Abstract: This invention generally relates to methods for the treatment of IL-23 related diseases, in particular inflammatory diseases, such as psoriasis or psoriatic arthritis, utilizing anti-IL-23A antibodies.

Abstract: A utility meter includes a meter housing that supports at least one current coil, a temperature sensor, and a processing circuit coupled to both. The current coil can be coupled to receive heat energy from a meter socket. The temperature sensor disposed generates a sensor signal based on a temperature within the meter housing. The processing circuit obtains the sensor signal and generates meter temperature information based at least in part thereon. The processing circuit also obtains a first predetermined threshold based on at least one of time of day information and date information. The processing circuit also determines whether an abnormal condition exists by comparing the meter temperature information to a value based on the first predetermined threshold, and generates an output signal to a memory, display or communication circuit responsive to determining that the abnormal condition exists.

Abstract: Aspects include a multistage collector to receive outputs from plural processing elements. Processing elements may comprise (each or collectively) a plurality of clusters, with one or more ALUs that may perform SIMD operations on a data vector and produce outputs according to the instruction stream being used to configure the ALU(s). The multistage collector includes substituent components each with at least one input queue, a memory, a packing unit, and an output queue; these components can be sized to process groups of input elements of a given size, and can have multiple input queues and a single output queue. Some components couple to receive outputs from the ALUs and others receive outputs from other components. Ultimately, the multistage collector can output groupings of input elements. Each grouping of elements (e.g., at input queues, or stored in the memories of component) can be formed based on matching of index elements.

Abstract: A pharmaceutical formulation comprising exosomes derived from mobilized stem cells, and one or more pharmaceutically acceptable carriers, adjuvants, or vehicles. A pharmaceutical formulation comprising a microvesicles derived from mobilized stem cells, and one or more pharmaceutically acceptable carriers, adjuvants, or vehicles. A pharmaceutical formulation comprising an exosome-derived and/or microvesicle derived molecule and one or more pharmaceutically acceptable carriers, adjuvants, or vehicles.

Abstract: This application concerns an apparatus comprising a housing arranged to be positioned at any one of a plurality of rotational angles, a display mounted to the housing and a processor arranged to execute instructions stored in a memory. The instructions are arranged to cause a user interface to be displayed on the display, to receive an indication of a rotation amount and rotation direction from a rotation input, rotate at least one corner element about its centre point by the rotation amount in the rotation direction and if the rotation amount is greater than a first predetermined limit, move the at least one corner element to a different one of a plurality of corner portions of the display.

Abstract: In at least one embodiment there is an implant for a spine comprising a frame having at least one face having a plurality of ribs. Inside of the frame there is a lattice. In addition, there is at least one opening in the frame exposing said lattice, wherein said lattice extends beyond said frame to form greater interactions with adjacent bone structure. In addition there can also be a process for producing an implant comprising: determining a size of an implant frame; determining a size of an implant lattice; determining an orientation of the implant in a body; determining a first orientation of a lattice inside of the frame; graphically forming the implant; determining the opacity of the lattice inside of the frame from a first viewpoint; reorienting the lattice inside of the frame; determining the opacity of the lattice at a second orientation; determining which orientation results in lower opacity; and selecting the lattice orientation at a lower opacity.

Abstract: A structured query language server may receive a command from a backup control server to provision a virtual device and perform a backup operation on the structured query language server. The structured query language server may be configured to write data to the virtual device in order to be transmitted to a data storage service. The backup and restore operations directed to the structured query language server may include a web service application programming interface request to the data storage service to cause the data written to the virtual device to be stored as a data object in the data storage service.

Abstract: Some embodiments relate to an apparatus for holding a workpiece under tension while one or more operations are performed on the workpiece, the apparatus comprising: a frame; a first spindle rotatably coupled to the frame; a first coupler configured to couple the first spindle to a first end of the workpiece; a second spindle rotatably coupled to the frame; and a second coupler configured to couple the second spindle to a second end of the workpiece; wherein a distance between the first and second couplers is adjustable to hold the workpiece under tension between the couplers while the one or more operations are performed, and wherein the workpiece can be rotated with the couplers relative to the frame about a common axis of rotation extending between the couplers. Some embodiments relate to a system comprising a controller for controlling rotation of the workpiece. Embodiments also relate to processes comprising holding a workpiece under tension while performing one or more operations on the workpiece.

Abstract: A customizable multi-stage fluid treatment assembly typically includes a connector, a plurality of cartridges, and a cap. The plurality of cartridges have a treatment medium spaced within an interior volume of the individual cartridges, between the ends thereof. The ends of the plurality of cartridges are configured to receive a fluid, bring the fluid into operative contact with the treatment medium, and dispense the fluid from the opposing end of the cartridge. The connector is coupled with one end of the plurality of cartridges and has an inlet and an outlet for receiving and dispensing the fluid to and from an appliance. The cap is coupled with the other end of the plurality of cartridges, enclosing the fluid treatment assembly, which is configured to be received in a cavity of an appliance. The cartridges of the plurality of cartridges may be individually replaced with cartridges to meet customized needs.

