Patents by Inventor Taco Gilles Uil

Taco Gilles Uil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adenovirus and uses thereof
    Patent number: 11872281
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: January 16, 2024
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Taco Gilles Uil, Soumitra Roy, Selina Khan, Jerôme H. H. V. Custers
  • Recombinant adenoviral vector expressing Zika antigen with improved productivity
    Patent number: 11713469
    Abstract: Provided herein are adenoviral vectors comprising nucleotide sequences encoding a Zika virus M and Env antigen, wherein the nucleotide sequence encoding the Zika virus M and Env antigen is operably linked to a cytomegalovirus (CMV) promoter comprising at least one tetracycline operator (TetO) motif. Also provided herein are pharmaceutical compositions comprising the adenoviral vectors, methods of producing the adenoviral vectors, methods of preventing Zika virus or the progression of Zika virus in a subject in need thereof, and kits comprising the adenoviral vectors and host cells.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: August 1, 2023
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventor: Taco Gilles Uil
  • Adenovirus vectors and uses thereof
    Patent number: 11459583
    Abstract: Provided herein are chimeric adenoviral vectors. The provided chimeric adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: October 4, 2022
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Taco Gilles Uil, Soumitra Roy, Jort Vellinga, Selina Khan, Jerome H. Hv. Custers
  • Adenovirus and uses thereof
    Patent number: 11236361
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: February 1, 2022
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Taco Gilles Uil, Soumitra Roy, Selina Khan, Jerôme H. H. V. Custers
  • Recombinant Adenoviral Vector Expressing Zika Antigen with Improved Productivity
    Publication number: 20210317477
    Abstract: Provided herein are adenoviral vectors comprising nucleotide sequences encoding a Zika virus M and Env antigen, wherein the nucleotide sequence encoding the Zika virus M and Env antigen is operably linked to a cytomegalovirus (CMV) promoter comprising at least one tetracycline operator (TetO) motif. Also provided herein are pharmaceutical compositions comprising the adenoviral vectors, methods of producing the adenoviral vectors, methods of preventing Zika virus or the progression of Zika virus in a subject in need thereof, and kits comprising the adenoviral vectors and host cells.
    Type: Application
    Filed: July 19, 2019
    Publication date: October 14, 2021
    Inventor: Taco Gilles Uil
  • Adenovirus and uses thereof
    Patent number: 11142551
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: October 12, 2021
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Taco Gilles Uil, Soumitra Roy, Selina Khan, Jerôme H. H. V. Custers
  • POTENT AND SHORT PROMOTER FOR EXPRESSION OF HETEROLOGOUS GENES
    Publication number: 20210261984
    Abstract: The invention provides an AoHV-1 promoter for use with plasmid vectors, viral vectors, viruses, and cell lines comprising the AoHV-1 promoter operably linked to a transgene. The invention also provides methods of making and using recombinant plasmid vectors, viral vectors, viruses, and cell lines comprising the AoHV-1 promoter operably linked to a transgene.
    Type: Application
    Filed: May 7, 2021
    Publication date: August 26, 2021
    Inventors: Kerstin WUNDERLICH, Taco Gilles UIL, Jort VELLINGA, Barbara Petronella SANDERS, Remko VAN DER VLUGT
  • ADENOVIRUS AND USES THEREOF
    Publication number: 20210214398
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Application
    Filed: October 30, 2018
    Publication date: July 15, 2021
    Inventors: Taco Gilles UIL, Soumitra ROY, Selina KHAN, Jerôme H, H, V, CUSTERS
  • ADENOVIRUS AND USES THEREOF
    Publication number: 20210198690
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Application
    Filed: October 30, 2018
    Publication date: July 1, 2021
    Inventors: Taco Gilles UIL, Soumitra ROY, Selina KHAN, Jerôme H, H, V, CUSTERS
  • Therapeutic HPV16 vaccines
    Patent number: 11040096
    Abstract: Provided is designer nucleic acid constructs and polypeptides that can be used as therapeutic vaccines against HPV16.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: June 22, 2021
    Inventors: Evelien Margaretha Bunnik, Jerôme Hubertina Henricus Victor Custers, Gerrit Christiaan Scheper, Koen Oosterhuis, Taco Gilles Uil, Selina Khan
  • Potent and short promoter for expression of heterologous genes
    Patent number: 11034978
