Abstract: Fibrous structures comprising spunbond filaments and solid additives and methods for making such fibrous structures are provided.

Abstract: A vibrating and sound baby mat is an apparatus that effectively comforts an infant. The apparatus includes a plurality of covers, a reinforcing pad, a recorder, a speaker, a vibrating unit, a control panel, and a processing unit. The plurality of covers protects the reinforcing pad, the vibrating unit, and the processing unit from getting damaged. The reinforcing pad upholds and supports an infant. The recorder detects a sound, preferably a heartbeat, and the speaker continuously emits the detected sound. Similarly, the vibrating unit emits vibrations based on the detected sound. In order to better represent the sound, the apparatus may further include an electrocardiogram module and a plurality of electrocardiogram sensors. The control panel engages and controls the recorder, the speaker, the vibrating unit, and the electrocardiogram module. The processing unit allows the recorder, the speaker, the vibrating unit, and the electrocardiogram module to communicate with each other.

Abstract: Embodiments of the present disclosure generally relate to custom-fit in-ear audio devices. The custom-fit earpieces disclosed herein may include features providing superior retention in a user's ear while also maintaining desirable comfort and sound quality. The superior retention is generally provided by a curable filler disposed in a bladder that is deformed to conform to the shape of a user's outer ear as the filler material is cured. It has been found that a desired comfort level and sound quality can be achieved in a custom-fit earpiece by physically separating or at least partially decoupling the audio output member from other portions of the earpiece that are designed to enable the retention of the custom-fit earpiece within the user's ear.

Abstract: A method for determining the location of a frequency receiver device with respect to at least two frequency originator devices, each of a current location, the method including synchronizing a clock of the frequency receiver device with a clock of one of the at least two frequency originator devices; receiving by the frequency receiver device, a message including an identification code configured for identifying one of the at least two frequency originator devices and obtaining a broadcast time and a current location of the one of the at least two frequency originator devices by looking up a table correlating the at least two frequency originator devices and their respective broadcast times and current locations; calculating a time of flight of the message by calculating the difference between a receive time at which the message is received by the frequency receiver device and the broadcast time.

Abstract: Fibrous structures that exhibit a novel combination of properties and to methods for making such fibrous structures are provided.

Abstract: The present invention is directed to a nucleic acid molecule comprising a polynucleotide sequence encoding a chimeric antigen receptor comprising (a) an anti-CLEC14A binding domain, (b) a transmembrane domain and (c) an intracellular signalling domain; wherein said anti-CLEC14A binding domain is capable of binding to the C-type lectin domain of CLEC14A. The invention further provides a chimeric antigen receptor encoded by the nucleic acid molecule, a vector comprising the nucleic acid molecule, a cell comprising the nucleic acid molecule, vector or CAR and the therapeutic use of the nucleic acid, vector or cell, particularly in treating CLEC14A expressing conditions.

Abstract: The present invention relates to an isolated antibody, which selectively binds to CLEC14A, wherein said antibody (a) comprises at least one heavy chain variable region that comprises three CDRs and at least one light chain variable region that comprises three CDRs, wherein said heavy chain variable region comprises:(i) a variable heavy (VH) CDR1 that has the amino acid sequence of SEQ ID NO. 105, preferably of SEQ ID NO: 2 or 42; (ii) a VH CDR2 that has the amino acid sequence of SEQ ID NO. 106, preferably of SEQ ID NO: 3 or 43; and/or (iii) a VH CDR3 that has the amino acid sequence of SEQ ID NO. 107, preferably of SEQ ID NO: 4 or 44; and/or wherein said light chain variable region comprises: (iv) a variable light (VL) CDR1 that has the amino acid sequence of SEQ ID NO. 108, preferably of SEQ ID NO: 6 or 46; (v) a VL CDR2 that has the amino acid sequence of SEQ ID NO. 109, preferably of SEQ ID NO: 7 or 47; and/or (vi) a VL CDR3 that has the amino acid sequence of SEQ ID NO.

Abstract: Articles, such as sanitary tissue products, including fibrous structures, and more particularly articles including fibrous structures having a plurality of fibrous elements wherein the article exhibits differential cellulose content throughout the thickness of the article and methods for making same are provided.

Abstract: Tools and techniques for the rapid, continuous, invasive and/or noninvasive measurement, estimation, and/or prediction of a patient's physiological state. In an aspect, some tools and techniques can estimate predict the onset of conditions intracranial pressure, an amount of blood volume loss, cardiovascular collapse, and/or dehydration. Some tools can recommend (and, in some cases, administer) a therapeutic treatment for the patient's condition. In another aspect, some techniques employ high speed software technology that enables active, long term learning from extremely large, continually changing datasets. In some cases, this technology utilizes feature extraction, state-of-the-art machine learning and/or statistical methods to autonomously build and apply relevant models in real-time.

