Abstract: The present invention relates to a process for the production of an antibacterial compound suitable for use in the treatment of infection with, or disease caused or exacerbated by, Gram-negative bacteria of the order Enterobacterales and/or Gram-negative bacteria of the genus Haemophilus.

Abstract: An example computer system for provisioning data can include: one or more processors; and non-transitory computer-readable storage media encoding instructions which, when executed by the one or more processors, causes the computer system to create: a marketplace programmed to provide a plurality of application programming interfaces (APIs) for available data sources, the APIs being subscribable for client devices; and an authentication engine programmed to control access by the client devices to the APIs in the marketplace.

Abstract: Aspects of the present disclosure provide streamline techniques to alert sales personal/associate of an item in need of replenishment on the sales floor or in the stock room, and provide real-time data indicating units of an item within a retail location. The present disclosure provides a method, system and computer readable medium for inventory management utilizing radio-frequency identification (RFID) technology. The method may include detecting a first signal from an electronic product code (EPC) tag at a first location; generating a value of an inventory count based on the first signal; detecting a second signal from the EPC tag at a second location; updating the value of the inventory count based on the second signal; comparing the updated value to a threshold value, and when the updated value meets the threshold; and sending a notification of a task to a mobile device.

Abstract: An example computer system for data pipeline orchestration configured to manage and coordinate the end-to-end process involved in moving and transforming data from various sources to designated target repositories can include one or more processors; and non-transitory computer-readable storage media encoding instructions which, when executed by the one or more processors, causes the computer system to create: a user interface configured to receive metadata configuration requirements; a parsing module programmed to parse the metadata configuration requirements into one or more constituent components; and a template selection module programmed identify and select appropriate templates from a template repository used to fulfill the one or more constituent components.

Abstract: A method for collecting and pushing data from an industrial robot controller to at least one data consumer operating a consumer server, implementing a consumer data format and communication protocol, the method including the following steps implemented by a control unit of the industrial robot controller: command the data collector to collect data; command the data collector to store the data in a generic data buffer, the data being stored in a generic format; command the protocol and data adaptor to retrieve stored data from the generic data buffer, and to convert the retrieved data generic format into the consumer data format, and to push the converted data to the consumer server according to the consumer communication protocol.

Abstract: The present invention relates to discovery that TBK1 phosphorylates Syntaxin 17 and that phosphorylation of Syntaxin 17 is intimate to control autophagy initiation. The present invention is directed to this discovery and the use of TBK1 inhibitors or inhibitors of Syntaxin 17 phosphorylation alone or in combination with additional bioactive agents to inhibit autophagy in the treatment of disease, especially the treatment of cancers. Methods of treating various cancers are disclosed using TBK1 inhibitors to patients with cancer and into cancerous tissues for the treatment of cancer including the inhibition, amelioration, reduction in metastasis and in recurrence of cancer in remission. Assays and methods for identifying compounds as inhibitors of Syntaxin 17 and as potential therapeutic agents for cancer and autoimmune diseases are also diseased herein.

Abstract: A method for collecting and pushing data from an industrial robot controller to at least one data consumer operating a consumer server, implementing a consumer data format and communication protocol, the method including the following steps implemented by a control unit of the industrial robot controller: command the data collector to collect data; command the data collector to store the data in a generic data buffer, the data being stored in a generic format; command the protocol and data adaptor to retrieve stored data from the generic data buffer, and to convert the retrieved data generic format into the consumer data format, and to push the converted data to the consumer server according to the consumer communication protocol.

Abstract: Aspects of the present disclosure include a method, an apparatus, and computer-readable medium for transmitting, via a RFID device, an allocation request for serial numbers to be associated with a product identifier, receiving a batch of serial numbers from a remote server, selecting a first serial number from the batch of serial numbers, wherein the first serial number is selected during a time period in which the RFID device lacks network connectivity with the remote server, transmitting the first serial number to a first RFID tag configured to be coupled with an article associated with the product identifier, and transmitting an update to the remote server indicating that the first serial number has been registered to the first RFID tag, in response to determining the RFID device is communicatively connected to the remote server.

Abstract: The present invention is directed to elucidating the mechanism of formation of autophagosomal membranes that emerge via convergence of secretory and endosomal pathways and providing therapeutic approaches to the treatment of several acute respiratory syndrome coronavirus 1 (SARS) and 2 SARS-CoV-2), MERS-CoV and numerous other autophagy-mediated diseases based upon this mechanism. This process is targeted by microbial factors such as coronaviral membrane modulating proteins and represents a potential target for agents which may be used in the treatment of SARS, COVID and MERS. The present invention is also directed to compositions and methods for the treatment of SARS, COVID and/or MERS and other autophagy-mediated disease states.

Abstract: A method is provided for manufacturing a nanoparticle material having an ionic conductivity as a battery material for Fluoride ion Batteries, thus, being capable for overcoming high resistances at the surfaces, grain-boundaries of nanoparticles or compartments of the nanoparticles by a material treatment selected from: (i) a ball-mill procedure under aerosol and/or vapour-pressure atmosphere, (ii) excess-synthesis, (iii) ball-milling with surface stabilizing and conductivity enhancing solid or/and gel/liquid additives or (iv) functionalizing the material to obtain functionalized nanoparticles (GSNP) comprising a dispersion of graphene, nanotubes and/or a further additive selected from carbon-black, graphite, Si and/or CFX, Herein, fluorides (EmmFh), fluorides composites (Em1m1Em2m2 . . .

