Patents by Inventor Surya K. Goli
Surya K. Goli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20030044401Abstract: The present invention provides a human glutathione s-transferase (HGST) and polynucleotides which identify and encode HGST. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HGST and a method for producing HGST. The invention also provides for agonists, antibodies, or antagonists specifically binding HGST, and their use, in the prevention and treatment of cancer and other diseases associated with the expression of HGST. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HGST for the treatment of cancer and other diseases associated with the expression of HGST. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HGST.Type: ApplicationFiled: February 14, 2001Publication date: March 6, 2003Applicant: Incyte Pharmaceuticals, Inc.Inventors: Surya K. Goli, Jennifer L. Hillman
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Publication number: 20030022332Abstract: The present invention provides a novel human phosphatase inhibitor protein (HPIP) and polynucleotides which identify and encode HPIP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPIP and a method for producing HPIP. The invention also provides for agonists, antibodies, or antagonists specifically binding HPIP, and their use, in the prevention and treatment of diseases associated with expression of HPIP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HPIP for the treatment of diseases associated with the expression of HPIP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HPIP.Type: ApplicationFiled: August 6, 2002Publication date: January 30, 2003Applicant: Incyte Genomics, Inc.Inventors: Olga Bandman, Surya K. Goli
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Publication number: 20030008311Abstract: The present invention provides a human histone-like protein (HLP) and polynucleotides which identify and encode HLP. In addition, the invention provides expression vectors and host cells, agonists, antibodies, and antagonists. The invention also provides methods for producing HTP and for treating disorders associated with the expression of HLP.Type: ApplicationFiled: June 4, 2002Publication date: January 9, 2003Applicant: Incyte Genomics, Inc., formerly known as Incyte Pharmaceuticals, Inc.Inventors: Olga Bandman, Surya K. Goli, Hong Zhang
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Patent number: 6503733Abstract: The present invention provides a novel human anion channel (NANCH) and polynucleotides which identify and encode NANCH. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NANCH and a method for producing NANCH. The invention also provides for agonists, antibodies, or antagonists specifically binding NANCH, and their use, in the prevention and treatment of diseases associated with expression of NANCH. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NANCH for the treatment of diseases associated with the expression of NANCH. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NANCH.Type: GrantFiled: October 16, 2000Date of Patent: January 7, 2003Assignee: Incyte Genomics, Inc.Inventors: Olga Bandman, Surya K. Goli
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Patent number: 6492499Abstract: The present invention provides a novel human C-type lectin (human PAP-2) and polynucleotides which identify and encode human PAP-2. The invention also provides expression vectors, host cells, agonists, antibodies or antagonists. The invention also provides methods for treating or preventing diseases associated with expression of human PAP-2.Type: GrantFiled: January 7, 1999Date of Patent: December 10, 2002Assignee: Incyte Genomics, Inc.Inventors: Jennifer L. Hillman, Surya K. Goli
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Publication number: 20020177699Abstract: The present invention provides a human phosphatidylinositol synthase (PISH) and polynucleotides which identify and encode PISH. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding PISH and a method for producing PISH. The invention also provides for agonists, antibodies, or antagonists specifically binding PISH, and their use, in the prevention and treatment of diseases associated with expression of PISH. The invention also provides for the use of PISH in screening for antiprotozoal and antifungal therapeutics. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding PISH for the treatment of diseases associated with the expression of PISH. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding PISH.Type: ApplicationFiled: April 25, 2002Publication date: November 28, 2002Applicant: Incyte Genomics, Inc.Inventors: Olga Bandman, Surya K. Goli
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Publication number: 20020177700Abstract: The present invention provides a human Ras-like protein (RLP) and polynucleotides which identify and encode RLP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing RLP and for treating or preventing disorders associated with expression of RLP.Type: ApplicationFiled: March 4, 2002Publication date: November 28, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Jennifer L. Hillman, Surya K. Goli, Neil C. Corley
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Patent number: 6485933Abstract: The present invention provides B cell receptor associated proteins (BCRP) and polynucleotides which identify and encode BCRP. The invention also provides expression vectors, host cells, agonists, antibodies, and antagonists. The invention also provides methods for treating disorders associated with expression of BCRP.Type: GrantFiled: May 7, 1997Date of Patent: November 26, 2002Assignee: Incyte Genomics, Inc.Inventors: Olga Bandman, Jennifer L. Hillman, Surya K. Goli, Sherry A. Capitant
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Publication number: 20020173022Abstract: The invention provides a human protein phosphatase (PROPHO) and polynucleotides which identify and encode PROPHO. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PROPHO.Type: ApplicationFiled: February 5, 2002Publication date: November 21, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Olga Bandman, Surya K. Goli, Preeti Lal, Neil C. Corley, Hong Zhang
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Publication number: 20020169308Abstract: The present invention provides a novel human integral membrane (IMP) and polynucleotides which identify and encode IMP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding IMP and a method for producing IMP. The invention also provides for agonists, antibodies, or antagonists specifically binding IMP, and their use, in the prevention and treatment of diseases associated with expression of IMP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding IMP for the treatment of diseases associated with the expression of IMP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding IMP.Type: ApplicationFiled: July 2, 2001Publication date: November 14, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Jennifer L. Hillman, Surya K. Goli
