Abstract: Systems and methods for isolating applications associated with multiple tenants within a computing platform receive a request from a client associated with a tenant for running an application on a computing platform. Hosts connected to the platform are associated with a network address and configured to run applications associated with multiple tenants. A host is identified based at least in part on the request. One or more broadcast domain(s) including the identified hosts are generated. The broadcast domains are isolated in the network at a data link layer. A unique tenant identification number corresponding to the tenant is assigned to the broadcast domains. In response to launching the application on the host: the unique tenant identification number is assigned to the launched application and is added to the network address of the host; and the network address of the host is sent to the client associated with the tenant.

Abstract: A parking brake system is disclosed and includes one or more pressure transducers that monitor the fluid pressure of the parking brake system and a brake selection device configured to indicate the parking brake system is either in an engaged state or a disengaged state. The parking brake system includes one or more processors and a memory coupled to the one or more processors. The memory stores data comprising a database and program code that, when executed by the one or more processors, causes the parking brake system to determine the fluid pressure of the parking brake system is less than a threshold pressure. In response to determining the fluid pressure of the parking brake system is less than the threshold pressure, the parking brake system instructs the brake selection device to indicate the parking brake system is in the disengaged state.

Abstract: An electronic device may access one or more records associated with an individual based at least in part on an identifier of the individual. Then, based at least in part on values of features associated with a predetermined segment in a population that includes the individual and values of the features in the one or more records, the electronic device assigns the individual to the predetermined segment. Note that the features may be identified based at least in part on count statistics of the features in combinations of features for the population, and the predetermined segment may be based at least in part on distances (such as Euclidean distances) computed using values of the features. Next, the electronic device provides a recommendation for the individual, where the recommendation is based at least in part on one or more attributes associated with one or more other individuals in the predetermined segment.

Abstract: The present disclosure features signal-regulatory protein ? (SIRP-?) polypeptides and constructs that are useful, e.g., to target a cell (e.g., a cancer cell or a cell of the immune system), to increase phagocytosis of the target cell, to eliminate immune cells such as regulatory T-cells, to kill cancer cells, to treat a disease (e.g., cancer) in a subject, or any combinations thereof. The SIRP-? constructs include a high affinity SIRP-? D1 domain or variant thereof that binds CD47 with higher affinity than a wild-type SIRP-?. The SIRP-? polypeptides or constructs include a SIRP-? D1 variant fused to an Fc domain monomer, a human serum albumin (HSA), an albumin-binding peptide, or a polyethylene glycol (PEG) polymer. Compositions provided herein include (i) a polypeptide including a signal-regulatory protein ? (SIRP-?) D1 variant and (ii) an antibody.

Abstract: An integrated circuit for use in a first vehicle may include: an interface circuit that communicates with a second integrated circuit in a second vehicle; and a processing circuit. During operation, the processing circuit may determine that the second vehicle has better situational awareness for a portion of a road or an environment proximate to the road than the first vehicle, where the second vehicle is proximate to the first vehicle. Then, the processing circuit may dynamically establish, with the second integrated circuit, a communication pairing with the second vehicle. Moreover, the integrated circuit may exchange, via the pairing, information with the second integrated circuit. For example, the exchanged information may include or may specify: measurement data, one or more detected objects, one or more object identifiers, seed information for a detection technique (such as a priori information), and/or a priority or urgency of the exchanged information.

Abstract: Provided herein, inter alia, are isolated antibodies that bind an extracellular domain of a human SIRP-? v1 polypeptide (e.g., the D1 domain), an extracellular domain of a human SIRP-? v2 polypeptide, or both. In some embodiments, the antibodies also bind an extracellular domain of a monkey SIRP-? polypeptide, an extracellular domain of a mouse SIRP-? polypeptide, an extracellular domain of a human SIRP-? polypeptide, and/or an extracellular domain of a human SIRP-? polypeptide. In some embodiments, the antibodies block or do not binding between an extracellular domain of a human SIRP-? polypeptide and an IgSF domain of a human CD47 polypeptide, while in some embodiments, the antibodies reduce the affinity of a human SIRP-? polypeptide for binding an IgSF domain of a human CD47 polypeptide. Further provided herein are methods, polynucleotides, vectors, and host cells related thereto.

Abstract: A brake system for a vehicle is disclosed and includes an energy storage device configured to store and discharge energy, a plurality of wheels having an observer wheel, one or more processors operatively coupled to the energy storage device, and a memory coupled to the one or more processors. The memory stores data comprising a database and program code that, when executed by the one or more processors, causes the brake system to determine the brake system is operating in a backup mode of operation. In response to determining the brake system is operating in the backup mode of operation, the brake system is caused to apply a first brake pressure command to the observer wheel. In response to determining the observer wheel is starting the skid condition, the brake system is caused to determine a second brake pressure command based on a target slip value.

