Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.

Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Abstract: A system for providing electrical stimulation comprises a garment, wherein the garment includes a base material that is nonconductive and elastic. The garment may include a plurality of conductive electrodes secured to the base material, and at least one conductive path secured to the base material, wherein the at least one conductive path is configured to couple at least one conductive electrode of the plurality of conductive electrodes. The garment may include an intermediate layer disposed between at least one conductive electrode of the plurality of conductive electrodes and the base material.

Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Abstract: An adapter system for facilitating collection of colostrum from a breast may include an adapter, a removable reservoir and a hand-expression funnel. The adapter may include a first open end for connecting to a breast shield of a breast pump system, a second open end for connecting to a breast pump connector of the breast pump system, and a third open end, disposed between the first and second open ends. The removable reservoir may include a wide end for removably attaching to the third open end and a narrow end for attaching to a colostrum delivery device. The hand-expression funnel may include a wide end for receiving colostrum and a narrow end for attaching to the colostrum delivery device. In some embodiments, the colostrum delivery device is a syringe.

Abstract: A system and method configured to provide a mechanism allowing a third party, not involved in a payment transaction made between a merchant and a payment account, to provide a credit to the payment account as an offer benefit redeemed in view of the payment transaction. The mechanism includes a transaction handler of a payment processing network configured to provide transaction information relevant to the offer to the third party. If the third party determines that a qualifying transaction in the payment account is entitled to the benefit, the third party communicates a request, via an application programming interface (API), to a portal of the transaction handler for a credit to the payment account for the payment transaction; if the request is approved, in response, the transaction handler generates a credit transaction for the payment account.

Abstract: A system and method configured to provide a mechanism allowing a third party, not involved in a payment transaction made between a merchant and a payment account, to provide a credit to the payment account as an offer benefit redeemed in view of the payment transaction. The mechanism includes a transaction handler of a payment processing network configured to provide transaction information relevant to the offer to the third party.

Abstract: An apparatus for dispensing ophthalmic lens packages comprises a first spool and a second spool rotatably mounted to a least one support, and a flexible sheet, having a hole, that coils or uncoils around the spools in response to their rotation. A cartridge with a hole and a means for releasably holding a package is attached to the flexible sheet, and the hole of the flexible sheet and the hole of the cartridge are aligned to permit an object to pass therethrough. A pushing means, between said first spool and said second spool, extends a pushing member through the hole of the flexible sheet and the hole of the cartridge. A scanning means moves in response to an electrical or mechanical signal between said first spool and said second spool.

Abstract: An adapter system for facilitating collection of colostrum from a breast may include an adapter, a removable reservoir and a hand-expression funnel. The adapter may include a first open end for connecting to a breast shield of a breast pump system, a second open end for connecting to a breast pump connector of the breast pump system, and a third open end, disposed between the first and second open ends. The removable reservoir may include a wide end for removably attaching to the third open end and a narrow end for attaching to a colostrum delivery device. The hand-expression funnel may include a wide end for receiving colostrum and a narrow end for attaching to the colostrum delivery device. In some embodiments, the colostrum delivery device is a syringe.

Abstract: A system and method includes an input device, a client device registering an input device to form an association and a server device registering the input device and registering the association with the server device. The input device broadcasts a control signal to the client device and the server device. The server device receiving the control signal directly from the input device. The server device communicates a response signal to the client device in response to the receiving the control signal.

Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Abstract: A device includes a connector and a detector device. The connector includes at least one first-type pin and at least one second-type pin. The connector is capable of being connected to a corresponding connector of a solid-state drive (SSD) device. The detector device controls the at least one first-type pin to be coupled to a first power supply voltage based on, at least in part, the at least one second-type pin is connected to a second power supply voltage while the corresponding connector of the SSD device is connected to the first connector. If the at least one second-type pin is detected as being connected to a third power supply voltage different from the second power supply voltage while the corresponding connector of the SSD device is connected to the first connector, the detector device controls the at least one first-type pin to be in a non-connected state.

Abstract: The present invention is directed to the treatment of crop plants with 3?-methyl-(S)-abscisic acid, 3?-propargyl-(S)-abscisic acid, and/or salts thereof in order to improve the plants' environmental stress tolerance.

Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.

Abstract: A method for enhancing efficiency of a computerized electronic signature system by facilitating collection of signatures from multiple signatories is described. The method may initially involve verifying an identity of a first signatory by receiving data from the first signatory electronically, providing a document to the first signatory, receiving a first electronic signature on the document from the first signatory, and receiving a selection from the first signatory of a second signatory to sign the document as a witness. The method may then involve verifying an identity of the second signatory by receiving data from the second signatory electronically, providing the document to the second signatory, receiving a second electronic signature from the second signatory, providing a completed document, including the first signature and the second signature, and notifying the first signatory and the second signatory that the completed document is completed.

Abstract: The invention relates to a novel class of (S)-3?-substituted-abscisic acid derivatives and (±)-3?-substituted-abscisic acid derivatives, and methods of synthesizing the derivatives.

Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.

Abstract: A novel fungal strain of Tolypocladium album (synonym Chaunopycnis alba) is disclosed that has enhanced toxicity against insects and mites. This novel Tolypocladium album strain is capable of producing terpendoles A, C, I, J, K, N, O and P through fermentation and does not produce nalanthalide.

Abstract: The present invention relates to compositions and methods for molecular profiling and diagnostics for genetic disorders and cancer, including but not limited to gene expression product markers associated with cancer or genetic disorders. In particular, the present invention provides algorithms and methods of classifying cancer, for example, thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis.