using barcoded receipts provided at the user terminal for payments for purchased photo products. A printer array incorporating various printers capable of producing prints or various sizes and formats can be configured as a horizontal counter or as a vertical tower and includes means to alert the user that their photo print order is complete. In addition, the system automatically notifies operators if equipment service, maintenance, media refilling, and/or post printing finishing procedures are required.

Abstract: In some embodiments, an electronic device presents media items from different media applications in a unified media browsing application. In some embodiments, an electronic device facilitates browsing of media from different media applications based on category of media (e.g., movies, television shows, etc.). In some embodiments, an electronic device facilitates setup of a unified media browsing application that presents media items from different media applications in a unified media browsing user interface. In some embodiments, an electronic device displays multiple episodes of a collection of episodic content (e.g., a television series) in a user interface for the collection of episodic content. In some embodiments, an electronic device displays representations of, and provides access to, live-event media items accessible on the electronic device.

Abstract: A flavor or aroma charcoal material, such as charcoal briquets, which is formulated to include a flavor or aroma component. The charcoal material may include a smoldering agent (e.g., limestone), wood particles (e.g., sawdust), a binder, and the flavor or aroma component (herbs and/or spices). The flavor or aroma charcoal material may not be configured as a fuel charcoal material, for example, it may be substantially void of char and/or coal. In an embodiment, the flavor or aroma charcoal material may be provided as part of a blend of different charcoal materials that includes both flavor or aroma briquets in combination with fuel briquets (e.g., which fuel briquets include char and/or coal, while the flavor briquets do not). The flavor briquets provide enhanced aroma and/or flavor to the grilling experience.

Abstract: Composite parts (e.g. for implants) comprising fiber bundles including a plurality of aligned inorganic filaments, which are coated or impregnated with a polymer, and a polymeric matrix. The composite is stiff and ductile and preferably biodegradable and/or bioresorbable.

Abstract: A polymerizable compound is represented by the formula (I). Each R1 independently represents a monovalent group having from 3 to 12 carbon atoms that comprises at least one of an epoxy group, an acryl group, or a methacryl group. Each R2 independently represents H, F, Cl, Br, C1-C12 alkyl, C2-C3 carbonylalkyl, or C2-C5 carboalkoxy. Each R3 independently represents C H, F, Cl, Br, C1-C12 alkyl, C2-C3 carbonylalkyl, or C2-C5 carboalkoxy. Each n is independently 0, 1, 2, 3, or 4. Curable compositions including the polymerizable compound are also disclosed.

Abstract: Techniques are described for preserving the inflight sessions failing over from a primary database to the replicated logical database of the primary database. In an implementation, prior to failover, when the primary database server receives a commit for a transaction, the process stores a commit indication that the transaction has been committed by performing a corresponding SQL command. The commit indication is replicated to the logical replica database by virtue of the replication of the SQL command and its execution on the logical replica database. Accordingly, the standby database server in the failover session may successfully request for the outcome of the transaction. Techniques are also described for the client-side LOB references to be preserved when failing over to the logical replica database, for AS OF queries preserved, and for versioning of checksums, signatures and structures across logical replicas.

Abstract: Nucleotide sequences including a micro-dystrophin gene are provided. The micro-dystrophin genes may be operatively linked to a regulatory cassette. Methods of treating a subject having, or at risk of developing, muscular dystrophy, sarcopenia, heart disease, or cachexia are also provided. The methods may include administering a pharmaceutical composition including the micro-dystrophin gene and a delivery vehicle to a subject. Further, the methods may include administering the pharmaceutical composition a subject having Duchenne muscular dystrophy or Becker muscular dystrophy.

Abstract: A system is provided including a current sensor arranged to sense current drawn by an electric motor of a powered device through an AC power line from a power supply and provide current data related to the powered device; a monitoring device arranged to receive the current data from the electrical sensor, the monitoring device including a controller processing the current data to obtain performance data associated with the powered device, the performance data relating to load applied to the electric motor; a data communication device communicating with the monitoring device and arranged to receive the performance data associated with the powered device; and a computing device including a graphical user interface, the computer device receiving a user's selection of the powered device from a list of powered devices and presenting the performance data to the user via the graphical user interface in response to the user's selection.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A targeting system is disclosed. In use, the targeting system is configured to target (e.g., aim, locate, etc.) a fastener opening in a bone plate, more particularly, a variable angled fastener opening formed in a periphery of a periprosthetic bone plate. In one embodiment, the targeting system includes an alignment guide including a plurality of combo-slots for targeting a plurality of openings formed in the periprosthetic bone plate. In addition, the targeting system includes a plug configured to be positioned within the combo-slots formed in the alignment guide. In use, positioning the plug into the combo-slot formed in the alignment guide transforms the combo-slot into a substantially circular hole or opening with a predefined trajectory aligned with one of the variable angled openings formed in the periphery of the periprosthetic bone plate thereby defining a trajectory from the alignment guide to the variable angled opening.

Abstract: Disclosed are polymeric foamed compositions, foam padded materials that include such polymeric foamed compositions disposed on a sheet material, and packaging articles (e.g., envelopes) made from such foam padded materials. The polymeric foamed composition on the sheet material has a plurality of foamed structures formed from the foamable composition attached to the sheet material by a layer of the foamable composition, and the plurality foam structures each having a hollow core and a foam exterior shell.

Abstract: Methods for preparing a variety of bryostatin compounds are provided. The subject methods provide for preparation of bryostatin 1 in multi-gram quantities in a low and unprecedented number of convergent synthetic steps from commercially available materials. The subject methods are scalable with low estimated material costs and can provide enough material to meet clinical needs. Also provided are a variety of bryostatin analog compounds, and prodrug forms thereof, which are synthetically accessible via the subject methods and pharmaceutical compositions including the same.

Abstract: A composition includes n-acyl ethanolamine, at least one cannabinoid, and at least one terpene. The composition may be in the form of a tablet.

Abstract: Disclosed herein are methods and systems for rapid detection of antibiotic resistance of a microorganism in a sample. A modified recombinant phage is also disclosed which comprises an indicator gene in the late gene region. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.