Abstract: A patient interface for delivering breathable gas to a patient includes a nasal prong assembly including a pair of nasal prongs structured to sealingly communicate with nasal passages of a patient's nose in use and headgear to maintain the nasal prong assembly in a desired position on the patient's face. The headgear includes side straps and rigidizers provided to respective side straps. Each rigidizer includes a first end portion that provides a connector structured to engage a respective end of the nasal prong assembly and an inwardly curved protrusion in the form of a cheek support that curves inwardly of the connector. The cheek support is adapted to follow the contour of the patient's cheek and guide a respective end portion of the side strap into engagement with the patient's cheek to provide a stable cheek support.

Abstract: Head-mounted display visor assembly. A head mounted display visor assembly includes a molded world-facing visor coupled to a separately molded user-facing bathtub. The visor includes an IR opaque and visual light opaque portion coupled to a separately manufactured IR permissive portion. The visor also includes an IR opaque portion. The bathtub includes an IR permissive, but visual light opaque portion and a visual light permissive portion.

Abstract: A printing machine 1 comprises a processor (2a) and a memory (2b, 2c) storing computer readable instructions. The computer readable instructions are arranged to cause the processor (2a) to generate access request data for processing by an access control server (3), receive access response data responsive to the access request data, process the access response data to determine a first print type and a first print quantity indicated by the access response data, and update, responsive to processing the access response data, an access status in the memory to indicate a second print quantity for the first print type.

Abstract: A mask system for use between a patient and device to deliver a breathable gas to the patient includes a mouth cushion, a pair of nasal prongs, an elbow, and a headgear assembly. The mouth cushion is structured to sealingly engage around an exterior of a patient's mouth in use, and the pair of nasal prongs are structured to sealingly communicate with nasal passages of a patient's nose in use. The elbow delivers breathable gas to the patient. The headgear assembly maintains the mouth cushion and the nasal prongs in a desired position on the patient's face. The headgear assembly provides a substantially round crown strap that cups the parietal bone and occipital bone of the patient's head in use.

Abstract: Methods and apparatuses related to a two-step RACH procedure are provided. Channel conditions can be estimated based on a UE PRACH transmission rather than the subsequent PUSCH transmission in the first part of the two-step RACH. A variable length gap can be provided between the PRACH preamble transmission and the PUSCH transmission. Other solutions are also provided.

Abstract: The technology provides decoupling an aspheric optical element from a birdbath optical element in a near-eye display (NED) device. One or more aspheric lens are used with a spherical birdbath reflective mirror in a projection light engine of a NED device. A projection light engine provides image light (or other information), by way of the spherical birdbath reflective mirror and at least one aspheric lens, to a near-eye display of the NED device. The spherical birdbath reflective mirror collimates and reflects the image light to an exit pupil external to the projection light engine. Decoupling the aspheric optical element from the spherical birdbath reflective mirror may enable high modulation transfer function (MTF) and improved manufacturability of the projection light engine. The NED device having aspheric optical elements decoupled from a birdbath optical element may be positioned by a support structure in a head-mounted display (HMD) or head-up display (HUD).

Abstract: A method for increasing temperature of a battery pack includes determining whether a temperature of a cell in the battery pack is above a lower threshold temperature. The method further includes charging, by a current directly from a charger, a balancing circuit including a resistor in proximity to the cell. The method also includes increasing the temperature of the cell in the battery pack.

Abstract: A breathing arrangement includes a patient interface, at least one inlet conduit, and a headgear assembly. The patient interface includes a mouth covering assembly including a cushion structured to sealingly engage around exterior of a patient's mouth in use, a nozzle assembly including a pair of nozzles structured to sealingly engage within nasal passages of a patient's nose in use, and a flexible element connecting the mouth covering assembly and the nozzle assembly. The at least one inlet conduit is structured to deliver breathable gas into at least one of the mouth covering assembly and the nozzle assembly for breathing by the patient. The headgear assembly is removably connected to at least one of the mouth covering assembly and the nozzle assembly so as to maintain the mouth covering assembly and the nozzle assembly in a desired position on the patient's face.

Abstract: Disclosed are methods and systems for credential protection. In one aspect, a method includes receiving an authentication credential and an authentication domain. A determination is made as to whether the authentication domain is permitted or unpermitted for authentication by the credential. If the domain is unpermitted, a data store is searched to identify a permitted domain for the credential. The credential is compared against credentials information associated with the domain to determine if it matches any of the associated credentials. If a match is found, an event is instantiated for the account.

Abstract: A battery pack configured for discharging to a desired state of charge (SoC) after a fault event that includes a plurality of battery cells and a balancing circuit connected to each of the battery cells. The balancing circuit is configured to measure operational values of each of the battery cells. The battery pack further includes a microcontroller configured to receive the operational values from the balancing circuit, compare the operational values to a prescribed threshold values and issue commands to selectively discharge one or more of the battery cells across the balancing circuit.