Abstract: A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2 and R3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.

Abstract: Various disclosed embodiments include illustrative controller units, direct current fast charging (DCFC) units, and methods. In an illustrative embodiment, a controller unit includes a controller and a memory configured to store computer-executable instructions. The computer-executable instructions are configured to cause the controller to determine status of a power electronics module (PEM) of a direct current fast charging (DCFC) unit, and instruct the PEM to control power quality of a three-phase alternating current (AC) grid power signal in response to the determined status being available.

Abstract: A vehicular occupant monitoring system includes a camera disposed at an interior rearview mirror of a vehicle. The camera includes an imaging array sensor and a lens. The lens is disposed at the imaging array sensor with a center axis of the lens vertically offset from a center region of the imaging array sensor. A center region of the lens is disposed at and images at a lower region of the imaging array sensor when the camera is disposed at the interior rearview mirror and an upper peripheral region of the lens images at the center region and a lower region of the imaging array sensor when the camera is disposed at the interior rearview mirror. The vehicular occupant monitoring system, responsive to processing by the image processor of image data captured by the camera, determines presence of an occupant of the vehicle.

Abstract: A protective film that can be included in multi-layer film laminates for use in marketing, advertising campaigns, particularly outdoor or other environment impacted promotions and safety applications. The film includes at least two different polyurethane polymers and is free or substantially free of polyvinyl chloride based polymer. One polyurethane has an ultimate elongation less than 200%, and another polyurethane has an ultimate elongation more than 400%. The film may be transparent, translucent, clear or have other desirable optical properties.

Abstract: A vehicle battery pack includes several supporting beams extending in a first direction; and battery modules located between the supporting beams. The battery module comprises: a base plate extending in the first direction; multiple battery cells arranged in a stacked manner and placed on the base plate; and end plates connected to the base plate, the end plates compress the multiple battery cells from both sides in the first direction. The battery cell has end faces facing a second direction and the end faces are adjacent to the supporting beams. A vehicle can include the aforementioned vehicle battery pack.

Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

Abstract: Machine learning, artificial intelligence, and other computer-implemented methods are used to identify various semantically important chunks in documents, automatically label them with appropriate datatypes and semantic roles, and use this enhanced information to assist authors and to support downstream processes. Chunk locations, datatypes, and semantic roles can often be automatically determined from what is here called “context”, to wit, the combination of their formatting, structure, and content; those of adjacent or nearby content; overall patterns of occurrence in a document, and similarities of all these things across documents (mainly but not exclusively among documents in the same document set).

Abstract: A framework for an automated news recommendation system for financial analysis. The system includes the automated ingestion, relevancy, clustering, and ranking of news events for financial analysts in the capital markets. The framework is adaptable to any form of input news data and can seamlessly integrate with other data used for analysis like financial data.

Abstract: Methods of treating autoimmune diseases, such as systemic lupus erythematosus using domain antibodies that specifically bind human CD28 are provided. The methods may comprise at least one administration cycle comprising one dose of the domain antibody. The method reduces symptoms of systemic lupus erythematosus compared to placebo.

Abstract: Various disclosed embodiments include illustrative controller modules, direct current (DC) fast charging devices, and methods. In an illustrative embodiment, a controller module for a DC-DC converter includes a controller and computer-readable media configured to store computer-executable instructions configured to cause the controller to receive an input voltage Vin to the DC-DC converter, receive an output DC voltage Vo from the DC-DC converter, generate control signals configured to control a charging output of the DC-DC converter responsive to the received input voltage Vin and output voltage Vo, and output the generated control signals to the DC-DC converter.

Abstract: In accordance with an embodiment, described herein is a system and method for supporting patching in a multi-tenant application server environment. The system can associate one or more partitions with a tenant, for use by that tenant, wherein a partition is a runtime and administrative subdivision or slice of a domain. A patching process can take advantage of high-availability features provided by an application server clustering environment, to apply patches in a controlled, rolling restart, which maintains a domain's ability to operate without interruption, or with zero downtime. The process can be used to automate complex or long running tasks, including preserving an unpatched or prior version of an application server, application, or other software component for possible rollback, or providing automatic reversion in the event of an unrecoverable error.

