Patents by Inventor Steven H. Spergel

Steven H. Spergel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-imidazo[4,5-]thieno[3,2-]pyridine based tricyclic compounds and pharmaceutical compositions comprising same
    Patent number: 7683171
    Abstract: The present invention provides for thiazolopyridine-based tricyclic compounds having the formula (I), wherein R1, R2, R5, R6 and R7 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.
    Type: Grant
    Filed: February 3, 2006
    Date of Patent: March 23, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: William J. Pitts, Jagabandhu Das, Yuping Qiu, Steven H. Spergel
  • Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
    Patent number: 7655689
    Abstract: Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: February 2, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Mark E. Salvati, James Aaron Balog, Dacia A. Pickering, Sören Giese, Aberra Fura, Wenying Li, Ramesh N. Patel, Ronald L. Hanson, Toomas Mitt, Jacques Y. Roberge, James R. Corte, Steven H. Spergel, Richard A. Rampulla, Raj N. Misra, Hai-Yun Xiao
  • 8H-imidazo[4,5-D]thiazolo[4,5-B]pyridine based tricyclic compounds and pharmaceutical compositions comprising same
    Patent number: 7557211
    Abstract: The present invention provides for thiazolopyridine-based tricyclic compounds having the formula (I), wherein R1, R2, R5 and R6 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: July 7, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jagabandhu Das, James Kempson, William J. Pitts, Steven H. Spergel
  • Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
    Patent number: 7517904
    Abstract: Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: April 14, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Mark E. Salvati, James Aaron Balog, Dacia A. Pickering, Sören Giese, Aberra Fura, Wenying Li, Ramesh N. Patel, Ronald L. Hanson, Toomas Mitt, Jacques Y. Roberge, James R. Corte, Steven H. Spergel, Richard A. Rampulla, Raj N. Misra, Hai-Yun Xiao
  • Imidazo-fused oxazolo [4,5-]pyridine and imidazo-fused thiazolo[4,5-]pyridine based tricyclic compounds and pharmaceutical compositions comprising same
    Patent number: 7456194
    Abstract: The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I), wherein R1, R2, R3, and R6 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: November 25, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Alaric Dyckman, William J. Pitts, Makonen Belema, Patrice Gill, James Kempson, Yuping Qiu, Claude Quesnelle, Steven H. Spergel, F. Christopher Zusi
  • Thiazolyl inhibitors of Tec family tyrosine kinases
    Patent number: 7241781
    Abstract: Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: July 10, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joel C. Barrish, Jagabandhu Das, Steven B. Kanner, Chunjian Liu, Steven H. Spergel, John Wityak, Arthur M. P. Doweyko, Joseph A. Furch, III
  • Imidazo-fused oxazolo[4,5-?]pyridine and imidazo-fused thiazolo[4,5-?]pyridine based tricyclic compounds and pharmaceutical compositions comprising same
    Patent number: 7176214
    Abstract: The present invention provides for pyrazolopurine-based tricyclic compounds having the formula (I), wherein R1, R2, R3, R4, R5 and R6 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: February 13, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: William J. Pitts, Makonen Belema, Patrice Gill, James Kempson, Yuping Qiu, Claude A. Quesnelle, Steven H. Spergel, Fred Christopher Zusi
  • Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
    Patent number: 7141578
    Abstract: Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: October 25, 2004
    Date of Patent: November 28, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Mark E. Salvati, James Aaron Balog, Dacia A. Pickering, Sören Giese, Aberra Fura, Wenying Li, Ramesh N. Patel, Ronald L. Hanson, Toomas Mitt, Jacques Y. Roberge, James R. Corte, Steven H. Spergel, Richard A. Rampulla, Raj N. Misra, Hai-Yun Xiao
  • Thiazolyl inhibitors of Tec family tyrosine kinases
    Patent number: 7037926
    Abstract: Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
    Type: Grant
    Filed: August 15, 2003
    Date of Patent: May 2, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joel C. Barrish, Jagabandhu Das, Steven B. Kanner, Chunjian Liu, Steven H. Spergel, John Wityak, Arthur M. P. Doweyko, Joseph A. Furch, III