Abstract: Brake control systems are disclosed herein. A brake control system comprises a first set of analog-to-digital converters in electrical communication with a first set of brake input mechanism sensors and a second set of analog-to-digital converters in electrical communication with a second set of brake input mechanism sensors. The first and second sets of analog-to-digital converters comprise one or more of different hardware and different software for differentially manipulating sensor outputs received from the brake input mechanism sensors.

Abstract: Provided herein, inter alia, are isolated antibodies that bind an extracellular domain of a human SIRP-? v1 polypeptide (e.g., the D1 domain), an extracellular domain of a human SIRP-? v2 polypeptide, or both. In some embodiments, the antibodies also bind an extracellular domain of a monkey SIRP-? polypeptide, an extracellular domain of a mouse SIRP-? polypeptide, an extracellular domain of a human SIRP-? polypeptide, and/or an extracellular domain of a human SIRP-? polypeptide. In some embodiments, the antibodies block or do not binding between an extracellular domain of a human SIRP-? polypeptide and an IgSF domain of a human CD47 polypeptide, while in some embodiments, the antibodies reduce the affinity of a human SIRP-? polypeptide for binding an IgSF domain of a human CD47 polypeptide. Further provided herein are methods, polynucleotides, vectors, and host cells related thereto.

Abstract: A brake system includes a brake stack having a stack closure pressure, a force member positioned within a cylinder, a valve configured to control fluid pressure of the brake system, and one or more pressure transducers that generate a proportional electrical signal representative of the fluid pressure within the cylinder. The brake system also includes one or more processors in electronic communication with the valve, the one or more pressure transducers, and a memory coupled to the one or more processors. The memory stores data comprising a database and program code that, when executed by the one or more processors, causes the brake system to determine the stack closure pressure of the brake stack.

Abstract: A brake system for a vehicle is disclosed and includes an energy storage device configured to store and discharge energy, a plurality of wheels, one or more processors operatively coupled to the energy storage device, and a memory coupled to the one or more processors. The memory stores data comprising a database and program code that, when executed by the one or more processors, causes the brake system to determine the brake system is operating in a backup mode of operation. In response to determining the brake system is operating in the backup mode of operation, the brake system calculates a dynamic slip of the plurality of wheels. The brake system is caused to determine a slip error by comparing the dynamic slip with a target slip value of the plurality of wheels. The brake system is also caused to calculate an antiskid command based on the slip error.

Abstract: Provided herein, inter alia, are isolated antibodies that bind an extracellular domain of a human SIRP-? v1 polypeptide (e.g., the D1 domain), an extracellular domain of a human SIRP-? v2 polypeptide, or both. In some embodiments, the antibodies also bind an extracellular domain of a monkey SIRP-? polypeptide, an extracellular domain of a mouse SIRP-? polypeptide, an extracellular domain of a human SIRP-? polypeptide, and/or an extracellular domain of a human SIRP-? polypeptide. In some embodiments, the antibodies block or do not binding between an extracellular domain of a human SIRP-? polypeptide and an IgSF domain of a human CD47 polypeptide, while in some embodiments, the antibodies reduce the affinity of a human SIRP-? polypeptide for binding an IgSF domain of a human CD47 polypeptide. Further provided herein are methods, polynucleotides, vectors, and host cells related thereto.

Abstract: Provided herein, inter alia, are isolated antibodies that bind an extracellular domain of a human SIRP-? v1 polypeptide (e.g., the D1 domain), an extracellular domain of a human SIRP-? v2 polypeptide, or both. In some embodiments, the antibodies also bind an extracellular domain of a monkey SIRP-? polypeptide, an extracellular domain of a mouse SIRP-? polypeptide, an extracellular domain of a human SIRP-? polypeptide, and/or an extracellular domain of a human SIRP-? polypeptide. In some embodiments, the antibodies block or do not binding between an extracellular domain of a human SIRP-? polypeptide and an IgSF domain of a human CD47 polypeptide, while in some embodiments, the antibodies reduce the affinity of a human SIRP-? polypeptide for binding an IgSF domain of a human CD47 polypeptide. Further provided herein are methods, polynucleotides, vectors, and host cells related thereto.

