Patents by Inventor Susan E. Brophy

Susan E. Brophy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-GP73 monoclonal antibodies and methods of obtaining the same
    Patent number: 11421023
    Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: August 23, 2022
    Assignee: ABBOTT LABORATORIES
    Inventors: Bailin Tu, Robert N. Ziemann, Bryan C. Tieman, Philip M. Hemken, Carol S. Ramsay, Carolyn J. Strobel, David J. Hawksworth, Larry G. Birkenmeyer, Cheng Zhao, Susan E. Brophy, Barry L. Dowell, Anthony S. Muerhoff
  • ANTI-GP73 MONOCLONAL ANTIBODIES AND METHODS OF OBTAINING THE SAME
    Publication number: 20190315844
    Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
    Type: Application
    Filed: April 17, 2019
    Publication date: October 17, 2019
    Inventors: Bailin Tu, Robert N. Ziemann, Bryan C. Tieman, Philip M. Hemken, Carol S. Ramsay, Carolyn J. Strobel, David J. Hawksworth, Larry G. Birkenmeyer, Cheng Zhao, Susan E. Brophy, Barry L. Dowell, Anthony S. Muerhoff
  • Anti-GP73 monoclonal antibodies and methods of obtaining the same
    Patent number: 10308709
    Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: June 4, 2019
    Assignee: Abbott Laboratories
    Inventors: Bailin Tu, Robert N. Ziemann, Bryan C. Tieman, Philip M. Hemken, Carol S. Ramsay, Carolyn J. Strobel, David J. Hawksworth, Larry G. Birkenmeyer, Cheng Zhao, Susan E. Brophy, Barry L. Dowell, Anthony S. Muerhoff
  • ANTI-T. CRUZI ANTIBODIES AND METHODS OF USE
    Publication number: 20190162726
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Application
    Filed: December 31, 2018
    Publication date: May 30, 2019
    Inventors: David J. Hawksworth, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Susan E. Brophy, Dinesh O. Shah, Joan D. Tyner, Robert N. Ziemann
  • Anti-antibodies and methods of use
    Patent number: 10215754
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: February 26, 2019
    Assignee: Abbott Laboratories
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • ANTI-GP73 MONOCLONAL ANTIBODIES AND METHODS OF OBTAINING THE SAME
    Publication number: 20170096477
    Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
    Type: Application
    Filed: October 11, 2016
    Publication date: April 6, 2017
    Inventors: Bailin Tu, Robert N. Ziemann, Bryan C. Tieman, Philip M. Hemken, Carol S. Ramsay, Carolyn J. Strobel, David J. Hawksworth, Larry G. Birkenmeyer, Cheng Zhao, Susan E. Brophy, Barry L. Dowell, Anthony S. Muerhoff
  • ANTI-T. CRUZI ANTIBODIES AND METHODS OF USE
    Publication number: 20170023568
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Application
    Filed: October 6, 2016
    Publication date: January 26, 2017
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • Anti-antibodies and methods of use
    Patent number: 9482667
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: November 1, 2016
    Assignee: ABBOTT LABORATORIES
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • Anti-GP73 monoclonal antibodies and methods of obtaining the same
    Patent number: 9469686
    Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: October 18, 2016
    Assignee: ABBOTT LABORATORIES
    Inventors: Bailin Tu, Robert N. Ziemann, Bryan C. Tieman, Philip M. Hemken, Carol S. Ramsay, Carolyn J. Strobel, David J. Hawksworth, Larry G. Birkenmeyer, Cheng Zhao, Susan E. Brophy, Barry L. Dowell, Anthony S. Muerhoff
  • ANTI-T. CRUZI ANTIBODIES AND METHODS OF USE
    Publication number: 20150212083
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Application
    Filed: April 14, 2015
    Publication date: July 30, 2015
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • Anti-antibodies and methods of use
    Patent number: 9073984
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: July 7, 2015
    Assignee: ABBOTT LABORATORIES
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use
    Patent number: 8993248
    Abstract: Vitamin D binding proteins (DBP), in particular truncated DBP and mutated, truncated DBP, as well as fusion proteins thereof, nucleic acid molecules encoding same, vectors, host cells, and methods, kits and solid supports for determining the total amount of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3 in a test sample.