  • Thiazolyl inhibitors of Tec family tyrosine kinases
    Patent number: 6958336
    Abstract: Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
    Type: Grant
    Filed: August 15, 2003
    Date of Patent: October 25, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joel C. Barrish, Jagabandhu Das, Steven B. Kanner, Chunjian Liu, Steven H. Spergel, John Wityak, Arthur M. P. Doweyko, Joseph A. Furch, III
  • Thiazolyl inhibitors of Tec family tyrosine kinases
    Patent number: 6956045
    Abstract: Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
    Type: Grant
    Filed: August 15, 2003
    Date of Patent: October 18, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joel C. Barrish, Jagabandhu Das, Steven B. Kanner, Chunjian Liu, Steven H. Spergel, John Wityak, Arthur M. P. Doweyko, Joseph A. Furch, III
  • Thiazolyl inhibitors of Tec family tyrosine kinases
    Patent number: 6953795
    Abstract: Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
    Type: Grant
    Filed: August 15, 2003
    Date of Patent: October 11, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joel C. Barrish, Jagabandhu Das, Steven B. Kanner, Chunjian Liu, Steven H. Spergel, John Wityak, Arthur M. P. Doweyko, Joseph A. Furch III
  • Thiazolyl inhibitors of Tec family tyrosine kinases
    Publication number: 20040110752
    Abstract: Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
    Type: Application
    Filed: August 15, 2003
    Publication date: June 10, 2004
    Inventors: Joel C. Barrish, Jagabandhu Das, Steven B. Kanner, Chunjian Liu, Steven H. Spergel, John Wityak, Arthur M.P. Doweyko, Joseph A. Furch
  • Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
    Publication number: 20040077605
    Abstract: Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: December 18, 2002
    Publication date: April 22, 2004
    Inventors: Mark E. Salvati, James Aaron Balog, Dacia A. Pickering, Soren Giese, Aberra Fura, Wenying Li, Ramesh N. Patel, Ronald L. Hanson, Toomas Mitt, Jacques Y. Roberge, James R. Corte, Steven H. Spergel, Richard A. Rampulla, Raj N. Misra, Hai-Yun Xiao
  • Thiazolyl inhibitors of Tec family tyrosine kinases
    Publication number: 20040077695
    Abstract: Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
    Type: Application
    Filed: August 15, 2003
    Publication date: April 22, 2004
    Inventors: Jo I C. Barrish, Jagabandhu Das, Steven B. Kanner, Chunjian Liu, Steven H. Spergel, John Wityak, Arthur M. P. Doweyko, Joseph A. Furch
  • Thiazolyl inhibitors of Tec family tyrosine kinases
    Publication number: 20040067989
    Abstract: Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
    Type: Application
    Filed: August 15, 2003
    Publication date: April 8, 2004
    Inventors: Joel C. Barrish, Jagabandhu Das, Steven B. Kanner, Chunjian Liu, Steven H. Spergel, John Wityak, Arthur M. P. Doweyko, Joseph A. Furch
  • Thiazolyl inhibitors of Tec family tyrosine kinases
    Publication number: 20040067990
    Abstract: Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
    Type: Application
    Filed: August 15, 2003
    Publication date: April 8, 2004
    Inventors: Joel C. Barrish, Jagabandhu Das, Steven B. Kanner, Chunjian Liu, Steven H. Spergel, John Wityak, Arthur M. P. Doweyko, Joseph A. Furch
  • Thiazolyl inhibitors of Tec family tyrosine kinases
    Patent number: 6706717
    Abstract: Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: March 16, 2004
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joel C. Barrish, Jagabandhu Das, Steven B. Kanner, Chunjian Liu, Steven H. Spergel, John Wityak, Arthur M. P. Doweyko, Joseph A. Furch, III
  • Imidazoquinoxaline protein tyrosine kinase inhibitors
    Patent number: 6635626
    Abstract: Novel imidazoquinoxalines and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic disorders.
    Type: Grant
    Filed: June 15, 1998
    Date of Patent: October 21, 2003
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Joel C. Barrish, Steven H. Spergel
  • Thiazolyl inhibitors of Tec family tyrosine kinases
    Publication number: 20030069238
    Abstract: Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
    Type: Application
    Filed: December 20, 2001
    Publication date: April 10, 2003
    Inventors: Joel C. Barrish, Jagabandhu Das, Steven B. Kanner, Chunjian Liu, Steven H. Spergel, John Wityak, Arthur M. P. Doweyko, Joseph A. Furch