Abstract: A machining system including a first body with a first channel to receive a first stream of compressed air, a second channel to receive a second stream of compressed air, an upper compartment, the first stream of compressed air configured to clear debris from an upper compartment surface and a lower compartment surface when the first stream of compressed air is engaged, the upper compartment configured to shift to a position where the upper compartment abuts the lower compartment and conceals the upper compartment surface and the lower compartment surface when the second stream of compressed air is engaged, and the lower compartment configured to shift when in contact with the upper compartment.

Abstract: A method for estimating portal blood flow and hepatic function in a subject is provided. In one example, the STAT test is an in vitro simplified, convenient test intended for screening purposes that can reasonably estimate the portal blood flow from a single blood sample taken 60 minutes after orally administered deuterated-cholate. The test can be administered to a patient having, or suspected of having, Chronic Hepatitis C, Primary Sclerosing Cholangitis (PSC), Non-Alcoholic Fatty Liver Disease (NAFLD), or any chronic liver disease.

Abstract: A system may be configured to detect custom acoustic events, where the system generates an acoustic event profile for the custom acoustic event based on a natural language description provided by a user and using an audio sample of the described acoustic event. For example, the user may describe the custom acoustic event as “dog bark.” The system may ask the user questions to refine the description (e.g., dog breed, dog gender, age, etc.). Using an audio sample of the refined description, the system may then determine that audio captured in the user's environment is a potential sample of the custom acoustic event. Such captured audio may be presented to the user for confirmation, and then may be used to detect future occurrences of the custom acoustic event in the user's environment.

Abstract: In some examples, a non-transitory computer-readable medium stores machine-readable instructions which, when executed by a processor, cause the processor to cause a playback device to produce a sound using an audio file; cause a recording device to record the sound; compare the audio file to the recorded sound; determine, based on the comparison, whether the recorded sound comprises a noise not present in the audio file; and cause, based on the determination, a second recording device to be selected, a multiplexer to select a second playback device, or a combination thereof.

Abstract: A method for estimating portal blood flow and hepatic function in a subject is provided. In one example, the STAT test is an in vitro simplified, convenient test intended for screening purposes that can reasonably estimate the portal blood flow from a single blood sample taken 60 minutes after orally administered deuterated-cholate. The test can be administered to a patient having, or suspected of having, Chronic Hepatitis C, Primary Sclerosing Cholangitis (PSC), Non-Alcoholic Fatty Liver Disease (NAFLD), or any chronic liver disease.

Abstract: Simplified methods are provided for determining liver function based on a Compartmental Model (CM) method for analysis of various hepatic indices including cholate SHUNT test which closely approximates and elucidates the underlying physiology of hepatic uptake of cholate from systemic and portal circulations simultaneously.

Abstract: In some examples, a non-transitory computer-readable medium stores machine-readable instructions which, when executed by a processor, cause the processor to cause a playback device to produce a sound using an audio file; cause a recording device to record the sound; compare the audio file to the recorded sound; determine, based on the comparison, whether the recorded sound comprises a noise not present in the audio file; and cause, based on the determination, a second recording device to be selected, a multiplexer to select a second playback device, or a combination thereof.

Abstract: Methods are provided for determining liver function based on a Compartmental Model (CM) method for analysis of cholate SHUNT test data which closely approximates and elucidates the underlying physiology of hepatic uptake of cholate from systemic and portal circulations simultaneously.

Abstract: A machining system including a first body with a first channel to receive a first stream of compressed air, a second channel to receive a second stream of compressed air, an upper compartment, the first stream of compressed air configured to clear debris from an upper compartment surface and a lower compartment surface when the first stream of compressed air is engaged, the upper compartment configured to shift to a position where the upper compartment abuts the lower compartment and conceals the upper compartment surface and the lower compartment surface when the second stream of compressed air is engaged, and the lower compartment configured to shift when in contact with the upper compartment.

Abstract: In some examples, a non-transitory computer-readable medium stores machine-readable instructions which, when executed by a processor, cause the processor to cause a playback device to produce a sound using an audio file; cause a recording device to record the sound; compare the audio file to the recorded sound; determine, based on the comparison, whether the recorded sound comprises a noise not present in the audio file; and cause, based on the determination, a second recording device to be selected, a multiplexer to select a second playback device, or a combination thereof.

Abstract: The present disclosure provides systems and methods directed to a social-financial platform. In certain embodiments, sponsor-members, consumer-members, and beneficiary members are part of a social-financial platform in which purchases made by consumer-members at merchant sponsor-members result in automatic rebates being paid to and allocated between the consumer member and one or more beneficiary-members. Also disclosed is a monolithic financial structure for carrying out rebate allocation automatically and instantaneously, and for transferring funds between users.

