Abstract: An example includes a device having a base platform, a seat platform, and a swivel joint. The base platform is configured for affixation to an occupant seat of a motor vehicle. The base platform has a first and second base retainer component. The seat platform has a seat portion and a back portion. The seat platform has a first and a second seat retainer complement. The swivel joint couples the base platform and the seat platform and permits relative motion of the base platform and the seat platform about a rotary axis and constrain motion on other axes. At a first position of the base platform relative to the seat platform, the first seat retainer complement aligns with the first base retainer component. At a second position of the base platform relative to the seat platform (second position different than the first position), the second seat retainer complement aligns with the second base retainer component.

Abstract: The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using the compositions as a COVID-19 vaccine for the treatment of a coronavirus infection are also provided.

Abstract: Provided herein are dried compositions and methods for preparing such compositions for use in delivery of a nucleic acid to a subject. The dried composition may comprise a lipid carrier, wherein the lipid carrier is a nanoemulsion comprising a hydrophobic core, optionally one or more inorganic nanoparticles and one or more lipids, one or more nucleic acid, and at least one cryoprotectant. Methods of using these dried compositions for treatment are also provided.

Abstract: Techniques for facilitating an autonomous operation, such as an autonomous navigation, of an unmanned vehicle based on one or more fiducials. For example, image data of a fiducial may be generated with an optical sensor of the unmanned vehicle. The image data may be analyzed to determine a location of the fiducial. A location of the unmanned vehicle may be estimated from the location of the fiducial and the image. The autonomous navigation of the unmanned vehicle may be directed based on the estimated location.

Abstract: The invention relates to a compound of formula (I) wherein A1, R1, R2, R3, R4 and R5 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament for treatment of indications associated with Salt-inducible kinases (SIK) such as of rheumatoid arthritis, juvenile rheumatoid arthritis, non-alcoholic steatohepatitis (NASH), primary sclerosing cholangitis, giant cell vasculitis, inflammatory bowel diseases (IBD), atherosclerosis, type 2 diabetes or glomerulonephritis.

Abstract: The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using these compositions as a vaccine for treatment of an infectious disease are also provided.

Abstract: The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using the compositions as a COVID-19 vaccine for the treatment of a coronavirus infection are also provided.

Abstract: The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Compositions described herein include lipid carriers, optionally including an inorganic particle, capable of admixing with nucleic acids. Nucleic acids provided herein include those encoding for cancer antigens (full length proteins or fragments) as well as antibodies. Methods of using the compositions as a therapeutic vaccine for the treatment of a cancer are also provided.

Abstract: Provided herein are dried compositions and methods for preparing such compositions for use in delivery of a nucleic acid to a subject. The dried composition may comprise a lipid carrier, wherein the lipid carrier is a nanoemulsion comprising a hydrophobic core, optionally one or more inorganic nanoparticles and one or more lipids, one or more nucleic acid, and at least one cryoprotectant. Methods of using these dried compositions for treatment are also provided.

Abstract: A shower seat assembly comprising a first mounting bracket with a front side and a back side, a second mounting bracket with a front side and a back side, a first support rod hingedly connected to the first mounting bracket, a first tube stop secured to the first mounting bracket, a second support rod hingedly connected to the second mounting bracket, a second tube stop secured to the second mounting bracket, a first spring operationally associated with the first mounting bracket and the first support rod, a second spring operationally associated with the second mounting bracket and the second support rod, and a seat with an upper surface and a lower surface secured by its lower surface to the first support rod and the second support rod; wherein the back side of the first mounting bracket and second mounting bracket are each engaged to a vertical or near vertical surface.

Abstract: Disclose is a separator for separating liquid from a fluid stream including a mixture of gas and liquid. The separator comprises a first vessel including an outlet and an inlet for receiving the fluid stream, the first vessel in fluid communication with a second vessel via a first valve, the second vessel in fluid communication with a liquid outlet via a second valve, wherein the first vessel is arranged to enable the liquid to flow into the second vessel. The separator also has a second valve for controlling release of liquid from the second vessel, the first and second valves being pneumatically operated, the pneumatic operation of the first and second valves allowing only one of the first and second valves to be open during operation of the separator.

Abstract: Techniques for facilitating an autonomous operation, such as an autonomous navigation, of an unmanned vehicle based on one or more fiducials. For example, image data of a fiducial may be generated with an optical sensor of the unmanned vehicle. The image data may be analyzed to determine a location of the fiducial. A location of the unmanned vehicle may be estimated from the location of the fiducial and the image. The autonomous navigation of the unmanned vehicle may be directed based on the estimated location.

