Abstract: The present application relates to methods of producing exosomes. The application also provides a method for preparing a protein composition comprising culturing an exosome-producing cell expressing a Nef-fusion protein comprising a Nef-derived peptide fused to a protein of interest; isolating exosomes from the exosome-producing cell culture; and purifying the protein of interest from the isolated exosomes. The application further discloses compositions that comprise exosomes containing the Nef-fusion protein, as well as methods of using the Nef-fusion protein and exosomes containing the Nef-fusion protein.

Abstract: An information switch comprises a plurality of input circuits and a plurality of output circuits, the information switch being configured to communicate information units between the input circuits and the output circuits in successive transmission cycles; each input circuit being configured, in dependence upon a queue of one or more information units for transmission via that input circuit and in dependence upon hint data received in respect of a current transmission cycle, to send an information unit transmission request to one or more of the output circuits; and each output circuit being configured, in response to one or more information unit transmission requests received from respective input circuits, to select an input circuit for information unit transmission to that output circuit in a current transmission cycle and to provide hint data indicating a provisional selection, by that output circuit, of an input circuit at a next transmission cycle.

Abstract: In some embodiments, a system for producing liquid fuel from landfill gas includes a tri-reformer that receives landfill gas and produces synthesis gas having a H2:CO ratio of approximately 2:1, and a Fischer-Tropsch synthesis (FTS) reformer that receives the synthesis gas from the tri-reformer and produces liquid fuel.

Abstract: A vehicle system for a vehicle can include sensors and a controller. The sensors can detect a position and speed of the vehicle and a position and speed of an object adjacent to the vehicle's lane. The controller can determine an operational state based on input from the sensors. The controller can operate the vehicle in an autonomous mode, wherein the controller controls the speed of the vehicle and a spacing between the vehicle and the object. The controller can switch from the autonomous mode to a learning mode in response to a driver taking control of the vehicle's speed or steering. In the learning mode, the controller can learn a preferred spacing between the vehicle and the object and a preferred speed relative to the object. The controller can control the vehicle in the autonomous mode based on the preferred spacing and speed during similar operational states.

Abstract: The present application relates to methods of producing exosomes. The application also provides a method for preparing a protein composition comprising culturing an exosome-producing cell expressing a Nef-fusion protein comprising a Nef-derived peptide fused to a protein of interest; isolating exosomes from the exosome-producing cell culture; and purifying the protein of interest from the isolated exosomes. The application further discloses compositions that comprise exosomes containing the Nef-fusion protein, as well as methods of using the Nef-fusion protein and exosomes containing the Nef-fusion protein.

Abstract: A method of treating a subterranean formation, the method including placing a well treatment fluid comprised of at least an enzyme and a breaker additive in the subterranean formation. Initially, the pH of the well treatment fluid is about 11.5. The breaker additive reduces the pH of the well treatment fluid by at least 1.5 to increase the activity of enzyme and accelerate hydrolysis of a crosslinkable component.

Abstract: A composition for treating a subterranean formation is formed from water, a water-soluble polymer and a crosslinking system. The crosslinking system utilizes 1) primary crosslinking agent of at least one of a dialdehyde benzene source, a dioxane, and a trioxane, 2) a secondary low temperature organic crosslinking agent that generates aldehyde, and 3) a phenol source. The crosslinking system provides the composition a delayed gel time of about 2 to about 20 hours at temperatures of about 250° F. (121° C.) or higher. A method of treating a subterranean formation penetrated by a wellbore is also accomplished by forming a treatment fluid from the composition and introducing the treatment fluid into the formation through the wellbore.

Abstract: In some embodiments, a system for producing liquid fuel from landfill gas includes a tri-reformer that receives landfill gas and produces synthesis gas having a H2:CO ratio of approximately 2:1, and a Fischer-Tropsch synthesis (FTS) reformer that receives the synthesis gas from the tri-reformer and produces liquid fuel.

Abstract: The present application relates to methods of producing exosomes. The application also provides a method for preparing a protein composition comprising culturing an exosome-producing cell expressing a Nef-fusion protein comprising a Nef-derived peptide fused to a protein of interest; isolating exosomes from the exosome-producing cell culture; and purifying the protein of interest from the isolated exosomes. The application further discloses compositions that comprise exosomes containing the Nef-fusion protein, as well as methods of using the Nef-fusion protein and exosomes containing the Nef-fusion protein.

Abstract: A method of treating a producing well that includes the introduction of a treatment fluid to the producing well from a surface above the subterranean formation, the treatment fluid comprised of at least PPG particles to enhance the oil rate and reduce the water rate of the producing well.