Abstract: A magnetic refrigeration apparatus includes one or more beds of magnetocaloric material arranged along a circumferential direction. The apparatus also includes a heat transfer fluid, one or more hot side heat exchangers (HHEX), one or more pumps or fluid displacement devices configured to move the heat transfer fluid, and a magnetic-field source. The magnetic-field source generates magnetic flux oriented substantially in a radial direction through the beds. The field source advantageously includes one or more pole pieces, one or more axial-end magnets, and one or more axial-end flux return pieces. Additionally, one or more circumferential flux returns, one or more gap flux return pieces, one or more side magnets, and one or more side flux return pieces can be added to increase system performance and reduce cost.

Abstract: A magnetic refrigeration apparatus according to the present disclosure includes a magnetic-field source and two or more bed rings. The bed rings can be arranged in pairs with shared cold and hot fluid plenums. A flow of heat transfer fluid may pass at least partially radially through the shared fluid plenum or through a connection between the fluid plenum and one or more flow tubes. The MR apparatus and systems of the present disclosure may further include one or more circumferential flux returns with radial through-hole passageways to accommodate flow tubing. For apparatus configurations with an even number of bed rings, the axial dimension of the passageways may be smaller than the circumferential dimension of the passageways.

Abstract: Articles, for example multi-ply fibrous structure-containing articles such as multi-ply sanitary tissue products, containing two or more fibrous structure plies, and more particularly to multi-ply articles containing two or more fibrous structure plies having a plurality of fibrous elements wherein the articles exhibit improved bulk and absorbent properties compared to known articles and methods for making same, are provided.

Abstract: Articles, for example multi-ply fibrous structure-containing articles such as multi-ply sanitary tissue products, containing two or more fibrous structure plies, wherein at least one of the fibrous structure plies is embossed and is bonded to at least one other fibrous structure ply by a water-resistant bond such that void volume is created between the bonded fibrous structure plies.

Abstract: Articles, for example multi-ply fibrous structure-containing articles such as multi-ply sanitary tissue products, containing two or more fibrous structure plies, and more particularly to multi-ply articles containing two or more fibrous structure plies having a plurality of fibrous elements wherein the articles exhibit improved bulk and absorbent properties compared to known articles and methods for making same, are provided.

Abstract: An improved self-propelled grain harvester and threshing machine characterized by the sieves, cleaning fan and grain tank being beneath the grain harvester's threshing system which puts the center of gravity in the bottom of the machine and eliminates the need for conveying the grain throughout the machine for cleaning and to the top of the machine for storage. This configuration eliminates several clean grain conveying systems and reduces the length of the reprocess tailings elevator giving the machine a safe low profile and center of gravity when the machine is empty and the center of gravity lowers as the grain tank fills.

Abstract: An integrated circuit and method with dual stress liners and with NMOS transistors with gate overhang of active that is longer than the minimum design rule and with PMOS transistors with gate overhang of active that are not longer than the minimum design rule.

Abstract: Disclosed is a process for producing cholesterol from fish oil, including the following steps: (a) distilling fish oil in a vacuum distillation column to obtain a first residue and a first distillate, (b) distilling the first distillate in a vacuum distillation column to obtain a second distillate and a second residue, (c) contacting the second residue with an alkali to produce a saponified mixture, (d) contacting the saponified mixture with a non-polar organic solvent or a mixture of non-polar organic solvents to produce an organic phase and an aqueous phase, (e) separating the organic phase from the aqueous phase, (f) cooling the organic phase to form a solid phase and a liquid phase, and (g) separating the solid phase from the organic phase, wherein the separated solid phase includes cholesterol.

Abstract: Electronic design automation (EDA) systems, methods, and computer readable media are presented for adding design for test (DFT) logic at register transfer level (RTL) into an integrated circuit (IC) design at RTL. In some embodiments, the DFT logic at RTL includes a port that connects to a hierarchical reference with a hierarchical path in the tree structure hierarchy to a part of the IC design at RTL. Such DFT modification helps to decrease the number of new ports added at this stage, and as a result assists subsequent debugging and back-annotation of RTL.

Abstract: An apparatus includes an end cap capable of supporting numerous antenna configurations and securing connectors without the use of additional hardware. An end cap assembly for connecting a cable to the end cap comprises the end cap including one or more flanges, wherein each of the one or more flanges includes a plurality of edges defining a cavity, the plurality of edges being configured to mate with a portion of a connector, and a flange nut including a first plurality of serrations configured to mate with a second plurality of serrations on an outside of the end cap, wherein the flange nut and the flange are formed so as to allow for attachment of the cable to the end cap.