Patents by Inventor Steven Jungles

Steven Jungles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS OF TRIGLYCERIDES AND USES THEREOF
    Publication number: 20250120934
    Abstract: The present invention includes solid compositions of triglycerides with one or more fatty acids, such as triheptanoin and glycerol phenylbutyrate, and therapeutic use thereof. The solid compositions can be prepared by spray-drying or other processes.
    Type: Application
    Filed: December 26, 2024
    Publication date: April 17, 2025
    Inventors: John KLOPP, Gabrielle MORRIS, Emil KAKKIS, Steven JUNGLES
  • COMPOSITIONS OF TRIGLYCERIDES AND USES THEREOF
    Publication number: 20250120935
    Abstract: The present invention includes solid compositions of triglycerides with one or more fatty acids, such as triheptanoin and glycerol phenylbutyrate, and therapeutic use thereof. The solid compositions can be prepared by spray-drying or other processes.
    Type: Application
    Filed: December 26, 2024
    Publication date: April 17, 2025
    Inventors: John KLOPP, Gabrielle Morris, Emil Kakkis, Steven Jungles
  • COMPOSITIONS OF TRIGLYCERIDES AND USES THEREOF
    Publication number: 20250120936
    Abstract: The present invention includes solid compositions of triglycerides with one or more fatty acids, such as triheptanoin and glycerol phenylbutyrate, and therapeutic use thereof. The solid compositions can be prepared by spray-drying or other processes.
    Type: Application
    Filed: December 26, 2024
    Publication date: April 17, 2025
    Inventors: John KLOPP, Gabrielle MORRIS, Emil Kakkis, Steven JUNGLES
  • LYOPHILIZED ENPP1 POLYPEPTIDE FORMULATIONS AND USES THEREOF
    Publication number: 20250073319
    Abstract: In certain aspects, the present invention provides novel lyophilized formulations of ENPP1 polypeptides, as well as methods for using such lyophilized formulations and reconstituted formulations of ENPP1 to treat an indication associated an ENPP1 deficiency. The formulations and methods provided herein are useful in treating diseases associated with an ENPP1 deficiency such as pathological calcification or pathological ossification.
    Type: Application
    Filed: March 21, 2024
    Publication date: March 6, 2025
    Inventor: Steven Jungles
  • SIALYLATED GLYCOPROTEIN COMPOSITIONS AND USES THEREOF
    Publication number: 20240245759
    Abstract: The present application relates to sialylated glycoprotein compositions and methods of their use in treating various conditions and disorders.
    Type: Application
    Filed: December 7, 2023
    Publication date: July 25, 2024
    Inventors: Steven JUNGLES, Gabrielle MORRIS, Jeff GRUBB, Michael VELLARD, Emil D. KAKKIS
  • LIVER SPECIFIC PRODUCTION OF ENPP1 OR ENPP3
    Publication number: 20240148907
    Abstract: The present disclosure provides, among other things, vectors for expression of ENPP1 or ENPP3 in vivo and methods for the treatment of diseases of calcification and ossification in a subject.
    Type: Application
    Filed: April 7, 2023
    Publication date: May 9, 2024
    Inventors: Steven Jungles, Demetrios Braddock
  • SOLUBLE ENPP1 PROTEINS AND USES THEREOF
    Publication number: 20230313158
    Abstract: In certain aspects, the present invention provides novel soluble ENPP1 or ENPP3 polypeptides, as well as compositions and methods for using those variants to treat an indication associated an ENPP1 or ENPP3 deficiency. The compositions and methods provided herein are useful in treating diseases associated with an ENPP1 or ENPP3 deficiency such as pathological calcification or pathological ossification.
    Type: Application
    Filed: December 8, 2022
    Publication date: October 5, 2023
    Inventors: Zhiliang Cheng, Demetrios Braddock, Paul Stabach, Steven Jungles
  • SOLID COMPOSITIONS OF TRIGLYCERIDES AND USES THEREOF
    Publication number: 20230181513
    Abstract: The present invention includes solid compositions of triglycerides with one or more fatty acids, such as triheptanoin and glycerol phenylbutyrate, and therapeutic use thereof. The solid compositions can be prepared by spray-drying or other processes.
    Type: Application
    Filed: February 10, 2023
    Publication date: June 15, 2023
    Inventors: John KLOPP, Gabrielle Morris, Emil KAKKIS, Steven JUNGLES
  • TREATMENT OF DISEASES INVOLVING DEFICIENCY OF ENPP1 OR ENPP3
    Publication number: 20230031809
    Abstract: The present disclosure provides, among other things, vectors for expression of ENPP1 or ENPP3 in vivo and methods for the treatment of diseases of calcification and ossification in a subject.