Abstract: A Disease Severity Index (DSI) is provided for assessment of chronic liver disease in a patient using non-invasive liver function test results. A DSI was derived from non-invasive liver function test results based on hepatic blood flow. The DSI is used in methods for prediction of clinical outcomes, prediction of response to antiviral treatment, and assessment of progression of chronic liver diseases. Non-invasive methods to diagnose three distinct categories of patients with Primary Sclerosing Cholangitis (PSC) are provided. The methods can be used to diagnose PSC patients as Slow Progressors, Moderate Progressors and Rapid Progressors.

Abstract: A Disease Severity Index (DSI) is provided for assessment of chronic liver disease in a patient using non-invasive liver function test results. A DSI was derived from non-invasive liver function test results based on hepatic blood flow. The DSI is used in methods for prediction of clinical outcomes, prediction of response to antiviral treatment, and assessment of progression of chronic liver diseases. Non-invasive methods to diagnose three distinct categories of patients with Primary Sclerosing Cholangitis (PSC) are provided. The methods can be used to diagnose PSC patients as Slow Progressors, Moderate Progressors and Rapid Progressors.

Abstract: Improved methods and kits are provided for non-invasively evaluating liver function of a patient including rapidly and efficiently processing, detecting, and quantifying distinguishable compounds from patient blood or serum samples. A method is provided for estimating risk of experiencing a clinical event in 1 year for an individual patient having a chronic liver disease. Methods for determining hepatic reserve in a subject are provided.

Abstract: The present disclosure provides systems and methods directed to a social-financial platform. In certain embodiments, sponsor-members, consumer-members, and beneficiary members are part of a social-financial platform in which purchases made by consumer-members at merchant sponsor-members result in automatic rebates being paid to and allocated between the consumer member and one or more beneficiary-members. Also disclosed is a monolithic financial structure for carrying out rebate allocation automatically and instantaneously, and for transferring funds between users.

Abstract: A method for estimating portal blood flow and hepatic function in a subject is provided. In one example, the STAT test is an in vitro simplified, convenient test intended for screening purposes that can reasonably estimate the portal blood flow from a single blood sample taken 60 minutes after orally administered deuterated-cholate. The test can be administered to a patient having, or suspected of having, Chronic Hepatitis C, Primary Sclerosing Cholangitis (PSC), Non-Alcoholic Fatty Liver Disease (NAFLD), or any chronic liver disease.

Abstract: A method for estimating portal blood flow and hepatic function in a subject is provided. In one example, the STAT test is an in vitro simplified, convenient test intended for screening purposes that can reasonably estimate the portal blood flow from a single blood sample taken 60 minutes after orally administered deuterated-cholate. The test can be administered to a patient having, or suspected of having, Chronic Hepatitis C, Primary Sclerosing Cholangitis (PSC), Non-Alcoholic Fatty Liver Disease (NAFLD), or any chronic liver disease.

Abstract: The present disclosure provides systems and methods directed to a social-financial platform. In certain embodiments, sponsor-members, consumer-members, and beneficiary members are part of a social-financial platform in which purchases made by consumer-members at merchant sponsor-members result in automatic rebates being paid to and allocated between the consumer member and one or more beneficiary-members. Also disclosed is a monolithic financial structure for carrying out rebate allocation automatically and instantaneously, and for transferring funds between users.

Abstract: A Disease Severity Index (DSI) is provided for assessment of chronic liver disease in a patient using non-invasive liver function test results. A DSI was derived from non-invasive liver function test results based on hepatic blood flow. The DSI is used in methods for prediction of clinical outcomes, prediction of response to antiviral treatment, and assessment of progression of chronic liver diseases. Non-invasive methods to diagnose three distinct categories of patients with Primary Sclerosing Cholangitis (PSC) are provided. The methods can be used to diagnose PSC patients as Slow Progressors, Moderate Progressors and Rapid Progressors.

Abstract: A Disease Severity Index (DSI) is provided for assessment of chronic liver disease in a patient using non-invasive liver function test results. A DSI was derived from non-invasive liver function test results based on hepatic blood flow. The DSI is used in methods for prediction of clinical outcomes, prediction of response to antiviral treatment, and assessment of progression of chronic liver diseases. Non-invasive methods to diagnose three distinct categories of patients with Primary Sclerosing Cholangitis (PSC) are provided. The methods can be used to diagnose PSC patients as Slow Progressors, Moderate Progressors and Rapid Progressors.