Patents by Inventor Suso Jesus PLATERO

Suso Jesus PLATERO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FGFR/PD-1 COMBINATION THERAPY FOR THE TREATMENT OF CANCER
    Publication number: 20230030983
    Abstract: Provided herein are combination therapies for the treatment of cancer. In particular, the disclosed methods are directed to treatment of cancer in a patient comprising administering an antibody that blocks the interaction between PD-1 and PD-L1 and an FGFR inhibitor, wherein the antibody that blocks the interaction between PD-1 and PD-L1 and the FGFR inhibitor are administered if one or more FGFR variants are present in a biological sample from the patient.
    Type: Application
    Filed: March 18, 2022
    Publication date: February 2, 2023
    Applicant: ASTEX THERAPEUTICS LTD
    Inventors: Jayaprakash KARKERA, Suso Jesus PLATERO, Raluca VERONA, Matthew V. LORENZI
  • Use Of FGFR Mutant Gene Panels In Identifying Cancer Patients That Will Be Responsive To Treatment With An FGFR Inhibitor
    Publication number: 20200208224
    Abstract: Disclosed herein are methods of identifying a cancer patient that will be responsive to treatment with a fibroblast growth factor receptor (FGFR) inhibitor and methods of treating cancer patients. The methods involve evaluating a biological sample from the patient for the presence of one or more FGFR mutants from a FGFR mutant gene panel. Kits and primers for identifying the presence of one or more FGFR mutant genes in a biological sample are also disclosed herein.
    Type: Application
    Filed: December 20, 2019
    Publication date: July 2, 2020
    Inventors: Suso Jesus Platero, Jayaprakash Karkera
  • FGFR/PD-1 COMBINATION THERAPY FOR THE TREATMENT OF CANCER
    Publication number: 20200108141
    Abstract: Provided herein are combination therapies for the treatment of cancer. In particular, the disclosed methods are directed to treatment of cancer in a patient comprising administering an antibody that blocks the interaction between PD-1 and PD-L1 and an FGFR inhibitor, wherein the antibody that blocks the interaction between PD-1 and PD-L1 and the FGFR inhibitor are administered if one or more FGFR variants are present in a biological sample from the patient.
    Type: Application
    Filed: October 23, 2019
    Publication date: April 9, 2020
    Applicant: ASTEX THERAPEUTICS LTD
    Inventors: Jayaprakash KARKERA, Suso Jesus PLATERO, Raluca VERONA, Matthew V. LORENZI
  • FGFR/PD-1 combination therapy for the treatment of cancer
    Patent number: 10478494
    Abstract: Provided herein are combination therapies for the treatment of cancer. In particular, the disclosed methods are directed to treatment of cancer in a patient comprising administering an antibody that blocks the interaction between PD-1 and PD-L1 and an FGFR inhibitor, wherein the antibody that blocks the interaction between PD-1 and PD-L1 and the FGFR inhibitor are administered if one or more FGFR variants are present in a biological sample from the patient.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: November 19, 2019
    Assignee: ASTEX THERAPEUTICS LTD
    Inventors: Jayaprakash Karkera, Suso Jesus Platero, Raluca Verona, Matthew V. Lorenzi
  • Use Of FGFR Mutant Gene Panels In Identifying Cancer Patients That Will Be Responsive To Treatment With An FGFR Inhibitor
    Publication number: 20190078166
    Abstract: Disclosed herein are methods of identifying a cancer patient that will be responsive to treatment with a fibroblast growth factor receptor (FGFR) inhibitor and methods of treating cancer patients. The methods involve evaluating a biological sample from the patient for the presence of one or more FGFR mutants from a FGFR mutant gene panel. Kits and primers for identifying the presence of one or more FGFR mutant genes in a biological sample are also disclosed herein.
    Type: Application
    Filed: September 19, 2018
    Publication date: March 14, 2019
    Inventors: Suso Jesus Platero, Jayaprakash Karkera
  • FGFR/PD-1 COMBINATION THERAPY FOR THE TREATMENT OF CANCER
    Publication number: 20160287699
    Abstract: Provided herein are combination therapies for the treatment of cancer. In particular, the disclosed methods are directed to treatment of cancer in a patient comprising administering an antibody that blocks the interaction between PD-1 and PD-L1 and an FGFR inhibitor, wherein the antibody that blocks the interaction between PD-1 and PD-L1 and the FGFR inhibitor are administered if one or more FGFR variants are present in a biological sample from the patient.
    Type: Application
    Filed: March 24, 2016
    Publication date: October 6, 2016
    Inventors: Jayaprakash KARKERA, Suso Jesus Platero, Raluca Verona, Matthew V. Lorenzi
  • USE OF FGFR MUTANT GENE PANELS IN IDENTIFYING CANCER PATIENTS THAT WILL BE RESPONSIVE TO TREATMENT WITH AN FGFR INHIBITOR
    Publication number: 20160090633
    Abstract: Disclosed herein are methods of identifying a cancer patient that will be responsive to treatment with a fibroblast growth factor receptor (FGFR) inhibitor and methods of treating cancer patients. The methods involve evaluating a biological sample from the patient for the presence of one or more FGFR mutants from a FGFR mutant gene panel. Kits and primers for identifying the presence of one or more FGFR mutant genes in a biological sample are also disclosed herein.
    Type: Application
    Filed: September 18, 2015
    Publication date: March 31, 2016
    Inventors: Suso Jesus PLATERO, Jayaprakash Karkera