Abstract: The present invention relates to a biguanide derivative compound capable of effectively preventing and treating immune diseases. The biguanide-based derivative compound according to the present invention inhibits the generation of IL-17 and TNF-?, which are inflammatory cytokines, increases the activity of regulatory T cells having an immunomodulatory function, and exhibits excellent therapeutic effects in animal models of immune diseases. Accordingly, the biguanide-based derivative compound can be usefully used as an immunosuppressant or a pharmaceutical composition capable of preventing or treating various immune diseases, such as autoimmune diseases, inflammatory diseases, and transplant rejection, caused by the dysregulation of immune responses.

Abstract: The present invention relates to a pressure adjusting device which maintains the precision of pressure control even during use of the inkjet printer and the pressure adjusting device includes an output tube which is connected to an ink reservoir; at least one pressure generator which is capable of changing the pressure in the ink reservoir; an adjusting valve which is positioned between the pressure generator and the output tube; a control unit which controls the adjusting valve to control an output pressure; a pressure sensor which measures pressure information which is output to the output tube so that the control unit is capable of adjusting the adjusting valve; and a temperature sensor which measures temperature information so that the control unit is capable of performing a temperature correction with respect to the pressure information measured at the pressure sensor.

Abstract: The present invention relates to an ink container for an inkjet printer, the ink container being configured to prevent a problem caused by fine bubbles accumulated in the ink container. As the ink container containing ink for supplying ink to an inkjet head having a plurality of nozzles that discharge ink, the ink container includes: a bottom surface inclined so that a first side thereof connected to a return line through which ink is returned from the inkjet head is positioned higher than a second side thereof connected to a supply line through which ink is supplied to the inkjet head; and a bubble removing net provided between the supply line and the return line to remove bubbles from ink contained in the ink container.

Abstract: The present invention relates to a composition for treating osteoarthritis and a method for preparing the same, and more specifically, relates to a composition comprising hydrophilized sulfasalazine as an active ingredient and hyaluronic acid so as to enable effective treatment of osteoarthritis such as degenerative osteoarthritis by preventing joint wear in addition to symptom relief through intraarticular or local administration, and a method for preparing the same.

Abstract: A method and apparatus for interfacing a skinning weight of a 3D model surface for 3D model rigging is provided. The method includes generating a spline on the 3D model and computing a skinning weight of the 3D model based on the generated spline. The computing of the skinning weight includes calculating the skinning weight of the 3D model by minimizing energy which satisfies a predetermined constraint.

Abstract: A nozzle assembly, according to one embodiment of the present invention, comprises; a nozzle case; a nozzle provided in the nozzle case to move forward and backward, and having an ejection hole at one end thereof; and a moving guide member provided at the lower side of the nozzle case so as to reciprocate in the direction intersecting the longitudinal direction of the nozzle case, wherein the nozzle case is coupled to the moving guide member so as to rotate according to a reciprocating motion of the moving guide member.

Abstract: Provided is a display control method including: obtaining a first input of a user regarding a first region displayed on a display unit; activating an input reference object in the first region based on the first input; displaying an interface for manipulating the input reference object in a second region on the display unit based on the first input; obtaining a second input of the user regarding the interface; and changing a location of the input reference object in the first region based on the second input.

Abstract: Disclosed is a hot water generator comprising: a housing having a water inlet, a water outlet, and an inner space; and a heater disposed in the inner space of the housing, wherein the housing is provided with a helical flow formation unit which enables water flowing into the inner space to helically spin and flow along an outer surface of the heater.

Abstract: The present invention relates to a biguanide derivative compound capable of effectively preventing and treating immune diseases. The biguanide-based derivative compound according to the present invention inhibits the generation of IL-17 and TNF-?, which are inflammatory cytokines, increases the activity of regulatory T cells having an immunomodulatory function, and exhibits excellent therapeutic effects in animal models of immune diseases. Accordingly, the biguanide-based derivative compound can be usefully used as an immunosuppressant or a pharmaceutical composition capable of preventing or treating various immune diseases, such as autoimmune diseases, inflammatory diseases, and transplant rejection, caused by the dysregulation of immune responses.

Abstract: The present invention refers to the injectable hyaluronic acid composition which is crosslinked viscoelastic hyaluronic acid gel comprising DNA fractions. More particularly, it refers to the injectable hyaluronic acid composition comprising a hyaluronic acid composition crosslinked in the basic conditions with the degree of crosslinking between 0.1 and 200%, which is mixed with the DNA fractions of 0.1 to 50 wt %. The DNA fractions are selected, for example, from polynucleotide (PN) and polydeoxyribonucleotide (PDRN). The composition used for cosmetic purposes or therapeutic purposes, have improved viscoelastic rheological properties and enzyme resistance.

