Abstract: A method comprises depositing a barrier layer on a dielectric layer to prevent oxidation of a metal layer to be deposited by electroplating due to an oxide present in the dielectric layer and depositing a doped liner layer on the barrier layer to bond with the metal layer to be deposited on the liner layer by the electroplating. The dopant forms a protective passivation layer on a surface of the liner layer and dissolves during the electroplating so that the metal layer deposited on the liner layer by the electroplating bonds with the liner layer. The dopant reacts with the dielectric layer and forms a layer of a compound between the barrier layer and the dielectric layer. The compound layer prevents oxidation of the barrier layer and the liner layer due to the oxide present in the dielectric layer and adheres the barrier layer to the dielectric layer.

Abstract: Examples are disclosed that relate to dynamically controlling light sources on an optically trackable peripheral device. One disclosed example provides a near-eye display device comprising an image sensor, a communications subsystem, a logic subsystem, and a storage subsystem. The storage subsystem stores instructions executable by the logic subsystem to control a peripheral device comprising a plurality of light sources by receiving image data from the image sensor, identifying in the image data a constellation of light sources formed by a subset of light sources of the peripheral device, and based upon the constellation of light sources identified, send to the peripheral device via the communications subsystem constellation information related to the constellation of light sources identified.

Abstract: The present invention relates to polypeptide modulators of complement activity, including cyclic polypeptide modulators. Included are methods of utilizing such modulators as therapeutics.

Abstract: A bioreactor system and packaging is provided. The bioreactor system includes a vessel for housing biomaterials for processing and a support structure. The vessel includes a flexible material defining a chamber and a mixing system positioned within the chamber. The mixing system includes an agitator for imparting motion and mixing to the contents of the vessel and includes a base affixed to the flexible material at a base section of the chamber, a shaft moveably mounted in the base and extending from the base into the chamber and at least one mixing element mounted to the shaft, the shaft configured to be driven by a motor magnetically coupled to the shaft and external to the lower portion of the chamber. The support structure is connected to the mixing system such that the shaft is moveable therein and configured to cooperate with an external structure to provide support for the shaft.

Abstract: A system for performing industrial automation control may include an audio device that receives audio data from an element in an industrial automation system. The audio device may determine orientation data based on the audio data. In addition, the audio device may determine an automation command to control a machine in the industrial automation system based on the audio data and the orientation data. After determining the automation command, the audio device may implement a first control action for the machine based at least in part on the automation command, where the first control action causes the machine to adjust an operation.

Abstract: A system for performing industrial automation control may include an audio device that receives audio data from an element in an industrial automation system. The audio device may determine orientation data based on the audio data. In addition, the audio device may determine an automation command to control a machine in the industrial automation system based on the audio data and the orientation data. After determining the automation command, the audio device may implement a first control action for the machine based at least in part on the automation command, where the first control action causes the machine to adjust an operation.

Abstract: A water filtration device comprising a drum housing a removable canister containing a replaceable water filter media. A pair of lifting handle/media stops, connected to the removable canister, pivotally secure the replaceable water filter media, enabling a user to lift the removable canister from the drum and remove the replaceable water filter media. The drum is located along and connected to a water circulating line comprising a water supply line and a water discharge line. Unfiltered water is circulated into the water filtration device, creating the filtered water circulating into the water discharge line to the decorative water feature thereby re-circulating the unfiltered water from the water filtration device as filtered water back through a decorative water feature to a water feature terminus. As unfiltered water is pumped from the water feature terminus, it again passes through the replaceable water filter media.

Abstract: The present invention relates to a drug delivery system and uses thereof. Specifically, a system that can be used to deliver therapeutic proteins, including antibodies, to proteolytic environments is disclosed. In one form of the invention the drug delivery system is a composition which comprises a porous substrate and an antibody bound to the substrate. In one embodiment, the composition comprises nanoporous silicon and can be used to deliver antibodies for the treatment, or for improving the repair, of a wound.

Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

Abstract: Examples are disclosed that relate to dynamically controlling light sources on an optically trackable peripheral device. One disclosed example provides a near-eye display device comprising an image sensor, a communications subsystem, a logic subsystem, and a storage subsystem. The storage subsystem stores instructions executable by the logic subsystem to control a peripheral device comprising a plurality of light sources by receiving image data from the image sensor, identifying in the image data a constellation of light sources formed by a subset of light sources of the peripheral device, and based upon the constellation of light sources identified, send to the peripheral device via the communications subsystem constellation information related to the constellation of light sources identified.

Abstract: A surface cleaning apparatus is described including a floor head, a housing supporting a suction source and a dirt collection container having an elongate axis (A). The device further includes an elongate member having an elongate axis (B), said elongate member connecting the floor head to the housing, said elongate member including a passage for carrying dirt-laden air from the floor head to the dirt collection container. The elongate axis (B) of the elongate member intersects or substantially intersects the elongate axis (A) of the dirt collection container.

