Patents by Inventor Surya K. Goli

Surya K. Goli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040143111
    Abstract: The present invention provides a human apoptosis-associated protein (HAAP) and polynucleotides which identify and encode HAAP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing HAAP and for treating or preventing disorders associated with expression of HAAP.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 22, 2004
    Applicant: Incyte Corporation
    Inventors: Jennifer L. Hillman, Surya K. Goli, Neil Corley
  • Publication number: 20040063131
    Abstract: The present invention provides polynucleotides which identify and encode two novel human NSP-like proteins (NSPLP). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NSPLP. The invention also provides for the use of substantially purified NSPLP, antagonists, and in pharmaceutical compositions for the treatment of diseases associated with the expression of NSPLP. Additionally, the invention provides for the use of antisense molecules to NSPLP in pharmaceutical compositions for treatment of diseases associated with the expression of NSPLP. The invention also describes diagnostic assays which utilize diagnostic compositions comprising the polynucleotide, fragments or the complement thereof, which hybridize with the genomic sequence or the transcript of polynucleotides encoding NSPLP or anti-NSPLP antibodies which specifically bind to NSPLP.
    Type: Application
    Filed: September 12, 2003
    Publication date: April 1, 2004
    Applicant: Incyte Corporation
    Inventors: Olga Bandman, Janice Au-Young, Surya K. Goli, Jennifer L. Hillman
  • Patent number: 6632617
    Abstract: The invention provides a cDNA which encodes a TUAN. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of inflammatory and cell proliferative disorders, in particular, Crohn's disease and colon cancer. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: October 14, 2003
    Assignee: Incyte Corporation
    Inventors: Olga Bandman, Surya K. Goli, Purvi Shah, Neil C. Corley, David G. Streeter
  • Publication number: 20030170219
    Abstract: The invention provides human disease associated protein kinases and polynucleotides (collectively designated DAPK) which identify and encode them. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing and treating disorders associated with expression of human disease associated protein kinases.
    Type: Application
    Filed: January 24, 2001
    Publication date: September 11, 2003
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Neil C. Corley, Karl J. Guegler, Preeti Lal, Surya K. Goli, Purvi Shah
  • Publication number: 20030171268
    Abstract: The present invention provides a human LEA motif protein (HuLEAP) and polynucleotides which identify and encode HuLEAP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HuLEAP and a method for producing HuLEAP. The invention also provides for agonists, antibodies, or antagonists specifically binding HuLEAP, and their use, in the prevention and treatment of diseases associated with expression of HuLEAP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HuLEAP for the treatment of diseases associated with the expression of HuLEAP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HuLEAP.
    Type: Application
    Filed: June 26, 2001
    Publication date: September 11, 2003
    Applicant: Incyte Genomics, Inc
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Publication number: 20030166231
    Abstract: The present invention provides a human RNA binding protein (HRNABP) and polynucleotides which identify and encode HRNABP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HRNABP and a method for producing HRNABP. The invention also provides for antagonists or antibodies specifically binding HRNABP, and their use, in the prevention and treatment of diseases associated with expression of HRNABP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HRNABP for the treatment of diseases associated with the expression of HRNABP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HRNABP.
    Type: Application
    Filed: May 31, 2002
    Publication date: September 4, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Surya K. Goli
  • Publication number: 20030152989
    Abstract: The present invention provides a novel human integral membrane (IMP-2) and polynucleotides which identify and encode IMP-2. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding IMP-2 and a method for producing IMP-2. The invention also provides for agonists, antibodies, or antagonists specifically binding IMP-2, and their use, in the prevention and treatment of diseases associated with expression of IMP-2. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding IMP-2 for the treatment of diseases associated with the expression of IMP-2. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding IMP-2.
    Type: Application
    Filed: February 11, 2003
    Publication date: August 14, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Publication number: 20030148271
    Abstract: The present invention provides a human prostate-associated kallikrein (HPAK) and polynucleotides which identify and encode HPAK. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPAK and a method for producing HPAK. The invention also provides for antibodies or antagonists specifically binding HPAK, and their use, in the prevention and treatment of diseases associated with expression of HPAK. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HPAK for the treatment of diseases associated with the expression of HPAK. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HPAK.
    Type: Application
    Filed: October 13, 1998
    Publication date: August 7, 2003
    Inventors: JENNIFER L. HILLMAN, SURYA K. GOLI
  • Publication number: 20030147893
    Abstract: The present invention provides a novel human integral membrane (TMP-1) and polynucleotides which identify and encode TMP-1. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding TMP-1 and a method for producing TMP-1. The invention also provides for agonists, antibodies, or antagonists specifically binding TMP-1, and their use, in the prevention and treatment of diseases associated with expression of TMP-1. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding TMP-1 for the treatment of diseases associated with the expression of TMP-1. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding TMP-1.
    Type: Application
    Filed: October 2, 2001
    Publication date: August 7, 2003
    Applicant: Incyte Pharmaceuticals, Inc
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Publication number: 20030143617
    Abstract: The present invention provides two ATP synthase subunits (designated individually as Asy-1 and collectively as Asy) and polynucleotides which identify and encode Asy. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding Asy and a method for producing Asy. The invention also provides for use of Asy and agonists, antibodies, or antagonists specifically binding Asy, in the prevention and treatment of diseases associated with expression of Asy. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding Asy for the treatment of diseases associated with the expression of Asy. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding Asy.
