Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

Abstract: Embodiments that compensate for changes to sensor response characteristics (e.g., sensitivity) due to time durations are disclosed. The time durations can be the amount of time the sensor is in a post-manufacture packaged state prior to use, or the amount of time the sensor is in use. Sensor response changes due to other variables can also be compensated for.

Abstract: A radiotherapy system for treatment of skin includes a confocal microscopy imaging component and a photoacoustic microscopy imaging component to capture images of the skin of a patient at more than one depth. A processor combines images to produce a fused model for the region of interest, generates a plan for radiotherapy treatment based on the fused model, and controls the radiotherapy component for carrying out the radiotherapy treatment.

Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

Abstract: Embodiments that compensate for changes to sensor response characteristics (e.g., sensitivity) due to time durations are disclosed. The time durations can be the amount of time the sensor is in a post-manufacture packaged state prior to use, or the amount of time the sensor is in use. Sensor response changes due to other variables can also be compensated for.

Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

Abstract: An insulation blanket assembly for use on an aircraft includes a cover. The cover has an inboard material and an outboard material. The insulation blanket assembly also includes an insulation material between the inboard material and the outboard material. The insulation blanket assembly also includes one or more support rails attached to at least one of the cover or the insulation material. When the insulation blanket assembly is attached to the aircraft, the one or more support rails are configured to provide separation between an aircraft structure and the insulation material to reduce or eliminate moisture from transferring to the insulation material.

Abstract: Systems and methods for processing erasure requests are provided, namely requests from users to have their user data erased from a system. The system maintains user data in multiple components which may not be in communication with each other. With the provided system, certain entities, referred to herein as erasure control entities, are informed of details of received erasure requests, and are given the opportunity to provide input on whether they should be executed or note. For example, one erasure control entity, such as a credit card server, may not want an erasure request executed for a user with a large outstanding debt, while another erasure control entity, such as a legal component, may be unaware of this and may not be concerned with the erasure request being executed. The system and method ensure that erasure requests are not executed in situations that are premature or inappropriate.

Abstract: In some embodiments, the instant invention includes a computer-implemented method that includes: specifically programming at least one computer system to perform: automatically obtaining input financial data; automatically determining units of work that the input financial data can be organized into; automatically importing the input financial data into a database based on the units of work; automatically validating the imported input financial data, by: identifying deficient units of work based on predefined rules, where each deficient unit of work has a current data error; analyzing, based on research information, the current data error to determine a current corrective action to remedy the current data error; and verifying that the current corrective action does not result in: an additional deficient unit of work, an additional data error, and a change in at least one predefined data report; and automatically executing the current corrective action to remedy the current data error.

Abstract: A system for differential recording connectable to an electrical lead with at least two electrodes, including: the lead having a distal end; at least one amplifier electrically connectable to the at least two electrodes, wherein the at least one amplifier subtracts a signal recorded by one of the at least two electrodes, from a signal recorded by the other one of the at least two electrodes to generate a differential signal; a memory configured for storing said differential signal and reference indications of electrical signals associated with neural tissue; a processing circuitry for detection of an anatomical position, wherein the processing circuitry calculates an anatomical position of the electrical lead based on processing of the differential signal and the reference indications of electrical signals associated with the neural tissue.

Abstract: A system for differential recording connectable to an electrical lead with at least two electrodes, including: the lead having a distal end; at least one amplifier electrically connectable to the at least two electrodes, wherein the at least one amplifier subtracts a signal recorded by one of the at least two electrodes, from a signal recorded by the other one of the at least two electrodes to generate a differential signal; a memory configured for storing said differential signal and reference indications of electrical signals associated with neural tissue; a processing circuitry for detection of an anatomical position, wherein the processing circuitry calculates an anatomical position of the electrical lead based on processing of the differential signal and the reference indications of electrical signals associated with the neural tissue.

Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

Abstract: In some embodiments, the instant invention includes a computer-implemented method that includes: specifically programming at least one computer system to perform: automatically obtaining input financial data; automatically determining units of work that the input financial data can be organized into; automatically importing the input financial data into a database based on the units of work; automatically validating the imported input financial data, by: identifying deficient units of work based on predefined rules, where each deficient unit of work has a current data error; analyzing, based on research information, the current data error to determine a current corrective action to remedy the current data error; and verifying that the current corrective action does not result in: an additional deficient unit of work, an additional data error, and a change in at least one predefined data report; and automatically executing the current corrective action to remedy the current data error.

Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

Abstract: This invention provides an device for electrical stimulation of the spinal cord. The device has an electrode assembly with a sufficiently thin profile to be implanted between the pial surface of the spinal cord and the dura mater, and secured to the dura. Electrodes on the electrode assembly are directed towards the surface of the spinal cord, and connected through the dura to a signal generator located outside the dura. Following implantation, the subject is treated by transmitting electrical signals from the signal generator through the leads to the electrodes, stimulating the subject's spinal cord.

Abstract: This invention provides an device for electrical stimulation of the spinal cord. The device has an electrode assembly with a sufficiently thin profile to be implanted between the pial surface of the spinal cord and the dura mater, and secured to the dura. Electrodes on the electrode assembly are directed towards the surface of the spinal cord, and connected through the dura to a signal generator located outside the dura. Following implantation, the subject is treated by transmitting electrical signals from the signal generator through the leads to the electrodes, stimulating the subject's spinal cord.

Abstract: Embodiments that compensate for changes to sensor response characteristics (e.g., sensitivity) due to time durations are disclosed. The time durations can be the amount of time the sensor is in a post-manufacture packaged state prior to use, or the amount of time the sensor is in use. Sensor response changes due to other variables can also be compensated for.