Abstract: An organ preservation container includes a container body, joints, and tubes. The container body includes a bottom plate and a side wall. The side wall has through holes. Each joint has a through hole. The tubes are connected to the joints from the inner side of the container body. Thus, the tubes are arranged in advance in the container body in an organ transplant operation. This enables a small number of people to speedily conduct the work of placing an organ removed from the donor in the container body and connecting the tubes to blood vessels in the organ.

Abstract: An anastomosis assist tool comprises a body unit extending in a predetermined advancing direction, and an insertion unit arranged at the tip of the body unit. The body unit includes an anastomosis assist part having an approximately constant cross-sectional shape in a plane perpendicular to the advancing direction. The anastomosis assist part includes a projection projecting outwardly as viewed in the cross section and extending in the advancing direction. The insertion unit includes a tapered part of a diameter decreasing gradually toward a tip. When the insertion unit and a part of the body unit are inserted into a vessel, the projection of the anastomosis assist part of the body unit abuts on the inner wall of the vessel. This makes it unlikely that the inner wall of the vessel will stick to the body unit at a site other than a point abutting on the projection.

Abstract: An organ container includes a bottomed tubular outer container and a bottomed tubular inner container that is fitted into the outer container. A fluid flow path is formed between an outer peripheral surface of the inner container and an inner peripheral surface of the outer container. The outer container has an inlet that communicates between the fluid flow path and the outside, and an outlet that communicates between the fluid flow path and the outside.

Abstract: A perfusion apparatus includes a reservoir and a perfusion-liquid feeding path that feeds a perfusion liquid from the reservoir to an organ. The perfusion-liquid feeding path includes a feeding pipe and a deaeration unit that is interposed in the feeding pipe and includes an air chamber and a deaeration pump. The deaeration pump is a roller tube pump in which a plurality of rollers squeeze a flexible gas pipe while rotating, to cause a flow of gas in the gas pipe, and discharges gas from a gas layer in an upper portion of the air chamber to outside. This makes it possible to discharge gas in the air chamber while keeping the perfusion-liquid feeding path hermetic. Therefore, it is possible to remove bubbles in the perfusion liquid fed to the organ without limiting the height of the organ and without stopping feeding the perfusion liquid to the organ.

Abstract: A perfusion device includes first inlet piping that connects a reservoir and a portal vein, second inlet piping that connects the reservoir and a hepatic artery, a first pump that produces a flow in the first inlet piping, and a second pump that produces a flow in the second inlet piping. The first and second pumps are of the same type, each having a rotating portion for solution sending. The rotating portion of the first pump has a greater diameter than the rotating portion of the second pump. Thus, even if the first and second pumps make the same number of rotations, the ratio of the flow rate of the perfusate between the first inlet piping and the second inlet piping can be made almost constant. Accordingly, the perfusate is supplied under appropriate conditions to the portal vein and the hepatic artery with a simple configuration.

Abstract: An organ container includes flexible films and a tube holder. The films hold an organ in contact with the surface of the organ. The tube holder holds tubes that extend between the organ in the films and an outside of the films. This makes it possible to hold and preserve the organ while allowing a liquid to be perfused through the organ via the tubes. It is also possible to reduce movements of the organ relative to the organ container and to reduce damage to the organ.

Abstract: A perfusion method includes a) cleaning a blood vessel of an organ by causing a first perfusate to flow into the blood vessel and letting the first perfusate out of the organ through the blood vessel, and b) after the operation a), preserving the organ while causing a second perfusate to flow into the blood vessel and letting the second perfusate out of the organ through the blood vessel. The first perfusate and the second perfusate each contain a biocompatible solution and a serine protease and have an osmotic pressure ratio higher than or equal to 1 and lower than or equal to 5 relative to the saline solution. The concentration of the serine protease in the second perfusate is lower than that in the first perfusate. Accordingly, it is possible to dissolve thrombi in the blood vessel or prevent the formation of new thrombi during organ perfusion treatment.

Abstract: An anastomosis assist tool comprises a body unit extending in a predetermined advancing direction, and an insertion unit arranged at the tip of the body unit. The body unit includes an anastomosis assist part having an approximately constant cross-sectional shape in a plane perpendicular to the advancing direction. The anastomosis assist part includes a projection projecting outwardly as viewed in the cross section and extending in the advancing direction. The insertion unit includes a tapered part of a diameter decreasing gradually toward a tip. When the insertion unit and a part of the body unit are inserted into a vessel, the projection of the anastomosis assist part of the body unit abuts on the inner wall of the vessel. This makes it unlikely that the inner wall of the vessel will stick to the body unit at a site other than a point abutting on the projection.

Abstract: An organ container includes a pouch-shaped body. The body has an opening and is capable of storing an organ that is inserted from the opening into an inner space. The body is formed of a styrene elastomer. The body has inner and outer surfaces each having a uneven shape. This structure suppresses a temperature rise in the organ stored in the body and reduces damage to the organ when some sort of impacts is applied to the organ. Moreover, the uneven shape of the inner surface of the body allows holding of a low-temperature preservation solution and thereby improves insulation effectiveness of the organ. The uneven shape of the outer surface of the body facilitates the surgeon's handling of the organ container and thereby improves workability.

Abstract: A frame includes a ring-shaped body part locatable to surround the periphery of an organ, and at least one tube clamp part mounted on the body part. Each tube clamp part includes a tube holder that holds a tube. The tube clamp part is mounted so as to be movable in the circumferential direction of the body part. Thus, a tube connected to the organ can be fixed at an appropriate position to the tube clamp part. This stabilizes the relative positions of the organ and the tube. Accordingly, it is possible to reduce the probability of the organ becoming damaged due to a strain on the organ.