Abstract: A surgical robot comprising a surgical robot arm and a surgical instrument. The surgical robot arm terminates at its distal end in a drive assembly comprising a first drive interface element. The surgical instrument comprises a shaft, an articulation attached to the distal end of the shaft, and a driving mechanism at the proximal end of the shaft. The articulation is for articulating an end effector, the articulation driveable by at least a first driving element and a second driving element. The driving mechanism comprises a first instrument interface element to which the first driving element is connected and a second instrument interface element to which the second driving element is connected.

Abstract: A robot comprising an arm extending between a base and an attachment for an end effector, the arm comprising: a first arm part; a second arm part distal of the first arm part; and a joint whereby the first and second arm parts are coupled together, the joint permitting the first and second arm parts to rotate relative to each other about at least two mutually offset axes; a control rod attached to the second part of the arm at a location spaced from the first and second axes, the control rod extending distally of that location along the first arm part; and a drive mechanism for driving the control rod to move relative to the first arm part and thereby alter the attitude of the second arm part relative to the first arm part.

Abstract: Unmanned aerial vehicles (UAVs) may be configured and deployed to maintain inventory and retrieve products for delivery. The UAVs can be equipped with a plurality of sensors used to assess the condition of inventory items, report the condition to a central control, and to retrieve inventory items. The UAVs can scan fruits and vegetables, for example, to determine the current ripeness. The UAV can then harvest the items if ready or provide a status update if they are not ready. The UAVs can be used in conjunction with transporters and harvesters to deliver products from the field or warehouse to a central control or directly to the customer. In scanning the products for readiness, the UAVs can also detect issues such as spoilage, fungus, and pests. This information can be used for the specific application of treatments.

Abstract: A system and method are provided for training a machine learning system. In an embodiment, the system generates a three-dimensional model of an environment using a video sequence that includes individual frames taken from a variety of perspectives and environmental conditions. An object in the environment is identified and labeled, in some examples, by an operator, and a three-dimensional model of the object is created. Training data for the machine learning system is created by applying the label to the individual video frames of the video sequence, or by applying a rendering of the three-dimensional model to additional images or video sequences.

Abstract: The invention provides BTK Inhibitor compounds, pharmaceutically acceptable salts, pharmaceutical compositions thereof, and methods of using these compounds, salts, or compositions to treat autoimmune diseases such as Rheumatoid Arthritis.

Abstract: A robot comprising: a base; a flexible arm extending from the base and having: a plurality of joints whereby the configuration of the arm can be altered, a plurality of drivers arranged to drive the joints to move, and an attachment structure for attaching a tool to the arm; and a control unit configured to control the drivers and to receive inputs from sensors, and operable in a mode in which, whilst a tool is attached to the attachment structure and captive in a port, it: (i) controls the drivers to permit the arm to be reconfigured by the action of an external force applied to the arm so as to cause the tool to be retracted from the port along a longitudinal axis of the tool; and (ii) on receiving sensor input indicating that the arm has been reconfigured so as to cause the tool to be retracted from the port along a longitudinal axis of the tool, controls the drivers to reconfigure the arm so as to agitate the tool transverse to the longitudinal axis of the tool.

Abstract: A system for securely depositing an item includes: a deposit box with a door configured to provide selective access to an interior space in the deposit box; a lock mechanism configured to attach to the deposit box to selectively block the door from opening; a first proximity sensor operatively connected to the lock mechanism to operate the lock mechanism to block the door or allow the door to open; a second proximity sensor configured to be attached to at least one of: a delivery person and a piece of delivery equipment; a third proximity sensor; and a first transmitter operatively connected to the lock mechanism and configured to transmit a signal indicative of operating information regarding the lock mechanism, and wherein the deposit box is at least 18 inches wide and 24 inches long.

Abstract: A system for symbolic communication including a communication system, a sender communication device including a processor and a memory, a symbolic communication software module stored in the sender communication device memory, the symbolic communication software module including a database of symbols, with some of the symbols being billable, each billable symbol being associated with a merchant and having a billing rate associated with its use in a message, the symbolic communication software module comprising executable instructions that when executed by the processor cause the processor to allow a user to select symbols to compose a message; send the message to a receiver communication device using a communication system; count and record each symbols used in the message in the symbol server, and bill the merchant for the use of the billable symbol in a message, using the billing rate associated with the billable symbol.

Abstract: A submerged combustion melting system (90) includes a submerged combustion melter (100) having a housing with one or more side walls (104), a floor (106), and a ceiling (108) which at least partially define a melt chamber (110). The melter has one or more main burners (128) positioned along the floor of the housing and an oxygen/gas burner in a preheat burner system (300) removably attached to one of the sidewalls or the ceiling, the oxygen/gas burner arranged such that a flame from the oxygen/gas burner is directed downward into the melt chamber.