Abstract: The present invention relates to a biguanide derivative compound capable of effectively preventing and treating immune diseases. The biguanide-based derivative compound according to the present invention inhibits the generation of IL-17 and TNF-?, which are inflammatory cytokines, increases the activity of regulatory T cells having an immunomodulatory function, and exhibits excellent therapeutic effects in animal models of immune diseases. Accordingly, the biguanide-based derivative compound can be usefully used as an immunosuppressant or a pharmaceutical composition capable of preventing or treating various immune diseases, such as autoimmune diseases, inflammatory diseases, and transplant rejection, caused by the dysregulation of immune responses.

Abstract: Disclosed herein is a scribing wheel having a predetermined thickness and a disk shape. The scribing wheel includes: a wheel body configured in such a way that at least a peripheral edge portion thereof is gradually reduced in thickness from the center to the radial outside; and a cutter part including recesses and cutting blade teeth which are alternately arranged along the peripheral edge portion. Each recess is formed by a combination of side recess portions formed in opposite side surfaces of the peripheral edge portion of the wheel body and an edge recess portion formed in the peripheral edge of the wheel body.

Abstract: An electronic device and a power saving method of an electronic device forming an ad-hoc network are provided. The electronic device includes a communication circuit configured to transmit a beacon frame defining a beacon interval to an external device forming an ad-hoc network with the electronic device; and a processor configured to determine a state of the communication circuit during the beacon interval based on whether an announcement traffic indication message (ATIM) frame is transceived between the electronic device and the external electronic device. The method includes receiving power saving mode support information indicating whether to support a power saving mode function, from at least one external device; and activating or deactivating the power saving mode function of the electronic device based on the power saving mode support information.

Abstract: An electronic device may include a network interface, a wireless communication circuit configured to support directional communication, a processor electrically connected with the network interface and the wireless communication circuit, and a memory electrically connected with the processor.

Abstract: Disclosed is a method and system for playing content using a smart signage device. An embodiment of a content playing method using a smart signage device according to the present disclosure may include: checking coupling or separation of a smart signage device; determining a screen group in association with the coupling or separation of the smart signage device; generating content suitable for the screen group; determining mash-up content assigned to at least one smart signage device included in the screen group; and plying the mash-up content assigned to the at least one smart signage device.

Abstract: The present invention relates to a composition for treating osteoarthritis and a method for preparing the same, and more specifically, relates to a composition comprising hydrophilized sulfasalazine as an active ingredient and hyaluronic acid so as to enable effective treatment of osteoarthritis such as degenerative osteoarthritis by preventing joint wear in addition to symptom relief through intraarticular or local administration, and a method for preparing the same.

Abstract: The present invention refers to the injectable hyaluronic acid composition which is crosslinked viscoelastic hyaluronic acid gel comprising DNA fractions. More particularly, it refers to the injectable hyaluronic acid composition comprising a hyaluronic acid composition crosslinked in the basic conditions with the degree of crosslinking between 0.1 and 200%, which is mixed with the DNA fractions of 0.1 to 50 wt %. The DNA fractions are selected, for example, from polynucleotide (PN) and polydeoxyribonucleotide (PDRN). The composition used for cosmetic purposes or therapeutic purposes, have improved viscoelastic rheological properties and enzyme resistance.

Abstract: Provided is a novel compound capable of effectively preventing and treating immune diseases and a use thereof. The novel compound of the present subject matter has effects of inhibiting the production of inflammatory cytokines, increasing the activity of regulatory T cells having immunoregulatory functions, inhibiting the production of auto-antibodies to regulate excessive immune responses, and inhibiting the differentiation of osteoclasts, and thus can be used for treating immune diseases, such as autoimmune disease, inflammatory disease, and transplant rejection diseases, which are caused by abnormal regulation of various kinds of immune response.

Abstract: A bidet apparatus according to an embodiment of the present invention may comprise: a nozzle case provided inside of a frame; a nozzle, provided in the nozzle case so as to be movable forward and backward, having a discharge outlet at one end thereof; and a drier, provided inside of the frame, for spraying air toward the discharge outlet. As such, a user can dry a nozzle discharge cutlet by only a simple button operation.