Abstract: Techniques to indicate whether datum transferred from a memory device to a second device is likely to be accessed again by the second device. The second device may include a buffer memory to store the datum when the datum is indicated as likely to be accessed again. If the second device is to access the datum again after receipt from the memory device, the second device may retrieve the datum from the buffer memory instead of from the memory device. Accordingly, multiple accessed of datum transferred once from an external memory are possible.

Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.

Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.

Abstract: A system, method, and apparatus are provided for external device-based prefetching mechanism. According to one embodiment, a packet is received at a network interface card in communication with a host computer system and a network. The packet is received from the network and includes a context as indicated by a packet address. Then, lookup in packet context table is performed. If a match is found, the received packet is associated with host memory addresses that are sent by the NIC to the processor as prefetch directives. The packet is then forwarded to the host computer system.

Abstract: A signal conditioning circuit is described which can facilitate dual mode use of a connector circuit, e.g., audio mode or data mode. In other words, a headset or alternatively, a data interface may be coupled to the connector circuit and signal conditioning circuit, depending on the mode of the device. In accordance with this disclosure, the signal conditioning circuit operates in audio mode without the need for conventional blocking capacitors in the speaker channels. Moreover, in some embodiments, the signal conditioning circuit also provides backwards compatibility with conventional connector circuits that include such blocking capacitors.

Abstract: A system and method for processing a packet such as an inbound RDMA write packet in a network communication system. When processing the packet, a prefetch may retrieve a header of the next packet or, in the case of the inbound RDMA write packet, the prefetch may additionally retrieve an inbound RDMA send context. Subsequent to the prefetch beginning, processing of the packet may be completed and much of the overhead for processing of the next packet may have already completed. Other embodiments are also described.

Abstract: A compound of the formula (I): or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.

Abstract: A dispenser for retaining electrical wire by standing on a floor or mounting on a wall stud, the dispenser has a support assembly for providing a base for use on a floor, a bracket assembly for coupling to a wall stud and a central mast assembly for holding the electrical wire. The central mast assembly selectively mount upright upon the support assembly and the bracket assembly.

Abstract: Disclosed are improved methods and apparatus for radiolabeling, particularly methods and apparatus for large scale in-line radiolabeling of products, such as proteins and antibodies.

Abstract: A dispenser retains a plurality of elongated items such as tie wraps while permitting convenient, quick and easy access. The dispenser includes a housing that defines a chute. A strap attaches to the housing to enclose the chute and, in turn, retain the items. During removal of items, a holding tension is maintained on the remaining items. After emptying, the dispenser can be refilled and used repeatedly. A ball joint couples a mounting feature to the housing so that the dispenser can be mounted at a desirable location and adjusted to a desirable dispensing position.

Abstract: The instant invention discloses a process for the synthesis of substituted indole cell proliferation inhibitors.

Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.

Abstract: The present invention relates to the preparation of chiral glucocorticoid receptor agents via biaryl atropisomers.

Abstract: Disclosed herein is a process for the preparation of erythromycin derivatives, or pharmaceutically acceptable salts thereof, which contain an optionally substituted propargyl group at the 6-O-position.

Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.

Abstract: The invention is directed to inventory management associated with providing components and materials (“components”) to customers, with particular regard to monitoring and managing value-added services, for example programming, assembly and aggregating services that are performed on the components, and further to disseminating information directed to inventory management. The present invention effectively reduces the required number of inventory storage locations compared to prior inventory management systems. Additionally, information sharing directed to customer demands, inventory levels, advance shipping notices, work in process, and delivery and replenishment is improved by processes of the present invention. Moreover, the invention provides direct replenishment of inventory after components are delivered to customers.

Abstract: The instant invention discloses a process for the synthesis of substituted indole cell proliferation inhibitors.

Abstract: The present invention relates to the preparation of chiral glucocorticoid receptor agents via biaryl atropisomers.

Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.

Abstract: A compound of the formula (I): or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.