    Type: Application
    Filed: August 25, 2022
    Publication date: February 2, 2023
    Inventors: Steven Jungles, Demetrios Braddock
  • SIALYLATED GLYCOPROTEIN COMPOSITONS AND USES THEREOF
    Publication number: 20220202915
    Abstract: The present application relates to sialylated glycoprotein compositions and methods of their use in treating various conditions and disorders.
    Type: Application
    Filed: November 11, 2021
    Publication date: June 30, 2022
    Inventors: Steven JUNGLES, Gabrielle MORRIS, Jeff GRUBB, Michael VELLARD, Emil D. KAKKIS
  • TREATMENT OF DISEASES INVOLVING DEFICIENCY OF ENPP1 OR ENPP3
    Publication number: 20210187067
    Abstract: The present disclosure provides, among other things, vectors for expression of ENPP1 or ENPP3 in vivo and methods for the treatment of diseases of calcification and ossification in a subject.
    Type: Application
    Filed: February 17, 2021
    Publication date: June 24, 2021
    Inventors: Steven Jungles, Demetrios Braddock
  • Sialic acid analogs
    Patent number: 10889607
    Abstract: The present invention provides sialic acid analogs and their compositions useful for the treatment of sialic acid deficiencies.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: January 12, 2021
    Assignee: Ultragenyx Pharmaceutical Inc.
    Inventors: Emil Kakkis, Steven Jungles, He Zhao
  • SIALYLATED GLYCOPROTEIN COMPOSITONS AND USES THEREOF
    Publication number: 20200282028
    Abstract: The present application relates to sialylated glycoprotein compositions and methods of their use in treating various conditions and disorders.
    Type: Application
    Filed: January 9, 2020
    Publication date: September 10, 2020
    Inventors: Steven JUNGLES, Gabrielle MORRIS, Jeff GRUBB, Michael VELLARD, Emil D. KAKKIS
  • SIALIC ACID ANALOGS
    Publication number: 20200131215
    Abstract: The present invention provides sialic acid analogs and their compositions useful for the treatment of sialic acid deficiencies.
    Type: Application
    Filed: September 16, 2019
    Publication date: April 30, 2020
    Inventors: Emil KAKKIS, Steven JUNGLES, He ZHAO
  • SOLID COMPOSITIONS OF TRIGLYCERIDES AND USES THEREOF
    Publication number: 20200069631
    Abstract: The present invention includes solid compositions of triglycerides with one or more fatty acids, such as triheptanoin and glycerol phenylbutyrate, and therapeutic use thereof. The solid compositions can be prepared by spray-drying or other processes.
    Type: Application
    Filed: June 19, 2019
    Publication date: March 5, 2020
    Inventors: John KLOPP, Gabrielle MORRIS, Emil KAKKIS, Steven JUNGLES
  • Sialic acid analogs
    Patent number: 10457701
    Abstract: The present invention provides sialic acid analogs and their compositions useful for the treatment of sialic acid deficiencies.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: October 29, 2019
    Assignee: Ultragenyx Pharmaceutical Inc.
    Inventors: Emil Kakkis, Steven Jungles, He Zhao
  • SIALIC ACID ANALOGS
    Publication number: 20190127409
    Abstract: The present invention provides sialic acid analogs and their compositions useful for the treatment of sialic acid deficiencies.
    Type: Application
    Filed: July 31, 2018
    Publication date: May 2, 2019
    Inventors: Emil KAKKIS, Steven JUNGLES, He ZHAO
  • SIALYLATED GLYCOPROTEIN COMPOSITIONS AND USES THEREOF
    Publication number: 20190054153
    Abstract: The present application relates to sialylated glycoprotein compositions and methods of their use in treating various conditions and disorders.
    Type: Application
    Filed: April 2, 2018
    Publication date: February 21, 2019
    Inventors: Steven JUNGLES, Gabrielle MORRIS, Jeff GRUBB, Michael VELLARD, Emil D. KAKKIS
  • Sialic acid analogs
    Patent number: 10065981
    Abstract: The present invention provides sialic acid analogs and their compositions useful for the treatment of sialic acid deficiencies.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: September 4, 2018
    Assignee: Ultragenyx Pharmaceutical Inc.
    Inventors: Emil Kakkis, Steven Jungles, He Zhao
  • Sialylated glycoprotein compositions and uses thereof
    Patent number: 9937243
    Abstract: The present application relates to sialylated glycoprotein compositions and methods of their use in treating various conditions and disorders.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: April 10, 2018
    Assignee: Ultrageny x Pharmaceutical Inc.
    Inventors: Steven Jungles, Gabrielle Morris, Jeff Grubb, Michael Vellard, Emil D. Kakkis