Abstract: A nebulizer device includes an air intake port positioned downstream of a nebulizer element, and a mouthpiece positioned upstream of the nebulizer element. A flow sensor is coupled to a controller. The controller is configured to integrate an inhaled air flow signal received from the flow sensor for determining an inhaled air volume. The controller is also configured to turn on the nebulizer element when the inhaled air volume reaches a first predetermined threshold, and turn off the nebulizer element when the inhaled air volume reaches a second predetermined threshold. A method for targeted delivery of aerosolized particles to the lungs is also disclosed.

Abstract: A system for monitoring inspirable gas for delivery to a patient includes a branched breathing circuit having a first branch conduit and a second branch conduit. The first branch conduit is fluidly connected to a first gas source and the second branch conduit is fluidly connected to a second gas source, and the first and second branch conduits merge into a patient delivery conduit. The system includes a first flow sensor in the first branch conduit, a second flow sensor in the second branch conduit, and a third flow sensor in the patient delivery conduit. A control unit is electrically coupled to the first, second and third flow sensors. The control unit is configured to determine a blend of gas in the patient delivery circuit based on a measured flow from the third flow sensor and a measured flow from at least one of the first and second flow sensors.

Abstract: A veterinary subject intranasal administration device includes a first support member portion including a septum interface portion sized for insertion into a nasal passage of the veterinary subject; an actuation mechanism connected to the first support member portion; and a fluid conduit having a distal end opposite a supported end, the distal end sized for insertion into the nasal passage of the veterinary subject, the fluid conduit being flexible and configured to receive fluid from a fluid source and discharge the fluid through the distal end into the nasal passage, the distal end of the fluid conduit being unsupported and movable relative to the septum interface portion.

Abstract: Certain aspects of the present disclosure provide techniques for performing tabular convolution, including performing a tabularization operation on input data to generate a tabularized representation of the input data and performing a convolution operation using the tabularized representation of the input data to generate a convolution output.

Abstract: A dry powder inhaler dispenses a partial dosage of a powder from a dry powder chamber during a single user inhalation. In certain embodiments, the dry powder chamber is a dry powder capsule that spins in a chamber with a protrusion for limiting the spin of the capsule. In certain embodiments, a capsule slides in a proximal and distal direction for dispensing partial dosages of powder medicament. Air inlets in communication whit the external environment can be included in the inhaler housing for generating a smooth inhalation experience for the user and facilitating operation of partial dosage mechanisms. In other embodiments, a hinged member, sliding member, rotating member, spring tensioned member, pressure actuated valve, dry powder chamber with patterned holes or combinations of these are used as a mechanism for dispensing a partial dosage of powder medicament during a single inhalation.

Abstract: A method of reducing nicotine cravings is described. The method includes inhalation of a dry powder formulation containing a dose of nicotine by a subject seeking nicotine cravings reduction. The formulation includes amounts and concentrations of nicotine that are significantly lower than cigarettes or nicotine replacement therapies.

Abstract: The present invention provides dry powder inhaler (DPI) devices (100) for dispensing dry powder and methods for using the same. The DPI devices feature vortex mechanisms for directing air in a turbulent manner sufficient to entrain an amount of a dry powder dose for delivery into a user's lungs. The DPI devices feature replaceable dry powder cartridges (200). The DPI devices also feature a retractable configuration for storage and for accidental dispensing of dry powder. The DPI devices dispense dry powder in controlled dosages.

Abstract: Disclosed herein are a system, a method and a device for switching between different communications protocols. A head wearable display can transmit, to a console during a first session interval, a first request to switch from a first link using a first communication protocol to a second link using a second communication protocol. The first request can include at least one characteristic of the first link. The head wearable display can receive, from the console, a first response to the first request, to perform a switch from the first link to the second link. The first response can indicate a wake up time and a second session interval to perform the switch. The head wearable display can switch from the first link to the second link in the second session interval and after the wake up time.

Abstract: Disclosed herein are devices and methods related to an interface between a host processor and a wireless processor of a first device for maintaining an artificial reality session with a second device. In one aspect, the host processor is configured to provide data of the artificial reality session to the wireless processor, and the wireless processor is configured to transmit the data to the second device through a wireless medium. In one aspect, the host processor is configured to provide an indicator indicating an end of transmission of the data, to the wireless processor, to cause the wireless processor to transmit the indicator to the second device through the wireless medium, and to cause the host processor and the wireless processor to enter a sleep state in response to transmission of the indicator. The indicator may cause the second device to enter the sleep state.

