Abstract: The present invention provides peptides comprising a sequence derived from the human NAF-1 protein, analogs of said sequence or a retro-inverso sequence of said peptide or analog. The conjugates of such peptides are provided as well. The peptides and the conjugates of the present invention are useful in treating cancer, and in particular cancer in which the expression of NAF-1 is enhanced.

Abstract: The present invention relates to a method for preparing a modified conjugated diene-based polymer, and more particularly, provides a method for preparing a modified conjugated diene-based polymer including a step of polymerizing a conjugated diene-based monomer in the presence of an organometal compound in a hydrocarbon solvent to prepare an active polymer which is coupled with an organometal (S1); and a step of reacting or coupling the active polymer prepared in step (S1) with a modifier (S2), wherein step (S1) is continuously performed in two or more polymerization reactors, and a polymerization conversion ratio in a first reactor among the polymerization reactors is 50% or less.

Abstract: A liquid crystal display device including a display area, a non-display area surrounding the display area and including a first non-display area disposed on a first side, in a first direction, of the display area and a second non-display area disposed on a second side, in the first direction, of the display area, a first substrate including a first base and a plurality of spacers that are disposed on a first surface of the first base, a second substrate disposed on the first substrate, and a liquid crystal layer disposed between the first and second substrates. The spacers include first spacers, having a first thickness, disposed in the non-display area and second spacers, having a second thickness greater than the first thickness, disposed in the non-display area. A number of second spacers disposed in a first non-display area is different from a number of second spacers disposed in a second non-display area.

Abstract: The present invention relates to a pharmaceutical composition for forming a film directly on a wound to accelerate wound healing, a use for the same, a treatment method using the same, and a method for preparing the same. The film-forming composition according to the present invention forms a film directly on the wound to increase the adhesion to the wound. The formed thin hydrophilic film protects the wound surface to prevent infection of the wound surface, retains the physiologically active substance useful for wound healing on the wound surface to promote the wound healing, and allow drugs to be continuously delivered to the wound surface. Therefore, the composition according to the present invention has excellent wound healing effect and has excellent usability as it is not absorbed into clothing, bandage, etc., thus effectively replacing conventional gel or ointment formations for delivering physiologically active substances.

Abstract: A liquid crystal display includes a first display substrate, a second display substrate facing the first display substrate, and a liquid crystal layer interposed between the first and second display substrates, where the first display substrate includes a lower substrate, a pixel electrode, which is disposed on the lower substrate, and a protrusion pattern, which is disposed on the pixel electrode along an outer edge of the pixel electrode, the second display substrate includes an upper substrate and a light-shielding member, which is disposed on a surface of the upper substrate facing the first display substrate and in which indentation pattern parts are inwardly indented in a plan view, the light-shielding member includes light-shielding parts that are an entirety of the light-shielding member except for the indentation pattern parts, and the indentation pattern parts overlap parts of the pixel electrode.

Abstract: Disclosed are a modified conjugated diene-based polymer represented by Chemical Formula 2a or 2b defined herein and a method of preparing the same.

Abstract: The present invention relates to a method for producing a modified polymerization initiator, and more particularly, to a method for preparing a modified polymerization initiator, wherein the method includes the steps of: (S1) introducing a first fluid and a second fluid into a reactor, and reacting the compounds included in the fluids, and (S2) obtaining the modified polymerization initiator prepared by the reaction of the step (S1) through an outlet of the reactor, wherein the step (S1) and step (S2) are continuously performed, wherein in the step (S1), the flow amount of the first fluid and the second fluid is maintained constant at the time when the first fluid and the second fluid are mixed, and the flow rate of the first fluid is increased. Also, the present invention provides an apparatus for producing a modified polymerization initiator for performing the same.

Abstract: Disclosed are a modified conjugated diene-based polymer represented by a specific Chemical Formula and a method of preparing the same.

Abstract: The present invention provides a modified conjugated diene-based polymer which includes a functional group derived from a substituted styrene-based compound and a functional group derived from an aminosilane-based compound, a method for preparing the same, and a rubber composition including the same. The modified conjugated diene-based polymer includes the functional group derived from an aminosilane-based compound of Formula 1 and a functional group derived from a substituted styrene-based compound of Formula 2 at both terminals of a main chain, and thus, shows a high modification ratio. When applying the polymer in a rubber composition, excellent affinity with a filler may be shown, and as a result, agglomeration of a filler in the rubber composition may be prevented, and the dispersibility of the filler may be increased, thereby improving the processability of the rubber composition.

Abstract: The present invention relates to a polymer compound used as a polymer modifier, a conjugated diene-based polymer including a functional group derived therefrom, and a method for preparing a modified and conjugated diene-based polymer using the polymer compound. A rubber modifier compound obtained therefrom is used as a modifier for rubber, particularly, as a modifier of a conjugated diene-based polymer and is bonded to a chain of the conjugated diene-based polymer to easily introduce a functional group having affinity with a filler.