Abstract: The present application discloses a method for treating microbial infection using an antimicrobial composition comprises antimicrobial peptide which contains at least one VGFPV motif.

Abstract: Embodiments are described for methods and systems for mapping virtual memory pages to physical memory pages by analyzing a sequence of memory-bound accesses to the virtual memory pages, determining a degree of contiguity between the accessed virtual memory pages, and mapping sets of the accessed virtual memory pages to respective single physical memory pages. Embodiments are also described for a method for increasing locality of memory accesses to DRAM in virtual memory systems by analyzing a pattern of virtual memory accesses to identify contiguity of accessed virtual memory pages, predicting contiguity of the accessed virtual memory pages based on the pattern, and mapping the identified and predicted contiguous virtual memory pages to respective single physical memory pages.

Abstract: A vehicle system for a vehicle can include sensors and a controller. The sensors can detect a position and speed of the vehicle and a position and speed of an object adjacent to the vehicle's lane. The controller can determine an operational state based on input from the sensors. The controller can operate the vehicle in an autonomous mode, wherein the controller controls the speed of the vehicle and a spacing between the vehicle and the object. The controller can switch from the autonomous mode to a learning mode in response to a driver taking control of the vehicle's speed or steering. In the learning mode, the controller can learn a preferred spacing between the vehicle and the object and a preferred speed relative to the object. The controller can control the vehicle in the autonomous mode based on the preferred spacing and speed during similar operational states.

Abstract: A network management system manages a virtual network includes an interface system communicatively coupled to one or more servers, a director engine, and a configuration engine. The one or more servers implement a virtual network including one or more virtual machines and one or more containers organized into one or more virtual domains. The interface system generates a graphical user interface displaying graphical representations of the one or more virtual machines and the one or more containers and of the one or more servers; and information associated with the virtual network. The director engine receives a user selection of at least one server, virtual machine, container, or virtual domain, accesses information associated with the user selection, and identifies one or more of servers, virtual machines, containers, and virtual domains associated with the user selection.

Abstract: A method for displaying route information to a driver of a vehicle. The method includes comparing map data and a physical environment in which the vehicle is traveling, identifying differences between the map data and the physical environment in which the vehicle is traveling, and notifying the driver of the differences between the map data and the physical environment.

Abstract: The present application discloses a method for treating microbial infection using an antimicrobial composition comprises antimicrobial peptide which contains at least one VGFPV motif.

Abstract: To efficiently transfer of data from a cache to a memory, it is desirable that more data corresponding to the same page in the memory be loaded in a line buffer. Writing data to a memory page that is not currently loaded in a row buffer requires closing an old page and opening a new page. Both operations consume energy and clock cycles and potentially delay more critical memory read requests. Hence it is desirable to have more than one write going to the same DRAM page to amortize the cost of opening and closing DRAM pages. A desirable approach is batch write backs to the same DRAM page by retaining modified blocks in the cache until a sufficient number of modified blocks belonging to the same memory page are ready for write backs.

Abstract: Ice melting compositions, methods for manufacturing ice melting compositions, and methods for melting ice are disclosed. The ice melting compositions can include a coarse deicing particle nucleus and a fine deicing particle coating substantially surrounding the coarse deicing particle nucleus. The fine particle coating can be attached or bonded to the coarse particle nucleus with a binder. The coarse particle nucleus and the fine particle coating can have a variety of particle sizes.

Abstract: A system for autonomous camera control includes a first robot having a surgical tool mounted as an end effector and a second robot having a camera mounted as an end effector. A controller may be provided for manipulating the second robot, where the controller stores a first kinematic model for the first robot and a second kinematic model for the second robot. The controller may be configured to automatically manipulate the second robot to position the camera based on the second kinematic model and an expected position of the surgical tool according the first kinematic model of the first robot. The controller is further configured to identify a threshold angle from a viewing axis of the camera, calculate a tool angle from the viewing axis of the camera, and move the camera toward or further away from the tool depending on if the tool angle is greater than or less than the threshold angle.

Abstract: In one form, a data processing system includes volatile and non-volatile memory, a central processing unit, and at least one peripheral device. The central processing unit executes a selected one of a plurality of software applications as directed by an operating system by transferring the selected software application from the non-volatile memory to the volatile memory and executing instructions associated with the selected software application from the volatile memory. The at least one peripheral device includes a real-time clock for defining execution contexts for the plurality of software applications. The data processing system further includes a usage pattern analyzer adapted to store history information associated with an execution context for each of the plurality of software applications, and to use the history information to direct the operating system to take at least one action based on the history information.