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Publication number: 20020170079Abstract: The present invention provides three human LIM proteins (designated individually as HLIM-1, HLIM-2, and HLIM-3, and collectively as HLIM) and polynucleotides which identify and encode HLIM. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HLIM and a method for producing HLIM. The invention also provides for use of HLIM and agonists, antibodies, or antagonists specifically binding HLIM, in the prevention and treatment of diseases associated with expression of HLIM. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HLIM for the treatment of diseases associated with the expression of HLIM. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HLIM.Type: ApplicationFiled: April 18, 2002Publication date: November 14, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Surya K. Goli, Jennifer L. Hillman, Olga Bandman
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Publication number: 20020160499Abstract: The present invention provides a human serine carboxypeptidase (CPEPT) and polynucleotides which identify and encode CPEPT. The invention also provides expression vectors, host cells, agonists, antibodies, and antagonists. The invention also provides methods for treating disorders associated with expression of CPEPT.Type: ApplicationFiled: February 25, 2002Publication date: October 31, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Olga Bandman, Phillip R. Hawkins, Jennifer L. Hillman, Preeti Lal, Surya K. Goli
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Patent number: 6472508Abstract: The present invention provides a novel human tumor suppressor (NHTS) and polynucleotides which identify and encode NHTS. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NHTS and a method for producing NHTS. The invention also provides for agonists, antibodies, or antagonists specifically binding NHTS, and their use, in the prevention and treatment of diseases associated with expression of NHTS. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NHTS for the treatment of diseases associated with the expression of NHTS. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NHTS.Type: GrantFiled: December 18, 1998Date of Patent: October 29, 2002Assignee: Incyte Genomics, Inc.Inventors: Sam La Brie, Surya K. Goli
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Publication number: 20020156256Abstract: The present invention provides a human H-rev107-like protein (HREVP) and polynucleotides which identify and encode HREVP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HREVP and a method for producing HREVP. The invention also provides for agonists, antibodies, or antagonists specifically binding HREVP, and their use, in the prevention and treatment of diseases associated with expression of HREVP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HREVP for the treatment of diseases associated with the expression of HREVP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HREVP.Type: ApplicationFiled: December 6, 2001Publication date: October 24, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Olga Bandman, Surya K. Goli
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Publication number: 20020155538Abstract: The present invention provides a novel endothelial growth factor (NVR) and polynucleotides which identify and encode NVR. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NVR and a method for producing NVR. The invention also provides for agonists, antibodies, or antagonists specifically binding NVR, and their use, in the prevention and treatment of diseases associated with expression of NVR. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NVR for the treatment of diseases associated with the expression of NVR. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NVR.Type: ApplicationFiled: January 9, 2002Publication date: October 24, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Olga Bandman, Surya K. Goli, Lynn E. Murry
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Publication number: 20020132999Abstract: The present invention provides two human p24 vesicle trafficking proteins (designated individually as Hp24-1 and Hp24-2 and collectively as Hp24) and polynucleotides which identify and encode Hp24. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding Hp24 and a method for producing Hp24. The invention also provides for agonists, antibodies, or antagonists specifically binding Hp24, and their use, in the prevention and treatment of diseases associated with expression of Hp24. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding Hp24 for the treatment of diseases associated with the expression of Hp24. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding Hp24.Type: ApplicationFiled: October 19, 2001Publication date: September 19, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Surya K. Goli, Olga Bandman
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Publication number: 20020127689Abstract: The present invention provides two novel human galectins (designated individually as GAL-5HA and GAL-5HB, and collectively as GAL-5H) and polynucleotides which identify and encode GAL-5H. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding GAL-5H and a method for producing GAL-5H. The invention also provides for use of GAL-5H and agonists, antibodies, or antagonists specifically binding GAL-5H, in the prevention and treatment of diseases associated with expression of GAL-5H. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding GAL-5H for the treatment of diseases associated with the expression of GAL-5H. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding GAL-5H.Type: ApplicationFiled: June 27, 2001Publication date: September 12, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Jennifer L. Hillman, Surya K. Goli, Olga Bandman, Phillip R. Hawkins, Joanne R. Petithory
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Publication number: 20020128463Abstract: The present invention provides a human mitochondrial membrane protein (HuTIM17) and polynucleotides which identify and encode HuTIM17. The invention also provides expression vectors and host cells and a method for producing HuTIM17. The invention also provides for antibodies or antagonists specifically binding HuTIM17, and their use in the prevention and treatment of cancer. The invention also provides diagnostic assays. The invention also provides for the use of HuTIM17 in identifying antifungal and antiprotozoal therapeutics.Type: ApplicationFiled: January 4, 2002Publication date: September 12, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Jennifer L. Hillman, Surya K. Goli
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Publication number: 20020115153Abstract: The present invention provides a human proline-rich acidic protein (PRAP) and polynucleotides which identify and encode PRAP. In addition, the invention provides expression vectors and host cells, agonists, antibodies, or antagonists. This invention also provides methods for preventing or treating disorders associated with the expression of PRAP.Type: ApplicationFiled: February 1, 2002Publication date: August 22, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Preeti Lal, Jennifer L. Hillman, Surya K. Goli
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Patent number: 6436637Abstract: The invention provides a human protein phosphatase (PROPHO) and polynucleotides which identify and encode PROPHO. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PROPHO.Type: GrantFiled: December 7, 1998Date of Patent: August 20, 2002Assignee: Incyte Genomics, Inc.Inventors: Olga Bandman, Surya K. Goli, Preeti Lal, Neil C. Corley, Hong Zhang