    Abstract: The invention provides an AoHV-1 promoter for use with plasmid vectors, viral vectors, viruses, and cell lines comprising the AoHV-1 promoter operably linked to a transgene. The invention also provides methods of making and using recombinant plasmid vectors, viral vectors, viruses, and cell lines comprising the AoHV-1 promoter operably linked to a transgene.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: June 15, 2021
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Kerstin Wunderlich, Taco Gilles Uil, Jort Vellinga, Barbara Petronella Sanders, Remko Van Der Vlugt
  • Therapeutic HPV18 vaccines
    Patent number: 10844096
    Abstract: Provided is designer nucleic acid constructs and polypeptides that can be used as therapeutic vaccines against HPV18 and/or HPV16.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: November 24, 2020
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Evelien Margaretha Bunnik, Jerôme Hubertina Henricus Victor Custers, Gerrit Christiaan Scheper, Koen Oosterhuis, Taco Gilles Uil, Selina Khan
  • ADENOVIRUS VECTORS AND USES THEREOF
    Publication number: 20200347405
    Abstract: Provided herein are chimeric adenoviral vectors. The provided chimeric adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Application
    Filed: October 30, 2018
    Publication date: November 5, 2020
    Inventors: Taco Gilles UIL, Soumitra ROY, Jort VELLINGA, Selina KHAN, Jerome H.HV. Custers
  • ADENOVIRUS AND USES THEREOF
    Publication number: 20200323977
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Application
    Filed: October 30, 2018
    Publication date: October 15, 2020
    Inventors: Taco Gilles UIL, Soumitra ROY, Selina KHAN, Jerôme H.H.V. CUSTERS
  • HPV vaccines
    Patent number: 10744196
    Abstract: The present invention relates to novel vaccines against Human papillomavirus (HPV) infections, based on recombinant capsid-display adenovirus vectors. Described are capsid modified replication deficient adenovirus particles encoding and displaying multiple HPV L2 antigenic fragments, via a minor capsid protein IX, and their use for eliciting an immune response in order to provide protection against infections from multiple HPV types.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: August 18, 2020
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Marija Vujadinovic, Taco Gilles Uil, Koen Oosterhuis, Jort Vellinga, Jerôme Hubertina Henricus Victor Custers
  • THERAPEUTIC HPV16 VACCINES
    Publication number: 20200164057
    Abstract: Provided is designer nucleic acid constructs and polypeptides that can be used as therapeutic vaccines against HPV16.
    Type: Application
    Filed: January 29, 2020
    Publication date: May 28, 2020
    Inventors: Evelien Margaretha BUNNIK, Jerôme Hubertina Henricus Victor CUSTERS, Gerrit Christiaan SCHEPER, Koen OOSTERHUIS, Taco Gilles UIL, Selina KHAN
  • Therapeutic HPV16 vaccines
    Patent number: 10555996
    Abstract: Provided is designer nucleic acid constructs and polypeptides that can be used as therapeutic vaccines against HPV16.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: February 11, 2020
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Evelien Margaretha Bunnik, Jerôme Hubertina Henricus Victor Custers, Gerrit Christiaan Scheper, Koen Oosterhuis, Taco Gilles Uil, Selina Khan
  • HPV VACCINES
    Publication number: 20190240312
    Abstract: The present invention relates to novel vaccines against Human papillomavirus (HPV) infections, based on recombinant capsid-display adenovirus vectors. Described are capsid modified replication deficient adenovirus particles encoding and displaying multiple HPV L2 antigenic fragments, via a minor capsid protein IX, and their use for eliciting an immune response in order to provide protection against infections from multiple HPV types.
    Type: Application
    Filed: July 11, 2017
    Publication date: August 8, 2019
    Inventors: Marija VUJADINOVIC, Taco Gilles UIL, Koen OOSTERHUIS, Jort VELLINGA, Jerôme Hubertina Henricus Victor CUSTERS
  • THERAPEUTIC HPV18 VACCINES
    Publication number: 20190202869
    Abstract: Provided is designer nucleic acid constructs and polypeptides that can be used as therapeutic vaccines against HPV18 and/or HPV16.
    Type: Application
    Filed: March 19, 2019
    Publication date: July 4, 2019
    Inventors: Evelien Margaretha BUNNIK, Jerôme Hubertina Henricus Victor CUSTERS, Gerrit Christiaan SCHEPER, Koen OOSTERHUIS, Taco Gilles UIL, Selina KHAN
  • Therapeutic HPV18 vaccines
    Patent number: 10287323
    Abstract: Provided is designer nucleic acid constructs and polypeptides that can be used as therapeutic vaccines against HPV18 and/or HPV16.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: May 14, 2019
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Evelien M. Bunnik, Jerome Hubertina Henricus Victor Custers, Gerrit C. Scheper, Koen Oosterhuis, Taco Gilles Uil, Selina Khan