Abstract: A system for measuring temperature in an electric motor, including a stator with field windings in the electric motor and a circuit board proximate to the field windings. The system further includes one or more thermo-electric temperature responsive devices. The thermo-electric temperature devices are mountable onto a surface of the circuit board facing the field windings. The system further includes a thermally conductive, but non-electrically conductive material, connecting the one or more thermo-electric devices to the stator windings.

Abstract: Disclosed are methods and systems for delivery of items using an unmanned aerial vehicle (“UAV”). A user may be provided with a delivery location identifier (“DLI”) that is to be placed at a delivery location within a delivery destination to identify where a UAV is to position an item as part of a delivery to the delivery destination. For example, the delivery destination may be a user's home. Within the deliver destination of the user's home, the user may select a delivery location, such as a spot in the back yard wherein the UAV is to position the ordered item as part of the delivery. To aid the UAV in navigating to the delivery location, the user places the DLI at the delivery location. The UAV detects the DLI and positions the item at or near the DLI as part of the item delivery.

Abstract: Systems and methods for providing a multi-direction wind tunnel, or “windball,” are disclosed. The system can have a series of fans configured to provide air flow in a plurality of directions to enable accurate testing of aircraft, unmanned aerial vehicles (UAVs), and other vehicles capable of multi-dimensional flight. The system can comprise a spherical or polyhedral test chamber with a plurality of fans. The fans can be arranged in pairs, such that a first fan comprises an intake fan and a second fan comprises an exhaust fan. The direction of the air flow can be controlled by activating one or more pairs of fans, each pair of fan creating a portion of the air flow in a particular direction. The direction of the air flow can also be controlled by rotating one or more pairs of fans with respect to the test chamber on a gimbal device, or similar.

Abstract: A monitoring and messaging system for monitoring status of a plurality of assets. The system includes a data collection and normalization module configured to accept data originating from a plurality of sensors and to convert the data to normalized data for subsequent processing by the system. The system has an identification module configured to receive the normalized data and assign a subset of the normalized data generated by one or more specific sensors of the plurality of sensors to an asset selected from a plurality of assets. The system has an analysis module which includes a database of asset rules defining status states of the asset. The analysis module is programmed to receive and compare the subset of normalized data with a subset of asset rules to determine a status state of the asset. The system also has an action module which is configured to receive the status state of the asset, generate a message representing the status state of the asset and to transmit the message to a concerned party.

Abstract: A continuous belt screen assembly and system used for filtering fluid for various municipal and industrial purposes. The assembly includes a pair of spaced, endless belts, lifters, and screen panels. Each lifter is operably mounted to the pair of belts for lifting of solid waste out of the fluid in the channel. Each of the screen panels can be interposed between lifters and secured in place by opposing slots defined by the lifters. The endless belts can include toothed drive links, with the ends of the teeth extending with the ends of the drive links to define an involute profile. The lifters can include a sleeve portion for receiving a pivot shaft and a paddle portion extending from the sleeve portion, terminating at a free end that can be contoured to have teeth. The lifters can be a flexible material configured to deflect.

Abstract: A small, rugged, concentric square, forward-pivot, assembly with motorized pan and tilt, two-point suspension of pan and tilt axes, multiple photo-sensors, and capable of using lenses that are much larger than pinhole lenses, is provided. It is combined with a motorized zoom lens, image sensor, processor and enclosure to form a covert outdoor video surveillance camera. It enables a viewing window for the lens to be small yet provide large angles of view without needing a light-losing, dark material or sharpness-losing perforated media to conceal it, and captures much more light than a pinhole. Three photo sensors are arranged around the lens and collectively control an IR-cut filter. The sensors are integrated into the assembly to point in the same direction as the lens, and provide a good assessment of the scene brightness even when some of them have been panned or tilted out of view of the window.

Abstract: Techniques for facilitating an autonomous operation, such as an autonomous navigation, of an unmanned vehicle based on one or more fiducials. For example, image data of a fiducial may be generated with an optical sensor of the unmanned vehicle. The image data may be analyzed to determine a location of the fiducial. A location of the unmanned vehicle may be estimated from the location of the fiducial and the image. The autonomous navigation of the unmanned vehicle may be directed based on the estimated location.

Abstract: Decoder techniques in accordance with embodiment of the present technology include partially decoding a compressed file on a serial based processing unit to find offsets of each of a plurality of entropy data blocks. The compressed file and offset for each of the plurality of entropy encoded data blocks are transferred to a parallel based processing unit. Thereafter, the compressed file is at least partially decoded on the parallel based processing unit using the offset for each of the plurality of entropy encoded data blocks.