Patents by Inventor Subas Man Sakya

Subas Man Sakya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE
    Publication number: 20230089073
    Abstract: Provided herein are GLP-1 receptor modulator compounds, pharmaceutical compositions, methods of their preparation, and methods of their use in treatment, and/or diagnosis.
    Type: Application
    Filed: January 27, 2022
    Publication date: March 23, 2023
    Inventors: Xiaohui DU, Ray Fucini, Xu Ran, Chien-Hung Yeh, Xiang Zhou, Rui Gao, Joon Won Jeong, Li Liu, Subas Man Sakya, Xiaofang Wang, Hiroyuki Kawai, Craig Lee, David Lloyd, Stig Hansen
  • Novel Heterocyclic Derivatives with Cardiomyocyte Proliferation Activity for Treatment of Heart Diseases
    Publication number: 20230025301
    Abstract: Provided are novel heterocyclic derivatives with cardiomyocyte proliferation activity for treatment of heart diseases. Specifically, provided are the compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates or prodrugs, preparation method thereof, application thereof and pharmaceutical composition useful for treatment of heart diseases.
    Type: Application
    Filed: December 14, 2020
    Publication date: January 26, 2023
    Inventors: Yihan Chen, Dandan Liang, Yi Liu, Subas Man Sakya, Xiang Li, Li Li, Huixing Zhou, Fulei Zhang, Xiaoyu He, Jinhua Yang
  • Ion Channel Antagonists/Blockers and Uses Thereof
    Publication number: 20230015875
    Abstract: Provided are ion channel antagonists/blockers and uses thereof. Specifically, it provides the compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates or prodrugs, preparation method therefor and application thereof. Definition of each group in the formula can be found in the specification for details. Provided is also pharmaceutical composition useful for treatment of heart disease and other ion channel related diseases.
    Type: Application
    Filed: December 14, 2019
    Publication date: January 19, 2023
    Inventors: Yihan Chen, Dandan Liang, Yi Liu, Subas Man Sakya, Jinhua Yang, Li Li, Duanyang Xie, Dan Shi, Ke Xiong
  • BENZIMIDAZOYL GLP-1 RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE
    Publication number: 20220396569
    Abstract: Provided herein are GLP-1 receptor modulator compounds, pharmaceutical compositions, methods of their preparation, and methods of their use in treatment, and/or diagnosis.
    Type: Application
    Filed: May 3, 2022
    Publication date: December 15, 2022
    Inventors: Xiaohui DU, Ray FUCINI, Xu RAN, Chien-Hung YEH, Xiang ZHOU, Subas Man SAKYA, Xiaofang WANG, Hiroyuki KAWAI, Craig LEE, Sumanta GARAI
  • Use of Heterocyclic Derivatives with Cardiomyocyte Proliferation Activity for Treatment of Heart Diseases
    Publication number: 20220378748
    Abstract: Provided herein is the use of heterocyclic derivatives with cardiomyocyte proliferation activity for treatment of heart diseases. Specifically, disclosed is the use of compounds of formula (I) or a pharmaceutically acceptable salt, a solvate, a stereoisomer or a prodrug thereof; and application thereof. Definition of each group in the formula can be found in the specification for details.
    Type: Application
    Filed: December 14, 2019
    Publication date: December 1, 2022
    Inventors: Yihan Chen, Dandan Liang, Yi Liu, Subas Man Sakya, Li Li, Fulei Zhang, Huixing Zhou, Xiaoyu He
  • Pyrazole ether derivatives as anti-inflammatory/analgesic agents
    Patent number: 6878726
    Abstract: The present invention relates to compounds of the formula: wherein R1, R2, R3, R4, R5, R6, R7, R8, A, X and Y are defined as in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals.
    Type: Grant
    Filed: March 2, 2001
    Date of Patent: April 12, 2005
    Assignee: Pfizer Inc.
    Inventors: Hengmaio Cheng, Subas Man Sakya, Jason Kenneth Dutra
  • Pyrazole ether derivatives as anti-inflammatory/analgesic agents
    Publication number: 20040259879
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: July 16, 2004
    Publication date: December 23, 2004
    Inventors: Hengmaio Cheng, Subas Man Sakya, Jason Kenneth Dutra
  • Pyrazole derivatives as anti-inflammatory/analgesic agents
    Patent number: 6538009
    Abstract: The present invention relates to compounds of the formula wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, n, p, W, X, Y and Z are defined as in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats, horses and livestock.
    Type: Grant
    Filed: April 2, 2001
    Date of Patent: March 25, 2003
    Assignee: Pfizer, Inc.
    Inventor: Subas Man Sakya
  • Pyrazole derivatives as anti-inflammatory/analgesic agents
    Publication number: 20020115856
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: April 2, 2001
    Publication date: August 22, 2002
    Inventor: Subas Man Sakya
  • Pyrazole ether derivatives as anti-inflammatory/analgesic agents
    Publication number: 20020058681
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: March 2, 2001
    Publication date: May 16, 2002
    Inventors: Hengmiao Cheng, Subas Man Sakya, Jason Kenneth Dutra
  • 3,6-ketal and enol ether macrolide antibiotics
    Patent number: 6043226
    Abstract: This invention relates to compounds of formulas 1 and 2 ##STR1## and to pharmaceutically acceptable salts and solvates thereof, wherein X, X.sup.1, R.sup.1, R.sup.2, R.sup.7, R.sup.17 and R.sup.19 are as defined herein. The compounds of formulas 1 and 2 may be useful in the treatment of bacterial, parasitic and protozoal infections, as well as disorders related to bacterial, parasitic and protozoal infections, in mammals, fish and birds. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and 2 and to methods of treating bacterial, parasitic and protozoal infections by administering the compounds of formula 1 and 2.
    Type: Grant
    Filed: February 25, 1999
    Date of Patent: March 28, 2000
    Assignee: Pfizer Inc.
    Inventors: Kristin Marie Lundy, Hengmiao Cheng, Martha L. Minich, Subas Man Sakya, Peter Bertinato