Abstract: An organ container includes a bag-shaped or tube-shaped insulating sheet. The insulating sheet has an opening and is capable of containing an organ inserted in an inner space through the opening. The insulating sheet is formed of an extra flexible material. The insulating sheet has a hardness less than or equal to F45 according to a durometer hardness test compliant with JIS K 6253-3:2012. Accordingly, in the transplantation of an organ with a variety of sizes and shapes into a recipient, the organ container is capable of covering the surface of the organ along the surface of the organ while holding the organ. The organ container suppresses a further outward spread of the organ, thereby ensuring the field of operation and reducing the possibility of interfering with the work of a surgeon.

Abstract: An organ preservation system includes an organ container, an organ holder, a liquid supply tube, a drainage tube, and a pressure regulator. The organ container has a closed organ preservation space. The organ holder holds an organ in the organ preservation space. The liquid supply tube supplies a liquid to the organ. The drainage tube drains the liquid from the organ. The pressure regulator regulates air pressure in the organ preservation space. The organ container includes first to third connectors providing communication between the organ preservation space and an exterior space. The first, second, and third connectors are detachably connected to a liquid supply tube, a drainage tube, and a suction tube, respectively. When the organ is preserved ex vivo while being perfused with the liquid, the organ can be connected with ease to the tubes, and this ensures hermetical sealing of the space where the organ is preserved.

Abstract: There is provided a technique of, when an organ is preserved outside a body while being perfused with a liquid, ensuring the flow rate of the liquid flowing in the organ while suppressing a rise in pressure in the liquid. An organ preservation system includes an organ container, an organ holder, a liquid supply tube, a drainage tube, and an atmospheric pressure regulator. The organ container is capable of having therein an organ preservation space that is a confined space. The organ holder holds the organ in the organ preservation space. The liquid supply tube supplies a liquid to the organ held by the organ holder. The drainage tube discharges a liquid from the organ held by the organ holder. The atmospheric pressure regulator regulates atmospheric pressure in the organ preservation space. By regulating atmospheric pressure in the organ preservation space, it is possible to adjust a pressure in the liquid flowing in the organ.

Abstract: A tube is flexible, and includes a tubular outer peripheral surface and a tubular inner peripheral surface. The outer peripheral surface includes corner portions protruding outwardly. The inner peripheral surface includes first arcuate portions positioned inside the corner portions and having a radius of curvature greater than that of the corner portions. In the tube having such a shape, opposed portions of the inner peripheral surface are less prone to be close to each other when an external force is applied to the tube or when the tube is locally bent. This restrains an internal flow passage of the tube from being blocked.

Abstract: An organ container has a contractible and expandable pouch-shaped body having an opening. Under no-load conditions, the opening has a maximum width smaller than a maximum width of the body. The opening is expandable up to a state in which the maximum width of the opening is greater than the maximum width of the body. The body has an inner surface that includes a first region having a smooth curved surface and a second region having an uneven shape. The uneven shape of the inner surface of the body allows a preservation solution to protrude into interstices between an organ and the inner surface and thereby improves a thermal insulating effect. Moreover, by providing the smooth first region, generation of remaining traces can be suppressed. Accordingly, it is possible to effectively suppress a temperature rise in the organ and to reduce damage to the organ.

Abstract: A perfusion lumen is connected to at least one perfusion blood vessel among a plurality of blood vessels that extends from a branch of a plurality of blood vessels protruding from a liver, the branch existing on a distal side viewed from the liver, to a further distal side viewed from the liver. The perfusion lumen is supplied with perfusate to perfuse the liver and maintain the condition of the liver. Among blood vessels that are not connected to the perfusion lumen, at least one conserved blood vessel is obstructed and conserved for anastomosis to a blood vessel of the living body. Accordingly, the perfusion state of the liver is maintained even during anastomosis to the blood vessels of the living body. This enables anastomosis to the blood vessels of the living body while maintaining the perfusion state of the liver.

Abstract: An organ container includes a bottomed tubular outer container and a bottomed tubular inner container that is fitted into the outer container. A fluid flow path is formed between an outer peripheral surface of the inner container and an inner peripheral surface of the outer container. The outer container has an inlet that communicates between the fluid flow path and the outside, and an outlet that communicates between the fluid flow path and the outside.

Abstract: A frame includes a ring-shaped body part locatable to surround the periphery of an organ, and at least one tube clamp part mounted on the body part. Each tube clamp part includes a tube holder that holds a tube. The tube clamp part is mounted so as to be movable in the circumferential direction of the body part. Thus, a tube connected to the organ can be fixed at an appropriate position to the tube clamp part. This stabilizes the relative positions of the organ and the tube. Accordingly, it is possible to reduce the probability of the organ becoming damaged due to a strain on the organ.

Abstract: An organ container includes flexible films and a tube holder. The films hold an organ in contact with the surface of the organ. The tube holder holds tubes that extend between the organ in the films and an outside of the films. This makes it possible to hold and preserve the organ while allowing a liquid to be perfused through the organ via the tubes. It is also possible to reduce movements of the organ relative to the organ container and to reduce damage to the organ.

Abstract: An anastomosis assist tool comprises a body unit extending in a predetermined advancing direction, and an insertion unit arranged at the tip of the body unit. The body unit includes an anastomosis assist part having an approximately constant cross-sectional shape in a plane perpendicular to the advancing direction. The anastomosis assist part includes a projection projecting outwardly as viewed in the cross section and extending in the advancing direction. The insertion unit includes a tapered part of a diameter decreasing gradually toward a tip. When the insertion unit and a part of the body unit are inserted into a vessel, the projection of the anastomosis assist part of the body unit abuts on the inner wall of the vessel. This makes it unlikely that the inner wall of the vessel will stick to the body unit at a site other than a point abutting on the projection.