Patents by Inventor Steven A. Kates

Steven A. Kates has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF
    Publication number: 20230399355
    Abstract: Antimicrobial compounds and compositions of Formulas (V), (VI), (VII), (VIII), and (IX), and methods of use are disclosed.
    Type: Application
    Filed: August 28, 2023
    Publication date: December 14, 2023
    Inventors: Steven A. Kates, Randolph B. Sleet, Steven Parkinson
  • Antimicrobial compounds, compositions, and uses thereof
    Patent number: 11795192
    Abstract: Antimicrobial compounds and compositions of Formulas (V), (VI), (VII), (VIII), and (IX), and methods of use are disclosed.
    Type: Grant
    Filed: August 17, 2022
    Date of Patent: October 24, 2023
    Assignee: Lakewood Amedex, Inc.
    Inventors: Steven A. Kates, Randolph B. Sleet, Steven Parkinson
  • BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF
    Publication number: 20230125677
    Abstract: Gel formulations having antimicrobial activity are disclosed. Methods of using the gel formulation are further disclosed.
    Type: Application
    Filed: December 16, 2022
    Publication date: April 27, 2023
    Inventors: Steven A. Kates, PhD, Keith Arthur Johnson
  • ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF
    Publication number: 20230026056
    Abstract: Antimicrobial compounds and compositions of Formulas (V), (VI), (VII), (VIII), and (IX), and methods of use are disclosed.
    Type: Application
    Filed: August 17, 2022
    Publication date: January 26, 2023
    Inventors: Steven A. Kates, Randolph B. Sleet, Steven Parkinson
  • ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF
    Publication number: 20220348605
    Abstract: A method of treating an infection of a lung in a patient in need thereof according to an embodiment includes administering to the patient an effective amount of a compound having the formula: or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: July 1, 2022
    Publication date: November 3, 2022
    Inventors: Randolph B. Sleet, Steven A. Kates, Steven Parkinson
  • Compositions And Methods For Treating Traumatic Brain Injury
    Publication number: 20220280477
    Abstract: The present invention relates, in certain embodiments, to methods for preventing and/or treating neurodegenerative damage (e.g., secondary cascade of neurodegenerative damage) and improving functional outcomes (e.g., outcomes associated with cognitive, behavior and sensorimotor function) caused by traumatic brain injury (TBI) using neuroprotective lipoyl compounds. The present invention also provides, in various embodiments, compositions for use in treating and/or preventing TBI in a subject in need thereof, compounds for use in the manufacture of a medicament for treating and/or preventing TBI in a subject in need thereof, and methods of preparing a pharmaceutical composition for treating and/or preventing secondary brain damage caused by TBI.
    Type: Application
    Filed: December 15, 2021
    Publication date: September 8, 2022
    Inventors: Alexander Baguisi, Reinier Beeuwkes, Ralph Casale, David A. DeWahl, JR., Steven A. Kates, Alan S. Lader
  • Antimicrobial compounds, compositions, and uses thereof
    Patent number: 11377468
    Abstract: A method of treating an infection of at least one of a wound or a ulcer in a patient in need thereof according to an embodiment includes administering to the patient an effective amount of a compound having the formula: or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 19, 2021
    Date of Patent: July 5, 2022
    Assignee: Lakewood Amedex, Inc.
    Inventors: Randolph B. Sleet, Steven A. Kates, Steven Parkinson
  • Compositions and methods for treating traumatic brain injury
    Patent number: 11213509
    Abstract: The present invention relates, in certain embodiments, to methods for preventing and/or treating neurodegenerative damage (e.g., secondary cascade of neurodegenerative damage) and improving functional outcomes (e.g., outcomes associated with cognitive, behavior and sensorimotor function) caused by traumatic brain injury using neuroprotective lipoyl compounds. The present invention also provides, in various embodiments, compositions for use in treating and/or preventing TBI in a subject in need thereof, compounds for use in the manufacture of a medicament for treating and/or preventing TBI in a subject in need thereof, and methods of preparing a pharmaceutical composition for treating and/or preventing secondary brain damage caused by TBI.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: January 4, 2022
    Assignee: ISCHEMIX, LLC
    Inventors: Alexander Baguisi, Reinier Beeuwkes, Ralph Casale, David A. DeWahl, Jr., Steven A. Kates, Alan S. Lader
  • METHODS AND COMPOSITIONS FOR TREATING ORAL MUCOSITIS
    Publication number: 20210393666
    Abstract: Methods and pharmaceutical compositions including Bisphosphocins for treating oral mucositis in a patient are disclosed.
    Type: Application
    Filed: August 27, 2021
    Publication date: December 23, 2021
    Inventors: Steven A. Kates, Steven Parkinson, Patrick C. O'Connor
  • BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF
    Publication number: 20210361689
    Abstract: Gel formulations having antimicrobial activity are disclosed. Methods of using the gel formulation are further disclosed.
    Type: Application
    Filed: August 9, 2021
    Publication date: November 25, 2021
    Inventors: Steven A. Kates, Keith Arthur Johnson
  • Methods and compositions for treating oral mucositis
    Patent number: 11123357
    Abstract: Methods and pharmaceutical compositions including Bisphosphocins for treating oral mucositis in a patient are disclosed.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: September 21, 2021
    Assignee: Lakewood Amedex, Inc.