Abstract: A method is provided for manufacturing a nanoparticle material having an ionic conductivity as a battery material for Fluoride ion Batteries, thus, being capable for overcoming high resistances at the surfaces, grain-boundaries of nanoparticles or compartments of the nanoparticles by a material treatment selected from: (i) a ball-mill procedure under aerosol and/or vapour-pressure atmosphere, (ii) excess-synthesis, (iii) ball-milling with surface stabilizing and conductivity enhancing solid or/and gel/liquid additives or (iv) functionalizing the material to obtain functionalized nanoparticles (GSNP) comprising a dispersion of graphene, nanotubes and/or a further additive selected from carbon-black, graphite, Si and/or CFX, Herein, fluorides (EmmFh), fluorides composites (Em1m1Em2m2 . . .

Abstract: Aspects of the present disclosure provide streamline techniques to alert sales personal/associate of an item in need of replenishment on the sales floor or in the stock room, and provide real-time data indicating units of an item within a retail location. The present disclosure provides a method, system and computer readable medium for inventory management utilizing radio-frequency identification (RFID) technology. The method may include detecting a first signal from an electronic product code (EPC) tag at a first location; generating a value of an inventory count based on the first signal; detecting a second signal from the EPC tag at a second location; updating the value of the inventory count based on the second signal; comparing the updated value to a threshold value, and when the updated value meets the threshold; and sending a notification of a task to a mobile device.

Abstract: Aspects of the present disclosure include a method, an apparatus, and computer-readable medium for transmitting, via a RFID device, an allocation request for serial numbers to be associated with a product identifier, receiving a batch of serial numbers from a remote server, selecting a first serial number from the batch of serial numbers, wherein the first serial number is selected during a time period in which the RFID device lacks network connectivity with the remote server, transmitting the first serial number to a first RFID tag configured to be coupled with an article associated with the product identifier, and transmitting an update to the remote server indicating that the first serial number has been registered to the first RFID tag, in response to determining the RFID device is communicatively connected to the remote server.

Abstract: A processing device such as a router or other network device implements a locator-identifier mapping system associating identifiers of respective endpoints with respective locators in accordance with a locator-identifier separation protocol. A first one of the endpoints comprises a storage server associated with a storage array. In conjunction with reconfiguration of the storage server, the locator-identifier mapping system updates a particular one of the locators corresponding to the endpoint identifier of the storage server. The reconfiguration of the storage server may comprise, for example, a migration of the storage server within a given data center, or from a first data center to a second data center. The locator of the storage server illustratively specifies a subnet of the storage server. The processing device may comprise a router operating as at least one of an ingress tunnel router and an egress tunnel router in accordance with the locator-identifier separation protocol.

Abstract: A call is setup between an originating device (A) and a terminating device (B), which both have access to a public land mobile network (131, 132) and a mobile data network (121, 122). The originating and terminating devices device (A; B) include a respective software-implemented call handling tool (SWA; SWB) configured to assist a user in placing and receiving calls. Bridge nodes (140) are connected to the mobile data network (121, 122), the public land mobile network (131, 132) and a server node (110), which also is connected to the mobile data network (121, 122). In response to a call-setup command from a user of the originating device (A), the software-implemented call handling tool (SWA), on one hand, sends a call-setup request (1) to the server node (110); and on the other hand, makes a first call (2) to a first bridge node (140) over the public land mobile network (131) using a first telephone number (#1).

Abstract: Systems and methods for automating an invoice approval process are described herein. Rules are created which are evaluated against a set of attributes. A rules engine is automatically invoked upon receipt of a document in an electronic invoice presentment and payment system. The rules engine determines which rules are applicable to documents received and processed in the system, and applies those applicable rules in a pre-defined sequence.

Abstract: A group call is setup between one originating device (A) and at least two terminating devices (B, C), which each has access to a public land mobile network (131, 132, 133) and a mobile data net-work (121, 122, 123). The originating and terminating devices (A, B, C) include a respective software-implemented call handling tool (SWA, SWB, SWC) configured to assist a user in placing and receiving group calls. Bridge nodes (141, 142, 143) are connected to the mobile data network (121, 122, 123), the public land mobile network (131, 132, 133) and a server node (110), which, in turn, also is connected to the mobile data network (121, 122, 123).

Abstract: A method of temperature control in a cryogenic temperature control apparatus. The method includes operating the cryogenic temperature control apparatus in a first mode, and delivering a first flow rate of cryogen from a storage tank to an evaporator coil in the first mode. The cryogenic temperature control apparatus is operated in a second mode after operating the cryogenic temperature control apparatus in the first mode for a predetermined time duration. A second flow rate of cryogen that is lower than the first flow rate is delivered to the evaporator coil in the second mode.

Abstract: Techniques are described for facilitating access of computing system users to restricted functionality, such as internal functionality of a business or other organization (e.g., internal systems and/or confidential information available to some or all business employees or other organization members). The restricted functionality access may in some situations be provided in conjunction with publicly available information from the organization, such as to use that publicly available information as part of a user interface that allows an authorized subset of users to access the restricted functionality. In some situations, the restricted functionality access may be facilitated by an access provider system that executes on a client computing system of an authorized user, such as a program operating in conjunction with another presentation program that presents publicly available information (e.g.

Abstract: At least one processing device comprises a processor coupled to a memory and implements virtualization infrastructure including a first container comprising a software agent of a locator-identifier separation protocol. The software agent is configured to communicate with a locator-identifier mapping system that associates identifiers of respective endpoints with respective locators in accordance with the locator-identifier separation protocol. The endpoints comprise respective ones of a plurality of additional containers of the virtualization infrastructure. The first container may be coupled to the plurality of additional containers via a bridge element that combines virtual interfaces of respective ones of the additional containers into a single physical network interface.