Abstract: The present invention provides bistramide analogs useful for treating various types of cancer.

Abstract: The present invention describes a laminar flow bioreactor with improved laminar flow lines of fluids. The bioreactor housing defines a chamber adapted to receive a scaffold. An inlet aperture at one end of the chamber is in fluid communication with an outlet aperture at the opposite end of the chamber. A bypass mechanism selectively operable from an open position to a closed position consisting of an iris assembly directs a portion of fluid flowing through the chamber around the scaffold-receiving area. This bioreactor is inserted in a bioreactor system.

Abstract: A unique laparoscopy instrument tip and method which allows simultaneous gasping, cauterization, dissection, containment, enclosure and removal of body tissue. Mechanisms for grasping, holding, manipulating, cauterizing, dissecting, encasement in an enclosed cavity and removing the tissue are provided in one implement allowing easy, safe and quick performance of the procedure.

Abstract: The invention relates to an Apparatus for the growth of artificial organic items, particularly human or animal skin. The growth of skin is possible if a slowly stretched piece of skin or skin substitute is in contact with the nutrient fluid only on its inner side, and in contact with a gas, especially with air, on its outer side.

Abstract: The invention relates to a Microchip for the detection of poor sources of electrical and/or magnetic fields. To detect such poor electrical sources hidden in a body is a difficult problem for which was found a solution by this invention. The invention solves this problem by a Microchip consisting of a plate with parallel rows of recesses, in each recess is a cristall with a magnetic activity, between the rows are one or more wires connected with a voltage source and one or more wires connected with a voltmeter, the whole surface of the plate with the cristals in the recesses and the wires is embeded in a layer of semiconducting polimeres.

Abstract: The present invention provides a novel bistramide analog useful for treating various types of cancer.

Abstract: The present invention relates to methods and devices for cutting produce, such as onions and other vegetables. More particularly, the present invention relates to methods and devices for minimizing exposure to noxious and irritating gasses that are emitted from certain freshly cut produce, such as the syn-propanethial-S-oxide gas that is emitted by freshly cut onions. In certain preferred embodiments of the invention, a device is provided for cutting onions, which comprises (i) an open-ended container that is adapted to hold a liquid and (ii) a slicer that is capable of cutting onions when submerged in the liquid that is housed within the container.

Abstract: A radioimmunoconjugate for targeted alpha therapy comprises an alpha-emitter (e.g. Bi-213) linked to the monoclonal antibody C595. This radioimmunoconjugate is widely applicable in cancer therapy and is particularly efficient for treatment of pancreatic and prostate cancer, as well as for breast and ovarian cancer.

Abstract: The present invention generally relates to certain novel methods of chopping onions, while avoiding (or reducing) exposure to syn-propanethial-S-oxide gas emitted from such onions. In certain embodiments, the methods generally comprise placing an onion on a cutting platform, applying heat to the cutting platform or the air surrounding the cutting platform, and applying a vacuum pressure to the air surrounding the cutting platform. In certain specific embodiments, the methods generally comprise (a) placing a cutting platform sufficiently near a heat source and ventilation hood such that air directly above the cutting platform increases in temperature and exhibits a vacuum force towards the ventilation hood when the heat source and ventilation hood are activated, (b) activating the heat source and ventilation hood, and (c) cutting the onion on the cutting platform.

Abstract: The field of the present invention relates to medical devices. More particularly, the field of the present invention relates to devices for providing anesthesia to an endometrial cavity of a patient and, furthermore, to methods of using such devices for endometrial biopsy and other medical procedures. According to certain preferred embodiments of the invention, devices for delivering anesthesia to an endometrial cavity are provided, which generally comprise (i) a primary shaft, (ii) a port located in a backside portion of the device, and (iii) a substantially spherical tip.

Abstract: A Laminar Flow reactor for large scale culturing or packaging of cell suspensions, three-dimensional tissue and other biological systems is disclosed. The Laminar Flow reactor consists of an upper housing and a lower housing. The housings are interconnected by a plurality of connectors and a plurality of rigid spacers, an inlet fluid, an outlet fluid, a fluid reservoir, and a means for transporting fluid within the system. During treatment, liquid media is transported from the fluid reservoir to the inlet manifold, which will in turn evenly distribute the media to each of the connected connectors and internal culture pockets. Laminar flow through the device is maintained by the cylindrical shape of the device and by bypasses. An outlet fluid manifold is also provided to ensure that each treatment chamber is evenly filled and to ensure that any air bubbles formed during treatment are removed from the treatment chambers.

Abstract: The present invention relates to methods and devices for cutting produce, such as onions and other vegetables. More particularly, the present invention relates to methods and devices for minimizing exposure to noxious and irritating gasses that are emitted from certain freshly cut produce, such as the syn-propanethial-S-oxide gas that is emitted by freshly cut onions. In certain preferred embodiments of the invention, a device is provided for cutting onions, which comprises (i) an open-ended container that is adapted to hold a liquid and (ii) a slicer that is capable of cutting onions when submerged in the liquid that is housed within the container.

Abstract: The inventions relate to a method for producing a microchip that is able to detect infrared light with a semiconductor, the basic infrared light is absorber by the semiconductor surrounded, attached or embedded in a polymer which is brought in a thin layer on the surface of the semiconductor and which is grown by polymer around the semiconductor in an acid fluid.

Abstract: The present invention relates to professional scales. A hook for professional scales is provided. Hook allows the user of professional scale to hold the personal items while using the scale.

Abstract: The present invention relates to postpartum uterine manipulators and methods of use thereof. According to certain embodiments of the invention, the devices generally comprise (a) a primary shaft having a proximal end and a distal end, and which encapsulates an interior shaft; (b) a handle located at the proximal end of the primary shaft, which comprises a ratchet, two fixed rings and a movable thumb piece coupled to the interior shaft; and (c) a tip located at the distal end of the primary shaft, which comprises multiple sections connected by joints that forms a triangular configuration when in an open position.

Abstract: A unique laparoscopy instrument tip and method which allows simultaneous gasping, cauterization, dissection, containment, enclosure and removal of body tissue. Mechanisms for grasping, holding, manipulating, cauterizing, dissecting, encasement in an enclosed cavity and removing the tissue are provided in one implement allowing easy, safe and quick performance of the procedure.

Abstract: The present invention relates to devices and methods that are used by a parturient during labor. More particularly, the present invention relates to devices and methods for preventing and managing shoulder dystocia. The present invention further relates to devices and methods for assisting a parturient with laboring efforts.

Abstract: The present invention relates generally to sulfated micelle compositions, methods of manufacture, and applications thereof. In particular, the micelles of the present invention provide an efficient enantiomeric separation and detection techniques for use in capillary electrophoresis and capillary electrophoresis with mass spectrometry.

Abstract: A radioimmunoconjugate for targeted alpha therapy comprises an alpha-emitter (e.g. Bi-213) linked to the monoclonal antibody C595. This radioimmunoconjugate is widely applicable in cancer therapy and is particularly efficient for treatment of pancreatic and prostate cancer, as well as for breast and ovarian cancer.