    Inventors: Steven A. Kates, Steven Parkinson, Patrick C. O'Connor
  • Bisphosphocin gel formulations and uses thereof
    Patent number: 11096954
    Abstract: Gel formulations including a Bisphosphocin having antimicrobial activity are disclosed. Methods of using the gel formulations including a Bisphosphocin are further disclosed.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: August 24, 2021
    Assignee: Lakewood Amedex, Inc.
    Inventors: Steven A. Kates, Keith Arthur Johnson
  • ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF
    Publication number: 20210238215
    Abstract: A method of treating an infection of at least one of a wound or a ulcer in a patient in need thereof according to an embodiment includes administering to the patient an effective amount of a compound having the formula: or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 19, 2021
    Publication date: August 5, 2021
    Inventors: Randolph B. Sleet, PhD, Steven A. Kates, PhD, Steven Parkinson
  • ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF
    Publication number: 20210139522
    Abstract: Antimicrobial compounds and compositions of Formulas (I) to (III) and methods of use are disclosed. Another aspect of the present disclosure provides a pharmaceutical composition comprising a compound according to Formula (I) to (III), or a pharmaceutically acceptable salt thereof, and one or more pharmaceutically acceptable carriers, excipients, or diluents. Another aspect of the present disclosure provides a method of treating a bacterial infection in a patient in need thereof, the method of comprising administering an effective amount of a compound according to Formula (I) to (III), or a pharmaceutically acceptable salt thereof, to the patient.
    Type: Application
    Filed: March 12, 2018
    Publication date: May 13, 2021
    Inventors: Steven A. Kates, Randolph B. Sleet, Steven Parkinson
  • Antimicrobial compounds, compositions, and uses thereof
    Patent number: 10981943
    Abstract: Antimicrobial compounds and compositions of Formula (I) and methods of use are disclosed.
    Type: Grant
    Filed: July 29, 2020
    Date of Patent: April 20, 2021
    Assignee: Lakewood Amedex, Inc.
    Inventors: Randolph B. Sleet, Steven A. Kates, Steven Parkinson
  • Implantable meshes for controlling the movement of fluids
    Patent number: 10869907
    Abstract: Meshes for use to control the movement of bodily fluids, such as blood, are described herein. The mesh can be partially or completely biodegradable or non-biodegradable. In one embodiment, the mesh is formed from one or more self-assembling peptides. The peptides can be in the form of fibers, such as nanofibers. The peptides can be assembled prior to formation of the mesh or after the mesh has been formed but before it is applied. Alternatively, the mesh can be prepared from unassembled peptides, which assemble at the time of application. The peptides can assemble upon contact with bodily fluids (e.g., blood) or can be contacted with an ionic solution to initiate assembly.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: December 22, 2020
    Assignee: ARCH BIOSURGERY, INC.
    Inventors: Terrence Norchi, Steven Kates, Rutledge Ellis-Behnke
  • BISPHOSPHOCIN GEL FORMULATIONS AND USES THEREOF
    Publication number: 20200360415
    Abstract: Gel formulations having antimicrobial activity are disclosed. Methods of using the gel formulation are further disclosed.
    Type: Application
    Filed: July 30, 2020
    Publication date: November 19, 2020
    Inventors: Steven A. Kates, Keith Arthur Johnson
  • Compositions And Methods For Treating Traumatic Brain Injury
    Publication number: 20200352904
    Abstract: The present invention relates, in certain embodiments, to methods for preventing and/or treating neurodegenerative damage (e.g., secondary cascade of neurodegenerative damage) and improving functional outcomes (e.g., outcomes associated with cognitive, behavior and sensorimotor function) caused by traumatic brain injury using neuroprotective lipoyl compounds. The present invention also provides, in various embodiments, compositions for use in treating and/or preventing TBI in a subject in need thereof, compounds for use in the manufacture of a medicament for treating and/or preventing TBI in a subject in need thereof, and methods of preparing a pharmaceutical composition for treating and/or preventing secondary brain damage caused by TBI.
    Type: Application
    Filed: July 30, 2020
    Publication date: November 12, 2020
    Inventors: Alexander Baguisi, Reinier Beeuwkes, Ralph Casale, David A. DeWahl, JR., Steven A. Kates, Alan S. Lader
  • ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF
    Publication number: 20200354395
    Abstract: Antimicrobial compounds and compositions of Formula (I) and methods of use are disclosed.
    Type: Application
    Filed: July 29, 2020
    Publication date: November 12, 2020
    Inventors: Randolph B. Sleet, Steven A. Kates, Steven Parkinson
  • Antimicrobial compounds, compositions, and uses thereof
    Patent number: 10752651
    Abstract: Antimicrobial compounds and compositions of Formula (I) and methods of use are disclosed.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: August 25, 2020
    Assignee: Lakewood Amedex, Inc.
    Inventors: Randolph B. Sleet, Steven A. Kates, Steven Parkinson