Abstract: A device for accessing dry powder within a sealed chamber is described. The device includes a hollow housing having a proximal end opening, a primary distal end opening and a secondary distal end opening, at least one wing structure extending from the outer surface of the housing that is positioned distally from the primary distal opening. Also described is a dry powder inhaler having a housing, a penetrating component for accessing dry powder within a sealed chamber, and a mouthpiece, where the mouthpiece is connected to the proximal end opening of the penetrating component, and wherein the at least a portion of the distal end of the penetrating component is positioned within the inhaler housing.

Abstract: A device for adding a flavor and/or cough suppressant component to an inhaler is described. The device includes a housing having an interior chamber, wherein the housing includes at least one air inlet and at least one air outlet connected to the interior chamber, thereby forming an airflow pathway through the interior chamber, and at least one flavoring and/or cough suppressant component positioned within the interior chamber, wherein the housing is attachable to an exterior surface of an inhaler having at least one air inlet, such that the at least one air outlet of the device aligns with the at least one air inlet of the inhaler to form an airflow path through the device and into the inhaler.

Abstract: Described is a dry powder inhaler for inhalation of a dry powder composition. The inhaler includes an external housing that defines an internal passage. The inhaler also includes a mouthpiece, a compartment for holding a dry powder capsule or powder reservoir, and a powder fluidization and deagglomeration apparatus for directing airflow to the dry powder to generate airborne powder particles within the internal passage. When a user inhales through the mouthpiece, a first airflow pattern is generated that has a first airflow resistance, during which the fluidization and deagglomeration apparatus generates airborne dry powder particles within the internal passage. Upon reaching a threshold negative pressure value within the internal passage of the inhaler, a second airflow pattern is generated having a second airflow resistance that is lower than the first airflow resistance, which pulls the airborne dry powder into the user's lungs during the inhalation. Embodiments of elastomeric valves are also described.

Abstract: A veterinary subject intranasal administration device, and associated systems and methods, are disclosed. The veterinary subject intranasal administration device can include a first support member portion including a septum interface portion sized for insertion into a nasal passage of the veterinary subject; an actuation mechanism connected to the first support member portion; and a fluid conduit having a distal end opposite a supported end, the distal end sized for insertion into the nasal passage of the veterinary subject, the fluid conduit being flexible and configured to receive fluid from a fluid source and discharge the fluid through the distal end into the nasal passage, the distal end of the fluid conduit being unsupported and movable relative to the septum interface portion.

Abstract: A face mask includes an air-permeable body having a filter material having a proximal surface and a distal surface, the air-permeable body structurally configured for the proximal surface to cover the nose and mouth of a user when worn by the user, and a blower configured to generate a sub-peak inspiratory flow through the filter material.

Abstract: The present invention provides in part dry powder inhaler (DPI) devices for dispensing dry powder and methods for using the same. The DPI devices feature exchangeable cartridges having drum mechanisms that prepare metered doses of dry powder, and are able to direct air in a turbulent manner sufficient to entrain and deagglomerate a dose of dry powder for delivery into a user's lungs. The DPI devices feature a reservoir of dry powder advanced by a plunger, as well as a gauge that advances with the plunger to indicate the amount of dry powder remaining in the reservoir.

Abstract: The present invention provides devices (10) for holding one or more vapor sources in a media inhaler. The devices permit vapor from the one or more vapor sources to be introduced and entrained into a stream of inhaled media. The vapor insert device includes a hollow cylinder (12) having a porous surface (11), an open anterior end (9), and an open posterior end. An anterior flange (14) is attached to the open anterior end, and a posterior flange (16) is attached to the open posterior end. The anterior flange and the posterior flange each have a diameter that is larger than a diameter of the hollow cylinder to form a circumferential space around the hollow cylinder.

Abstract: The present invention provides dry powder formulations comprising nicotine, methods of using the same, and methods for making the same. The dry powder formulations may further comprise excipients, therapeutic agents, and flavor components. The dry powder formulations may be manufactured by dry processes and wet processes.

Abstract: A gas regulator is described. The gas regulator includes a gas inlet having an attachment mechanism for attaching to a gas container, a gas outlet in fluid communication with the gas inlet and further in fluid communication with a gas delivery system, a pressure regulator, a pressure sensor and a NFC sensor. A method of entering at least one information item relating to a gas source to a gas delivery system control unit. The method includes the steps of providing a gas source having a NFC tag that includes at least one information item stored in a memory of the NFC tag, attaching a regulator that includes a NFC sensor, wherein the NFC sensor is positioned to read the NFC tag when attached to the gas source, reading the at least one information item via the NFC sensor, and transmitting the at least one information item read by the NFC sensor to a gas delivery system control unit.