    Type: Application
    Filed: January 21, 2003
    Publication date: July 31, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Surya K. Goli
  • Publication number: 20030109004
    Abstract: The present invention provides a novel human C-type lectin (human PAP-2) and polynucleotides which identify and encode human PAP-2. The invention also provides expression vectors, host cells, agonists, antibodies or antagonists. The invention also provides methods for treating or preventing diseases associated with expression of human PAP-2.
    Type: Application
    Filed: December 10, 2002
    Publication date: June 12, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Publication number: 20030108993
    Abstract: The present invention provides a human mitochondrial chaperone protein (Hmt-GrpE) and polynucleotides which identify and encode Hmt-GrpE. The invention also provides expression vectors and host cells and a method for producing Hmt-GrpE. The invention also provides for antibodies or antagonists specifically binding Hmt-GrpE, and their use in the prevention and treatment of cancer. The invention also provides diagnostic assays. The invention also provides for the use of Hmt-GrpE in identifying antifungal and antiprotozoal therapeutics.
    Type: Application
    Filed: July 30, 2002
    Publication date: June 12, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Surya K. Goli
  • Publication number: 20030099652
    Abstract: The present invention provides a novel protein tyrosine kinase (HPTYK) and polynucleotides which identify and encode HPTYK. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPTYK and a method for producing HPTYK. The invention also provides pharmaceutical compositions containing HPTYK or antagonists to HPTYK, and for the use of these compositions in the treatment of diseases associated with the expression of HPTYK. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HPTYK for the treatment of diseases associated with the expression of HPTYK. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, to hybridize to the genomic sequence or transcripts of polynucleotides encoding HPTYK or antibodies which specifically bind to HPTYK.
    Type: Application
    Filed: February 16, 1999
    Publication date: May 29, 2003
    Inventor: SURYA K. GOLI
  • Publication number: 20030099988
    Abstract: The present invention provides a novel human tumor suppressor (NHTS) and polynucleotides which identify and encode NHTS. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NHTS and a method for producing NHTS. The invention also provides for agonists, antibodies, or antagonists specifically binding NHTS, and their use, in the prevention and treatment of diseases associated with expression of NHTS. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NHTS for the treatment of diseases associated with the expression of NHTS. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NHTS.
    Type: Application
    Filed: September 13, 2002
    Publication date: May 29, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Sam La Brie, Surya K. Goli
  • Publication number: 20030099612
    Abstract: The present invention provides a human microtubule-associated protein (hLC3) and the polynucleotides which identify and encode hLC3. The invention also provides genetically engineered expression vectors, host cells, and a method for producing hLC3. The invention also provides hLC3 as well as agonists, antibodies, and antagonists of hLC3, and the use thereof for the prevention and treatment of diseases associated with the expression of hLC3. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding hLC3 for the treatment of diseases associated with the expression of hLC3. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding hLC3.
    Type: Application
    Filed: July 12, 2001
    Publication date: May 29, 2003
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Publication number: 20030096371
    Abstract: The present invention provides novel human cytokines (designated individually as NHC-1 and NHC-2, and collectively as NHC) and polynucleotides which identify and encode NHC. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NHC and a method for producing NHC. The invention also provides for use of NHC and agonists, antibodies, or antagonists specifically binding NHC, in the prevention and treatment of diseases associated with expression of NHC. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NHC for the treatment of diseases associated with the expression of NHC. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NHC.
    Type: Application
    Filed: November 19, 2002
    Publication date: May 22, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Phillip R. Hawkins, Lynn E. Murry, Surya K. Goli
  • Publication number: 20030088084
    Abstract: The present invention provides three zinc binding proteins (designated individually as ZB-1, ZB-2, and ZB-3, and collectively as ZB) and polynucleotides which identify and encode ZB. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding ZB and a method for producing ZB. The invention also provides for use of ZB and agonists, antibodies, or antagonists specifically binding ZB, in the prevention and treatment of diseases associated with expression of ZB. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding ZB for the treatment of diseases associated with the expression of ZB. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding ZB.
    Type: Application
    Filed: October 9, 2002
    Publication date: May 8, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Janice Au-Young, Roger Coleman, Surya K. Goli
  • Publication number: 20030087391
    Abstract: The present invention provides B cell receptor associated proteins (BCRP) and polynucleotides which identify and encode BCRP. The invention also provides expression vectors, host cells, agonists, antibodies, and antagonists. The invention also provides methods for treating disorders associated with expression of BCRP.
    Type: Application
    Filed: October 25, 2002
    Publication date: May 8, 2003
    Applicant: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Surya K. Goli, Sherry A. Capitant
  • Patent number: 6545129
    Abstract: The present invention provides a human selenoprotein (HSEL) and polynucleotides which identify and encode HSEL. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HSEL and a method for producing HSEL. The invention also provides for agonists, antibodies, or antagonists specifically binding, HSEL, and their use, in the prevention and treatment of diseases associated with expression of HSEL. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HSEL for the treatment of diseases associated with the expression of HSEL. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HSEL.
    Type: Grant
    Filed: September 10, 1999
    Date of Patent: April 8, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Patent number: 6531575
    Abstract: The present invention provides two ATP synthase subunits (designated individually as Asy-1 and Asy-2, and collectively as Asy) and polynucleotides which identify and encode Asy. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding Asy and a method for producing Asy. The invention also provides for use of Asy and agonists, antibodies, or antagonists specifically binding Asy, in the prevention and treatment of diseases associated with expression of Asy. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding Asy for the treatment of diseases associated with the expression of Asy. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding Asy.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: March 11, 2003
    Assignee: Incyte Genomics, Inc.
    Inventors: Olga Bandman, Jennifer L. Hillman, Surya K. Goli