Abstract: Direct access to host memory for guests is disclosed. For example, a system includes a processor, a host memory, a filesystem daemon, a guest including a storage controller, and a filesystem queue accessible to the filesystem daemon and the storage controller. The storage controller receives a file retrieval request associated with a file stored in the host memory and forwards the file retrieval request to the filesystem daemon by adding the file retrieval request to the filesystem queue. The filesystem daemon retrieves the file retrieval request from the filesystem queue, determines a host memory address (HMA) associated with the file, and causes the HMA to be mapped to a guest memory address (GMA). The guest accesses the file in the host memory with the GMA, and later terminates access to the file, where the filesystem daemon is then configured cause the GMA to be unmapped.

Abstract: Ceramic honeycomb extrusion apparatus and a method of extruding a honeycomb body are disclosed. The honeycomb extrusion apparatus and method utilize a homogenizer plate comprising through holes and a screen support plate comprising screen support plate openings and aligned with the through holes.

Abstract: Secure and efficient access to host memory for guests is disclosed. For example, a system includes (i) a processor, (ii) a host memory, (iii) a hypervisor including a filesystem daemon, (iv) a guest including a storage controller, and (v) a first filesystem queue. The storage controller is configured to receive a file request, translate the file request, and add the translated file request to a filesystem queue. The filesystem daemon is configured to retrieve the translated file request from the filesystem queue and provide access to a file in the host memory identified in the file request to the guest.

Abstract: A Distributed Availability Group (DAG) spans two AGs, each spanning one or more replica nodes and functioning as primary or secondary AG. A primary AG is replicated to the secondary AG synchronously or asynchronously. A failover in the DAG results in the AGs swapping their roles. Multiple DAGs can be linked together as a chain, which provides many useful features including disaster recovery across geographical regions, massive read scale (numerous readable secondary nodes), online migration of databases (across different operating systems and computing environments). The systems using DAGs can replicate databases across multiple independent high availability (HA) failover clusters using complex replication topologies and allow for manual failover and failback. The systems allow chaining of multiple AGs to provision a treelike structure of replicas and numerous secondary replicas without impacting performance.

Abstract: A data processing system includes a host processor that executes an operating system and an accelerator operable to process data under the control of the operating system executing on the host processor. The accelerator can be switched between a normal mode of operation and a protected mode of operation in which the side channel information that can be provided by the accelerator to the host processor is restricted. The data processing system also includes a mechanism for switching the accelerator from its normal mode of operation to the protected mode of operation, and from its protected mode of operation to the normal mode of operation.

Abstract: Disclosed herein are polynucleotide agents (including interfering RNA agents (RNAi)), small molecule agents, and synthetic cells, methods of making the same, and their use as therapeutics against age-related dysfunction and/or cellular dysfunction that results in various disease states. In some embodiments, one or more agents as disclosed herein can be used to target and/or decrease the expression of the paired-box protein 5 (PAX5) gene, protein phosphatase, Mg2+/Mn2+ dependent 1F (PPM1F) gene, or both. Also disclosed herein are methods for the preparation and use of synthetic cells prepared by in vitro and/or in vivo manipulation using one or more cellular factors, polynucleotide agents, and/or small molecule agents. Disclosed herein is the use of these cells as therapeutic cells that treat age-related dysfunction and/or cellular dysfunction resulting in various disease states.

Abstract: Methods and apparatus to determine media impressions using distributed demographic information are disclosed.

Abstract: A system has a pre-recorded content database. Further, the system has a processor that establishes a virtual scratch card game, randomly determines a plurality of positions in a virtual scratch card grid that correspond to a winning outcome of the virtual scratch card game, searches for a plurality of pre-recorded video clips in the pre-recorded content database such that each of the plurality of pre-recorded video clips displays an event corresponding to the winning outcome, and provides the plurality of pre-recorded video clips to a display device that renders the virtual scratch card grid according to a plurality of scratch-off blocks that, when activated, reveal each of the plurality of pre-recorded video clips at each of the corresponding plurality of positions.

Abstract: A system has a pre-recorded content database. Further, the system has a processor that generates a graphical user interface that renders a virtual scratch card game. The processor receives a participant user input corresponding to one of the plurality of selection indicia. Further, the processor randomly determines a plurality of events in a plurality of pre-recorded video clips. The processor also associates a game image with each of the plurality of pre-recorded video clips in the interactive menu such that a rendering device renders a corresponding pre-recorded video clip from the plurality of pre-recorded video clips based on game imagery user input. The graphical user interface comprises a plurality of selection indicia associated with less than a totality of potential virtual sport-based game participants. Further, the graphical user interface comprises an interactive menu of game imagery.