Abstract: The present disclosure features signal-regulatory protein ? (SIRP-?) polypeptides and constructs that are useful, e.g., to target a cell (e.g., a cancer cell or a cell of the immune system), to increase phagocytosis of the target cell, to eliminate immune cells such as regulatory T-cells, to kill cancer cells, to treat a disease (e.g., cancer) in a subject, or any combinations thereof. The SIRP-? constructs include a high affinity SIRP-? D1 domain or variant thereof that binds CD47 with higher affinity than a wild-type SIRP-?. The SIRP-? polypeptides or constructs include a SIRP-? D1 variant fused to an Fc domain monomer, a human serum albumin (HSA), an albumin-binding peptide, or a polyethylene glycol (PEG) polymer. Compositions provided herein include (i) a polypeptide including a signal-regulatory protein ? (SIRP-?) D1 variant and (ii) an antibody.

Abstract: Provided herein, inter alia, are isolated antibodies that bind an extracellular domain of a human SIRP-? v1 polypeptide (e.g., the D1 domain), an extracellular domain of a human SIRP-? v2 polypeptide or both. In some embodiments, the antibodies also bind an extracellular domain of a monkey SIRP-? polypeptide, an extracellular domain of a SIRP-? polypeptide, an extracellular domain of a human SIRP-? polypeptide, and/or an extracellular domain of a human SIRP-? polypeptide. In some embodiments, the antibodies block or do not binding between an extracellular domain of a human SIRP-? polypeptide and an IgSF domain of a human CD47 polypeptide, while in some embodiments, the antibodies reduce the affinity of a human SIRP-? polypeptide for binding an IgSF domain of a human CD47 polypeptide. Further provided herein are methods, polynucleotides, vectors, and host cells related thereto.

Abstract: A parking brake system is disclosed and includes a parking brake valve configured to maintain a fluid pressure of the parking brake system and one or more pressure transducers that monitor the fluid pressure of the parking brake system. The parking brake system also includes a bistable control valve fluidly connected to the parking brake valve, one or more processors in electronic communication with the bistable control valve, the parking brake valve, and the one or more pressure transducers, and a memory coupled to the one or more processors. The memory stores data comprising a database and program code that, when executed by the one or more processors, causes the parking brake system to instruct the bistable control valve to actuate into the opened position when the fluid pressure of the parking brake system is less than a threshold pressure.

Abstract: Brake control systems are disclosed herein. A brake control system comprises a first set of analog-to-digital converters in electrical communication with a first set of brake input mechanism sensors and a second set of analog-to-digital converters in electrical communication with a second set of brake input mechanism sensors. The first and second sets of analog-to-digital converters comprise one or more of different hardware and different software for differentially manipulating sensor outputs received from the brake input mechanism sensors.

Abstract: A brake system is disclosed. The brake system includes a brake stack having a stack closure pressure, a force member positioned within a cylinder, a valve configured to control the fluid pressure of the brake system, and one or more pressure transducers that generate a proportional electrical signal representative of fluid pressure within the cylinder. The brake system also includes one or more processors in electronic communication with the valve, the one or more pressure transducers, and a memory coupled to the one or more processors. The memory stores data comprising a database and program code that, when executed by the one or more processors, causes the brake system to determine the stack closure pressure of the brake stack.

Abstract: The present disclosure features signal-regulatory protein ? (SIRP-?) polypeptides and constructs that are useful, e.g., to target a cell (e.g., a cancer cell or a cell of the immune system), to increase phagocytosis of the target cell, to eliminate immune cells such as regulatory T-cells, to kill cancer cells, to treat a disease (e.g., cancer) in a subject, or any combinations thereof. The SIRP-? constructs include a high affinity SIRP-? D1 domain or variant thereof that binds CD47 with higher affinity than a wild-type SIRP-?. The SIRP-? polypeptides or constructs include a SIRP-? D1 variant fused to an Fc domain monomer, a human serum albumin (HSA), an albumin-binding peptide, or a polyethylene glycol (PEG) polymer. Compositions provided herein include (i) a polypeptide including a signal-regulatory protein ? (SIRP-?) D1 variant and (ii) an antibody.

Abstract: A parking brake system is disclosed and includes a parking brake valve configured to maintain a fluid pressure of the parking brake system and one or more pressure transducers that monitor the fluid pressure of the parking brake system. The parking brake system also includes a bistable control valve fluidly connected to the parking brake valve, one or more processors in electronic communication with the bistable control valve, the parking brake valve, and the one or more pressure transducers, and a memory coupled to the one or more processors. The memory stores data comprising a database and program code that, when executed by the one or more processors, causes the parking brake system to instruct the bistable control valve to actuate into the opened position when the fluid pressure of the parking brake system is less than a threshold pressure.