Patents by Inventor Steven A. Kates

Steven A. Kates has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8772249
    Abstract: The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula I: and methods of using such compounds to activate cytoprotective kinases. The values and preferred values of the variables in Structural Formula I are defined herein.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: July 8, 2014
    Assignee: Ischemix, LLC
    Inventors: Alexander Baguisi, Reinier Beeuwkes, Ralph Casale, Steven A. Kates, Alan Lader
  • Publication number: 20130237483
    Abstract: The present invention relates, in various embodiments, to a compound represented by Structural Formula (I), pharmaceutically acceptable salts or prodrugs thereof, and compositions comprising said compounds, or pharmaceutically acceptable salts or prodrugs thereof. Methods of using compounds of Structural Formulas (I) and (la) or compositions comprising compounds of Structural Formulas (I) and (la), or pharmaceutically acceptable salts or prodrugs thereof, to treat ischemia or ischemia-reperfusion injury are also disclosed.
    Type: Application
    Filed: November 10, 2011
    Publication date: September 12, 2013
    Inventors: Alexander B. Baguisi, Reinier Beeuwkes, Ralph Casale, Steven A. Kates, Alan S. Lader
  • Publication number: 20120135932
    Abstract: The present invention relates, in some embodiments, to compositions comprising a substantially pure compound represented by Structural Formula (I) and methods of using such compounds to activate cytoprotective kinases. In additional embodiments, the invention relates to methods for treating an ischemia or an ischemia-reperfusion injury in a subject, comprising administering to the subject an effective amount of a compound of the invention (e.g., in multiple doses). The values and preferred values of the variables in Structural Formula (I) are defined herein.
    Type: Application
    Filed: May 13, 2010
    Publication date: May 31, 2012
    Inventors: Alexander B. Baguisi, Reinier Beeuwkes, Ralph Casale, Steven A. Kates, Alan S. Lader
  • Publication number: 20110160294
    Abstract: The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula I: and methods of using such compounds to activate cytoprotective kinases. The values and preferred values of the variables in Structural Formula I are defined herein.
    Type: Application
    Filed: March 4, 2011
    Publication date: June 30, 2011
    Applicant: Ischemix LLC
    Inventors: Alexander Baguisi, Reinier Beeuwkes, Ralph Casale, Steven A. Kates, Alan Lader
  • Patent number: 7928067
    Abstract: The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula II: and methods of using such compounds to activate cytoprotective kinases.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: April 19, 2011
    Assignee: Ischemix LLC
    Inventors: Alexander Baguisi, Reinier Beeuwkes, Ralph Casale, Steven A. Kates, Alan Lader
  • Publication number: 20100292313
    Abstract: The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula II: and methods of using such compounds to activate cytoprotective kinases.
    Type: Application
    Filed: May 14, 2009
    Publication date: November 18, 2010
    Inventors: Alexander Baguisi, Reinier Beeuwkes, Ralph Casale, Steven A. Kates, Alan Lader
  • Publication number: 20030167129
    Abstract: Binding compounds for CXC chemokine receptor 4 and methods for identifying binding compounds for CXC chemokine receptor 4 are provided. Also provided are therapeutic agents comprising such compounds.
    Type: Application
    Filed: October 26, 2001
    Publication date: September 4, 2003
    Inventors: John J. Nestor, Carol J. Wilson, Christina A. Tan Hehir, Steven A. Kates, John Krstenansky
  • Publication number: 20030018438
    Abstract: Compositions of binding compounds for CXC chemokine receptor 4 and methods for identifying binding compounds for CXC chemokine receptor 4 are provided. Also provided are therapeutic agents comprising such compounds.
    Type: Application
    Filed: March 20, 2001
    Publication date: January 23, 2003
    Inventors: John J. Nestor, Carol J. Wilson, Christina A. Tan Hehir, Steven A. Kates
  • Patent number: 5861351
    Abstract: A method for removing an allyl protecting group from an allyl-protected derivative of a biologically relevant amino acid is disclosed. One relevant aspect of the method is the use of soluble organometallic catalyst, such as an organopalladium catalyst. Preferably, soluble tetrakistriphenylphosphine palladium (0) is used. The allyl deprotection method now disclosed is suitable for use on an instrument for automated peptide synthesis. Methods of preparing the soluble organometallic catalyst are also disclosed, as are soluble catalyst compositions.
    Type: Grant
    Filed: September 20, 1996
    Date of Patent: January 19, 1999
    Assignee: PerSeptive Biosystems, Inc.
    Inventors: Fernando Albericio, Steven A. Kates
  • Patent number: 5777077
    Abstract: A method for removing an allyl protecting group from an allyl-protected derivative of a biologically relevant amino acid is disclosed. One relevant aspect of the method is the use of soluble organometallic catalyst, such as an organopalladium catalyst. Preferably, soluble tetrakistriphenylphosphine palladium (0) is used. The allyl deprotection method now disclosed is suitable for use on an instrument for automated peptide synthesis. Methods of preparing the soluble organometallic catalyst are also disclosed, as are soluble catalyst compositions.
    Type: Grant
    Filed: February 20, 1997
    Date of Patent: July 7, 1998
    Assignee: PerSeptive Biosystems, Inc.
    Inventors: Fernando Albericio, Steven A. Kates