Abstract: The disclosed computer-implemented method may include receiving, from devices in an environment, real-time data associated with the environment and determining, from the real-time data, current object data for the environment. The current object data may include both state data and relationship data for objects in the environment. The method may also include determining object deltas between the current object data and prior object data from an event graph. The prior object data may include prior state data and prior relationship data for the objects. The method may include detecting an unknown state for one of the objects, inferring a state for the object based on the event graph, and updating the event graph based on the object deltas and the inferred state. The method may further include sending updated event graph data to the devices. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The present invention relates to the treatment of or alleviation of signs and symptoms of palmoplantar pustulosis (PPP) with anti-IL-36R antibodies in a patient.

Abstract: A method for determining a rate at which solid particles settle from a liquid in a slurry includes (a) mixing the solid particles and the liquid to form the slurry. In addition, the method includes (b) placing the slurry in an inner cavity of a vessel. Further, the method includes (c) measuring a hydrostatic pressure of the slurry at a bottom of the inner cavity over a period of time after (b). The method also includes (d) determining a quantity of the solid particles that settle from the liquid as a function of time over the period of time using the hydrostatic pressure measurements from (c).

Abstract: Disclosed herein are active agents, compositions containing them, unit dosage forms containing them, and methods of their use, e.g., for treating a metabolic disorder or nonalcoholic fatty liver disease or for modulating a metabolic marker or nonalcoholic fatty liver disease marker.

Abstract: Disclosed herein are acylated active agents and methods of their use, e.g., for modulating an autoimmunity marker or for treating an autoimmune disorder.

Abstract: The present invention is directed towards a beverage dispensing apparatus comprising at least one beverage dispensing module and a base unit upon or within which the or each module is positioned. Each module comprises a container housing a beverage reservoir and a beverage dispensing arrangement comprising a dispensing valve operable to be selectively opened to dispense beverage from the reservoir. Each module further comprises valve sensing means operable to determine when the dispensing valve is opened and provide a valve status signal indicative of whether the dispensing valve is opened. Each module further comprises communication means in communication with the valve sensing means and arranged to receive the valve status signal. The base unit comprises a base-module receiver operable to communicate with the communication means of one or more modules to receive the valve status signal therefrom. The apparatus is particularly suitable for alcoholic beverages.

Abstract: A depth measurement assembly (DMA) includes a structured light emitter, an augmented camera, and a controller. The structured light emitter projects structured light into a local area under instructions from the controller. The augmented camera generates image data of an object illuminated with the structured light pattern projected by the structured light emitter in accordance with camera instructions generated by the controller. The augmented camera includes a high speed computation tracking sensor that comprises a plurality of augmented photodetectors. Each augmented photodetector converts light to data and stores the data in its own memory unit. The controller receives the image data and determines depth information of the object in the local area based in part on the image data. The depth measurement unit can be incorporated into a head-mounted display (HMD).

Abstract: A patient interface for delivering breathable gas to a patient includes a nasal prong assembly including a pair of nasal prongs structured to sealingly communicate with nasal passages of a patient's nose in use and headgear to maintain the nasal prong assembly in a desired position on the patient's face. The headgear includes side straps and rigidizers provided to respective side straps. Each rigidizer includes a first end portion that provides a connector structured to engage a respective end of the nasal prong assembly and an inwardly curved protrusion in the form of a cheek support that curves inwardly of the connector. The cheek support is adapted to follow the contour of the patient's cheek and guide a respective end portion of the side strap into engagement with the patient's cheek to provide a stable cheek support.

Abstract: Orally-administrable, pharmaceutical formulations comprising a plurality of pellets are described herein. The pellets comprise a core, a release coating, and an enteric coating, where the release coating comprises, for example, an HPMC.

Abstract: Methods and systems for synopsizing videos of an incident from multiple moving video cameras. One system includes an electronic processor configured to receive a first video from a first moving video camera, receive a second video from a second moving video camera, determine a first motion characteristic of the first video, and determine a second motion characteristic of the second video. The electronic processor is further configured to generate a comparison between the first motion characteristic and the second motion characteristic, modify the second video based on the comparison such that the second motion characteristic aligns with the first motion characteristic, and generate, after modifying the second video, a combined video including at least a portion of both the first video and the second video.