Abstract: The present invention relates to a method of preparing a modified conjugated diene-based polymer, and more particularly, to a method of preparing a modified conjugated diene-based polymer, including: (S1) preparing an active polymer with an organic metal bonded thereto by polymerizing a conjugated diene-based monomer in a hydrocarbon solvent in the presence of an organometallic compound; and (S2) mixing the active polymer prepared according to process S1 with a modifier, wherein the mixing of process S2 is performed at a Reynolds number of 20 or less for 1 minute or more, the Reynolds number being maintained within a range of ±5 of a Reynolds number when the modifier is added (wherein the range is between greater than 0 to 20 or less).

Abstract: The present invention relates to a modifier useful for modifying a polymer, a method for preparing a modified and conjugated diene-based polymer using the same, and a modified and conjugated diene-based polymer prepared thereby. In the modified and conjugated diene-based polymer, a hydroxyl group and a silyl group are combined, and the affinity thereof with a silica-based filler may be excellent. Accordingly, a rubber composition including the modified and conjugated diene-based polymer may have excellent processability, and as a result, molded articles (for example, tires) manufactured from the rubber composition may have excellent tensile strength, abrasion resistance, and viscoelasticity properties.

Abstract: A display apparatus includes a display panel comprising a plurality of pixels, each of the pixels comprising a thin film transistor connected to a gate line and a data line and a display element connected to the thin film transistor, a driving voltage generator configured to generate a gate-on voltage and a plurality of gate-off voltages, a timing controller configured to divide an initial driving period into a plurality of setting periods and output a gate-off voltage corresponding to each of the setting periods, and a gate driver circuit configured to generate a gate signal using the gate-on voltage and the gate-off voltage corresponding to a setting period and output the gate signal to the gate line.

Abstract: A liquid crystal display includes a first display substrate, a second display substrate facing the first display substrate, and a liquid crystal layer interposed between the first and second display substrates, where the first display substrate includes a lower substrate, a pixel electrode, which is disposed on the lower substrate, and a protrusion pattern, which is disposed on the pixel electrode along an outer edge of the pixel electrode, the second display substrate includes an upper substrate and a light-shielding member, which is disposed on a surface of the upper substrate facing the first display substrate and in which indentation pattern parts are inwardly indented in a plan view, the light-shielding member includes light-shielding parts that are an entirety of the light-shielding member except for the indentation pattern parts, and the indentation pattern parts overlap parts of the pixel electrode.

Abstract: Disclosed are a modified conjugated diene-based polymer represented by specific Chemical Formula, a method of preparing the same, and a rubber composition including the same.

Abstract: A liquid crystal display includes: first and second substrate opposite to each other; data lines on the first substrate which transmits a first voltage; a voltage transmitting line on the first substrate which transmits a second voltage; and first and second pixel electrodes on the first substrate and spaced apart from each other, where one of the first and second pixel electrodes is applied with the first voltage through the data lines, the other of the first and second pixel electrodes is applied with the second voltage through the voltage transmitting line, each of the first and second pixel electrodes includes a stem and branches electrodes extending from the stem, the branches of the first pixel electrode and the branches of the second pixel electrode are alternately disposed, and the stems of the first and second pixel electrodes overlap at least a portion of the voltage transmitting line.

Abstract: A display device includes a substrate, a gate line connected to a gate driver, a reference voltage line, a data line crossing the gate line and the reference voltage line, a first thin film transistor including a first drain electrode and connected to the gate line and the data line, a second thin film transistor including a second drain electrode, a third thin film transistor connected to the gate line, the reference voltage line, and the second thin film transistor, and a pixel electrode including a first sub-pixel electrode connected to the first thin film transistor and a second sub-pixel electrode connected to the second thin film transistor. The first drain electrode overlaps the reference voltage line, and an area of a region in which the first drain electrode and the reference voltage line overlap each other increases in a direction toward the gate driver.

Abstract: Provided is a thin film transistor array panel. The thin film transistor array panel includes: an insulation substrate including a display area with a plurality of pixels and a peripheral area around the display area; a gate line and a data line positioned in the display area of the insulation substrate; a first driving signal transfer line and a second driving signal transfer line positioned in the peripheral area of the insulation substrate; a first insulating layer positioned on the gate line and the data line; and a first photosensitive film positioned on the first driving signal transfer line and the second driving signal transfer line, in which the first photosensitive film is disposed only in the peripheral area.

Abstract: A liquid crystal display apparatus includes a plurality of pixels having first and second subpixels, a plurality of gate lines connected to the first and second subpixels to transmit gate signals, a plurality of first data lines intersecting the gate lines and connected to the first subpixels to transmit first data voltages, and a plurality of second data lines intersecting the gate lines and connected to the second subpixels to transmit second data voltages. The first and second data voltages have different sizes and are obtained from single image information. Each pixel is divided into a pair of subpixels, and different data voltages are applied to the subpixels through two different data lines, so that it is possible to secure a wide viewing angle and improve side visibility.

Abstract: Disclosed are a modified conjugated diene-based polymer represented by a specific Chemical Formula and a method of preparing the same.