    Type: Grant
    Filed: December 23, 2012
    Date of Patent: March 31, 2015
    Assignee: Abbott Laboratories
    Inventors: Christian Beckert, Susan E. Brophy, Jonathan Grote, Dagang Huang, Jan Schultess, Bailin Tu
  • ANTIBODIES TO TROPONIN I AND METHODS OF USE THEREOF
    Publication number: 20150024457
    Abstract: The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
    Type: Application
    Filed: September 5, 2014
    Publication date: January 22, 2015
    Inventors: Susan E. Brophy, Bailin Tu, Joan D. Tyner, Dagang Huang, Robert N. Ziemann
  • PlGF-1 assay and kits and components thereof
    Patent number: 8741287
    Abstract: The present disclosure relates to glycosylated and deglycosylated human PlGF-1, methods of using the glycosylated and deglycosylated human PlGF-1, antibodies that bind to human PlGF-1, methods of using the antibodies and human PlGF-1 immunoassays and kits.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: June 3, 2014
    Assignee: Abbott Laboratories
    Inventors: Susan E. Brophy, Lianli Chi, Saul A Datwyler, David J. Hawksworth, Don M. Laird, Sharmila Manoj, Mary S. Pinkus, Dominick L. Pucci, Carol S. Ramsay, David C. Sogin, Bailin Tu, Zhiguang Yu, Robert N. Ziemann, Lowell J. Tyner
  • Dual Variable Domain Immunoglobulins and Uses Thereof
    Publication number: 20140134171
    Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
    Type: Application
    Filed: October 17, 2013
    Publication date: May 15, 2014
    Applicant: ABBVIE INC.
    Inventors: Tariq Ghayur, Junjian Liu, Sharmila Manoj, Susan E. Brophy
  • Dual variable domain immunoglobulins and uses thereof
    Patent number: 8586714
    Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: November 19, 2013
    Assignee: ABBVIE, Inc.
    Inventors: Tariq Ghayur, Junjian Liu, Sharmila Manoj, Susan E. Brophy
  • TRUNCATED HUMAN VITAMIN D BINDING PROTEIN AND MUTATION AND FUSION THEREOF AND RELATED MATERIALS AND METHODS OF USE
    Publication number: 20130295593
    Abstract: Vitamin D binding proteins (DBP), in particular truncated DBP and mutated, truncated DBP, as well as fusion proteins thereof, nucleic acid molecules encoding same, vectors, host cells, and methods, kits and solid supports for determining the total amount of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3 in a test sample.
    Type: Application
    Filed: December 23, 2012
    Publication date: November 7, 2013
    Inventors: Christian Beckert, Susan E. Brophy, Jonathan Grote, Dagang Huang, Jan Schultess, Bailin Tu
  • Soluble FMS-like tyrosine kinase-1 (sFLT-1) antibody and related composition, kit, methods of using, and materials and method for making
    Patent number: 8349325
    Abstract: An isolated antibody that specifically binds to sFlt-1 or a fragment thereof having (i) a variable heavy domain region comprising the amino acid sequence of SEQ ID NO: 2, (ii) a variable light domain region comprising the amino acid sequence of SEQ ID NO: 4, or (iii) both (i) and (ii), a pharmaceutical composition and a kit comprising such an antibody, a method of making such an antibody, a method of determining the presence, amount or concentration of sFlt-1 or a fragment thereof in a test sample, a method of treating a patient in therapeutic or prophylactic need of an antagonist of sFlt-1, an isolated nucleic acid comprising a nucleotide sequence encoding the amino acid sequence of (i) SEQ ID NO: 2, (ii) SEQ ID NO: 4, or (iii) both (i) and (ii), optionally as part of a vector, and a host cell comprising and expressing such a nucleic acid.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: January 8, 2013
    Assignee: Abbott Laboratories
    Inventors: Susan E. Brophy, Saul A. Datwyler, David J. Hawksworth, Don C. Laird, Sharmila Manoj, Dominick L. Pucci, Bryan C. Tieman, Joan Tyner, Lowell J. Tyner, legal representative, Zhiguang Yu
  • ANTI-T. CRUZI ANTIBODIES AND METHODS OF USE
    Publication number: 20120122125
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Application
    Filed: January 19, 2012
    Publication date: May 17, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • Antibodies to troponin I and methods of use thereof
    Patent number: RE45763
    Abstract: The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: October 20, 2015
    Assignee: Abbott Laboratories
    Inventors: Susan E. Brophy, Bailin Tu, Dagang Huang, Lowell J. Tyner, Robert N. Ziemann