Patents by Inventor Steven M. Cramer

Steven M. Cramer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Displacement chromatography of proteins using low molecular weight anionic displacers
    Patent number: 5606033
    Abstract: A method for the purification of proteins by displacement chromatography on ion exchange media using low molecular weight displacers is disclosed. Several classes of low molecular weight anionic species are exemplified, including aromatic rings having sulfonic acid or carboxylic acid moieties attached thereon, sulfated sugar derivatives, anionic antibiotics, and dendrimeric polymers. Novel compounds useful as displacers are dendrimers of formula ##STR1## wherein R.sup.1 is lower alkyl, n is 2 to 6 and similar dendritic polymers based thereon.
    Type: Grant
    Filed: October 19, 1995
    Date of Patent: February 25, 1997
    Inventors: Steven M. Cramer, James A. Moore, Amitava Kundu, Yufei Li, Guhan Jayaraman
  • Displacement chromatography of proteins using low molecular weight displacers
    Patent number: 5478924
    Abstract: A method for the purification of proteins by displacement chromatography on ion exchange media using low molecular weight displacers is disclosed. Several classes of low molecular weight, charged species are exemplified, including aminoacids, peptides, antibiotics and dendrimeric polymers. Novel compounds useful as displacers are dendrimers of formula ##STR1## wherein R.sup.1 is lower alkyl, n is 2 to 6, and X is a common counter anion and similar dendritic polymers based thereon.
    Type: Grant
    Filed: February 16, 1994
    Date of Patent: December 26, 1995
    Inventors: Steven M. Cramer, James A. Moore, Amitava Kundu, Yufei Li, Guhan Jayaraman