Patents by Inventor Steven David Knight

Steven David Knight has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080300239
    Abstract: Invented is a method of inhibiting the activity/function of PI3 kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives.
    Type: Application
    Filed: May 16, 2008
    Publication date: December 4, 2008
    Inventors: Nicholas D. Adams, Joelle Lorraine Burgess, Michael Gerrard Darcy, Carla A. Donatelli, Steven David Knight, Kenneth Allen Newlander, Lance Ridgers, Martha A. Sarpong, Stanley J. Schmidt
  • Publication number: 20080293706
    Abstract: Invented is a method of inhibiting the activity/function of PI3 kinases using quinoxaline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoxaline derivatives.
    Type: Application
    Filed: May 8, 2008
    Publication date: November 27, 2008
    Inventors: Amita CHAUDHARI, Dashyant DHANAK, Carla Ann DONATELLI, Thomas H. FAITG, Yanhong FENG, Steven David KNIGHT, Cynthia A. PARRISH, Jeffrey M. RALPH
  • Publication number: 20080255115
    Abstract: Invented is a method of inhibiting the activity/function of PI3 kinases using thiazolidinedione derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of thiazolidinedione derivatives.
    Type: Application
    Filed: August 24, 2007
    Publication date: October 16, 2008
    Inventors: Michael Gerard Darcy, Steven David Knight, Nicholas D. Adams, Stanley J. Schmidt
  • Publication number: 20080176830
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: April 13, 2006
    Publication date: July 24, 2008
    Inventors: Nicholas D. Adams, Michael Gerard Darcy, Dashyant Dhanak, Kevin J. Duffy, Duke M. Fitch, Steven David Knight, Kenneth Allen Newlander, Antony N. Shaw
  • Patent number: 7332498
    Abstract: A method of modulating KSP kinesin activity in vitro comprising contacting KSP kinesin with at least one chemical entity chosen from compounds represented by Formula I: and pharmaceutically acceptable salts thereof, where the variables are as defined further herein.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: February 19, 2008
    Assignees: Cytokinetics, Inc., SmithKline Beecham Corporation
    Inventors: Pu-Ping Lu, David J. Morgans, Jr., Bing Yao, Dashyant Dhanak, Steven David Knight
  • Patent number: 7214800
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Grant
    Filed: May 8, 2003
    Date of Patent: May 8, 2007
    Assignees: Cytokinetics, Inc., Smithkline Beecham Corporation
    Inventors: Bainian Feng, Gustave Bergnes, David J. Morgans, Jr., Dashyant Dhanak, Steven David Knight, Michael Gerard Darcy
  • Patent number: 7208487
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: April 24, 2007
    Assignee: Cytokinetics, Incorporated
    Inventors: Gustave Bergnes, Dashyant Dhanak, Steven David Knight, Pu Ping Lu, David J. Morgans, Jr., Kenneth Allen Newlander
  • Patent number: 7166595
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Grant
    Filed: May 2, 2003
    Date of Patent: January 23, 2007
    Assignees: Cytokinetics, Inc., SmithKline Beecham Corporation
    Inventors: Han-Jie Zhou, David J. Morgans, Jr., Gustave Bergnes, Steven David Knight, Kenneth A. Newlander, Dashyant Dhanak, Nicholas D. Adams
  • Patent number: 7041676
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Grant
    Filed: June 12, 2003
    Date of Patent: May 9, 2006
    Assignees: Cytokinetics, Inc., Smithkline Beecham Corporation
    Inventors: Andrew McDonald, Pu-Ping Lu, Gustave Bergnes, David J. Morgans, Jr., Dashyant Dhanak, Steven David Knight
  • Patent number: 7038048
    Abstract: Provided herein are certain compounds of Formula I: that can be used to treat diseases of proliferating cells. The compounds are KSP kinesin inhibitors, particularly inhibitors of human KSP.
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: May 2, 2006
    Assignees: Cytokinetics, Inc., SmithKline Beecham Corporation
    Inventors: Pu-Ping Lu, David J. Morgans, Jr., Bing Yao, Dashyant Dhanak, Steven David Knight
  • Patent number: 6949538
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Grant
    Filed: July 17, 2003
    Date of Patent: September 27, 2005
    Assignees: Cytokinetics, Inc., Smithkline Beecham Corporation
    Inventors: Andrew McDonald, Gustave Bergnes, David J. Morgans, Jr., Dashyant Dhanak, Steven David Knight
  • Patent number: 6924376
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: August 2, 2005
    Assignees: Cytokinetics, Inc., Smithkline Beecham Corporation
    Inventors: Andrew McDonald, Gustave Bergnes, Bainian Feng, David J. Morgans, Jr., Steven David Knight, Kenneth A. Newlander, Dashyant Dhanak, Christopher A. Brook
  • Publication number: 20040116438
    Abstract: Compounds, compositions and methods useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: May 22, 2003
    Publication date: June 17, 2004
    Inventors: Pu-Ping Lu, David J. Morgans, Bing Yao, Dashyant Dhanak, Steven David Knight
  • Publication number: 20040116400
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: July 17, 2003
    Publication date: June 17, 2004
    Applicants: CYTOKINETICS, INC., SMITHKLINE BEECHAM CORPORATION
    Inventors: Andrew McDonald, Gustave Bergnes, David J. Morgans, Dashyant Dhanak, Steven David Knight
  • Publication number: 20040082567
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: June 12, 2003
    Publication date: April 29, 2004
    Applicants: Cytokinetics, Inc., Smithkline Beecham Corporation
    Inventors: Andrew McDonald, Pu-Ping Lu, Gustave Bergnes, David J. Morgans, Dashyant Dhanak, Steven David Knight
  • Publication number: 20040082638
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: April 11, 2003
    Publication date: April 29, 2004
    Applicant: Cytokinetics, Inc.
    Inventors: Andrew McDonald, Gustave Bergnes, Bainian Feng, David J. Morgans, Steven David Knight, Kenneth A. Newlander, Dashyant Dhanak, Christopher A. Brook
  • Publication number: 20040077662
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: May 2, 2003
    Publication date: April 22, 2004
    Applicant: Cytokinetics, Inc.
    Inventors: Han-Jie Zhou, David J. Morgans, Gustave Bergnes, Steven David Knight, Kenneth A. Newlander, Dashyant Dhanak, Nicholas D. Adams
  • Publication number: 20040077668
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: May 8, 2003
    Publication date: April 22, 2004
    Applicants: Cytokinetics, Inc., SmithKline Beecham
    Inventors: Bainian Feng, Gustave Bergnes, David J. Morgans, Dashyant Dhanak, Steven David Knight, Michael Gerard Darcy
  • Publication number: 20030100580
    Abstract: P51084 The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.
    Type: Application
    Filed: June 13, 2002
    Publication date: May 29, 2003
    Inventors: Dashyant Dhanak, Steven David Knight
  • Patent number: 6544992
    Abstract: The present invention relates to pyrrolyl and pyridyl derivatives, pharmaceutical compositions containing them and their use as inhibitors of urotensin II.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: April 8, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Dashyant Dhanak, Steven David Knight, Jian Jin, Richard McCulloch Keenan