Abstract: The disclosure provides a method for universal naming convention (UNC) path redirection between a local desktop and a remote desktop. The method generally includes selecting, by a client device in an internal network, via an application running on a remote desktop in an external network, to open a UNC path for a resource located in the internal network. A firewall restricts the external network to access the resource located in the internal network. The method generally includes receiving, at the client device, from the remote desktop, via a virtual channel between the external network and the client device in the internal network, a message indicating to open the UNC path. The method generally includes opening, by the client device, via a local application of the client device, the UNC path to access the resource located in the internal network.

Abstract: The present invention relates to a method and apparatus for detecting a signal propagation type, the method comprises: when a positioning base station of an ultra-wideband positioning system currently receives a pulse response from a positioning tag, computing an actual value of a specified feature of the received pulse response at least using the received pulse response; selecting, for the specified feature, a predictive model for predicting an adopted value of the specified feature at a future moment on the basis of an adopted value of the specified feature at a historical moment; using the predictive model selected for the specified feature to acquire an adopted value of the specified feature at a future moment, to serve as a predicted value of the specified feature of the received pulse response; and determining the current type of signal propagation between the positioning base station and positioning tag on the basis of the actual value and predicted value of the specified feature of the received pulse

Abstract: Disclosed are various approaches for recommending remotely executed applications for opening files. In one approach, an indication is received that a user desires to open the local file of a client device remotely. At least one remotely executed application is identified to open the local file remotely. A user interface is rendered by the client device that facilitates selection from among the remotely executed application(s). A user selection of a particular remotely executed application generated through the user interface is received. The particular remotely executed application opens the local file remotely.

Abstract: In accordance with an embodiment, described herein is a system and method for supporting patching in a multi-tenant application server environment. The system can associate one or more partitions with a tenant, for use by that tenant, wherein a partition is a runtime and administrative subdivision or slice of a domain. A patching process can take advantage of high-availability features provided by an application server clustering environment, to apply patches in a controlled, rolling restart, which maintains a domain's ability to operate without interruption, or with zero downtime. The process can be used to automate complex or long running tasks, including preserving an unpatched or prior version of an application server, application, or other software component for possible rollback, or providing automatic reversion in the event of an unrecoverable error.

Abstract: The present invention relates to a method and apparatus for detecting a signal propagation type. The method comprises: calculating a similarity value of a currently received pulse response and a reference pulse response when a certain positioning base station of a UWB positioning system currently receives a pulse response from a certain positioning tag, the similarity value indicating the degree of similarity between the currently received pulse response and the reference pulse response, wherein the reference pulse response is a pulse response previously received by the positioning base station from the positioning tag; and determining the current type of signal propagation between the positioning base station and the positioning tag on the basis of the similarity value. The method and apparatus can detect the type of signal propagation between the positioning base station and positioning tag of the UWB positioning system.

Abstract: The disclosure relates to a detection method and a detection apparatus, the method including: calculating, when a location base station in an ultra-wideband location system receives a pulse response, values of a plurality of specified pulse response characteristics using the received pulse response, and using the calculated values as values of the plurality of specified pulse response characteristics of the location base station; calculating differences between the values of the plurality of specified pulse response characteristics of the location base station and values of the plurality of specified pulse response characteristics of the location base station at a previous time, and using the calculated differences as variations of the plurality of specified pulse response characteristics of the location base station; determining, based on at least the variations of the plurality of specified pulse response characteristics of the location base station and by means of a trained classifier, whether signal propa

Abstract: In accordance with an embodiment, described herein is a system and method for supporting patching in a multi-tenant application server environment. The system can associate one or more partitions with a tenant, for use by that tenant, wherein a partition is a runtime and administrative subdivision or slice of a domain. A patching process can take advantage of high-availability features provided by an application server clustering environment, to apply patches in a controlled, rolling restart, which maintains a domain's ability to operate without interruption, or with zero downtime. The process can be used to automate complex or long running tasks, including preserving an unpatched or prior version of an application server, application, or other software component for possible rollback, or providing automatic reversion in the event of an unrecoverable error.