Patents by Inventor Sylvain Rault

Sylvain Rault has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6071945
    Abstract: A compound selected from those of formula (I): ##STR1## wherein: R.sub.1 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino,R.sub.2 represents optionally substituted aryl or heteroaryl,R.sub.3 represents hydrogen, halogen, alkyl, nitro, hydroxy, alkoxy, trihaloalkyl, trihaloalkoxy or optionally substituted amino,their isomers and addition pharmaceutically-acceptable acid or base salts thereof and medicinal products containing the same are useful in the treatment of cancer.
    Type: Grant
    Filed: July 26, 1999
    Date of Patent: June 6, 2000
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Cecile Enguehard, Jean-Charles Lancelot, Max Robba, Ghanem Atassi, Alain Pierre, Daniel-Henri Caignard, Pierre Renard
  • Patent number: 5627203
    Abstract: The present invention relates to compounds of formula (I): ##STR1## wherein A, x, y, R.sub.1, R.sub.2 and R.sub.3 are as defined in the description. The compounds are useful for treating diseases requiring a selective serotonin reuptake site and 5-HT.sub.2c or 5-HT.sub.3 ligand.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: May 6, 1997
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Max Robba, Jean-Charles Lancelot, Herv e Prunier, Pierre Renard, Bruno Pfeiffer, B eatrice Guardiola-Lemaitre, Marie-Claire Rettori
  • Patent number: 5599812
    Abstract: The present invention relates to a compound selected from these of formula (I): ##STR1## in which A and R.sub.1 are as defined in the description, and medicinal product containing the same which is useful for treating a disorder linked to the 5-HT.sub.3 receptors.
    Type: Grant
    Filed: April 29, 1994
    Date of Patent: February 4, 1997
    Assignee: Adir Et Compagnie
    Inventors: Sylvain Rault, Jean-Charles Lancelot, Herv e Prunier, Max Robba, Philippe Delagrange, Pierre Renard, G erard Adam
  • Patent number: 5332735
    Abstract: Compounds of the general formula (I): ##STR1## where A, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are defined in the description.Medicinal products.
    Type: Grant
    Filed: November 14, 1991
    Date of Patent: July 26, 1994
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Marie P. Foloppe, Max Robba, Michel Boulouard, Pierre Renard, Michelle Devissaguet, Gerard Adam
  • Patent number: 5190939
    Abstract: The invention relates to compounds of general formula I: ##STR1## in which: R.sub.1 represents a radical of general formula (Z.sub.0), (Z.sub.1), (Z.sub.2), (Z.sub.3) or (Z.sub.4) ##STR2## R.sub.2 represents a methylene radical, a hydroxymethylene radical, a carbonyl radical or a radical of general formula (Y.sub.1), (Y.sub.2), (Y.sub.3) or (Y.sub.4): ##STR3## or, with R.sub.12 and the nitrogen atom to which they are attached, forms a radical of general formula (W): ##STR4## R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10, R.sub.11, R.sub.12 and n being as defined in the description, medicinal products containing the same and a method-of-treating metabolic ailments therewith.
    Type: Grant
    Filed: March 7, 1991
    Date of Patent: March 2, 1993
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Michel Boulouard, Patrick Dallemagne, Max Robba, Beatrice Guardiola, Michelle Devissaguet
  • Patent number: 5153190
    Abstract: The invention relates to pyrrolo [1,2-a] thieno [3,2-f][1,4]diazepine compounds of the formula (I) ##STR1## in which: R.sub.1 is hydrogen; alkyl optionally substituted with alkoxy, hydroxy, cycloalkyl, or phenyl; or alkyl- or arylsulfonyl; R.sub.2 is hydrogen, phenyl, or phenylalkyl; alkyl optionally substituted with hydroxyl, alkoxy, oxo, cycloalkyl or phenyl; or optionally substituted amino; R.sub.3 represents hydrogen or alkyl, and R.sub.4 and R.sub.5 independently represent: hydrogen, alkyl optionally substituted with alkoxy, cycloalkyl, or phenyl; or phenyl; their isomers, diastereoisomers and enantiomers as well as their addition salts with pharmaceutically-acceptable acids. The compounds are useful for treating cerebral ischemia, hypertriglyceridemia, hypercholesterolemia, hyperlipidemia, and hyperglycemia and are obtained in a few steps from the corresponding substituted 2-(1-pyrrolyl)thiophenes ##STR2## Y=--CHO or H; X= CN, CONH.sub.2, CH.sub.2 NHCOR.sub.2, or CH.sub.2 NH.sub.2.
    Type: Grant
    Filed: March 7, 1991
    Date of Patent: October 6, 1992
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Michel Boulouard, Marie P. Foloppe, Max Robba, Beatrice Guardiola, Michelle Devissague
  • Patent number: 5130301
    Abstract: Novel 4H-pyrrolo[1,2-a]thieno[2,3-f][1,4]diazepine which are usable as a medicinal product and correspond to the general formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3 and R.sub.4 have the same meaning as given in the specification.These compounds, as well as their physiologically tolerable salts, may be used in therapy, in particular in the treatment of disorders linked to hypoxemia and to certain metabolic disorders.
    Type: Grant
    Filed: March 26, 1991
    Date of Patent: July 14, 1992
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Michel Boulouard, Max Robba, Beatrice Guardiola, Michelle Devissaguet