Publication number: 20210393795
Abstract: Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a —S(?O)(?N—)- functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.
Type:
Application
Filed:
January 2, 2020
Publication date:
December 23, 2021
Inventors:
Taekyo Park, Sung Ho Woo, Sunyoung Kim, Suho Park, Jongun Cho, Doohwan Jung, Donghoon SEO, Jaeho Lee, Sangkwang Lee, Sanghyeon Yun, Jihyeon Ha, Hyang Sook Lee, Okku Park, Beomseol Seo, Sena Kim, Minah Seol, Jina Song