Abstract: A molding material supply device and a molding material supply method capable of supplying a degassed molding material to a molding apparatus at a desired timing are desired. According to the molding material supply device and method of the disclosure, a first discharge member is driven to discharge a molding material accommodated in a first accommodation member to a second discharge member through a through hole of a die, and a second discharge member configured by the first accommodation member and the die advances to discharge the molding material having been degassed in the second accommodation member to the molding apparatus from a molding material supply port.

Abstract: A sound signal output method of outputting sound to a plurality of areas comprises obtaining a sound signal of a sound source, receiving a setting of reproduction information indicating whether or not to output the sound signal of the above-mentioned sound source to each of the plurality of areas where the above-mentioned sound signal is to be output, and outputting the above-mentioned reproduction information and the above-mentioned sound signal, or reproducing the above-mentioned sound signal based on the above-mentioned reproduction information.

Abstract: An information processing method receives settings of a plurality of pieces of information on a plurality of physical spaces that respectively correspond to a plurality of pieces of information on a plurality of logical spaces, receives a first group of a plurality of pieces of first acoustic image localization information that indicates a position of an acoustic image to be localized in each of the plurality of logical spaces using first coordinates in the plurality of logical spaces, receives a change in one piece of first acoustic image localization information, among the first group of the plurality of pieces of first acoustic image localization information, changes other pieces of first acoustic image localization information, among the first group of the plurality of pieces of first acoustic image localization, in response to the received change in the one piece of first acoustic image localization information, and transforms the first group of the plurality of pieces of first acoustic image localizatio

Abstract: A live data distribution method obtains information on a sound source according to sound generated at the first venue, and information on space reverberation, as distribution data, distributes the distribution data to the second venue, and renders the distribution data and providing sound according to the distribution data at the second venue.

Abstract: A live data distribution method obtains first sound source information according to sound of a first sound source generated at a first location of the first venue and position information of the first sound source, and second sound source information according to a second sound source including an ambient sound generated at a second location of the first venue, as distribution data, distributes the distributed data to the second venue, and renders the distribution data and providing first sound of the first sound source having been performed with localization processing based on the position information of the first sound source, and second sound of the second sound source, at the second venue.

Abstract: An information processing method includes: receiving first space information including a first coordinate system of one of a logical space or a physical space, and second space information including a second coordinate system of the other of the logical space or the physical space; receiving first sound localization information indicating a position where a sound image is to be localized in the first coordinate system; and transforming the first sound localization information into second sound localization information indicating a position where the sound image is to be localized in the second coordinate system.

Abstract: A backflow prevention device of a light metal injection device and a backflow prevention method thereof of the disclosure include: a valve which has a valve body made of a corrosion-resistant and heat-resistant steel and a valve seat made of a ceramic, and in which the valve body advances and is seated on the valve seat to close a communication path communicating a melting unit and an injection unit, and the valve body retracts and is separated from the valve seat to open the communication path; a valve body drive device which moves a drive body to which the valve body is connected forward and backward; a position sensor which detects that the drive body has reached at least a predetermined advance limit position; and a valve body drive control device which controls the valve body drive device based on a signal of the position sensor.

Abstract: A backflow prevention device of a light metal injection device and a backflow prevention method thereof of the disclosure include: a valve which has a valve body made of a corrosion-resistant and heat-resistant steel and a valve seat made of a ceramic, and in which the valve body advances and is seated on the valve seat to close a communication path communicating a melting unit and an injection unit, and the valve body retracts and is separated from the valve seat to open the communication path; a valve body drive device which moves a drive body to which the valve body is connected forward and backward; a position sensor which detects that the drive body has reached at least a predetermined advance limit position; and a valve body drive control device which controls the valve body drive device based on a signal of the position sensor.

Abstract: A sound signal output method of outputting sound to a plurality of areas comprises obtaining a sound signal of a sound source, receiving a setting of reproduction information indicating whether or not to output the sound signal of the above-mentioned sound source to each of the plurality of areas where the above-mentioned sound signal is to be output, and outputting the above-mentioned reproduction information and the above-mentioned sound signal, or reproducing the above-mentioned sound signal based on the above-mentioned reproduction information.

Abstract: An information processing method includes: receiving first space information including a first coordinate system of one of a logical space or a physical space, and second space information including a second coordinate system of the other of the logical space or the physical space; receiving first sound localization information indicating a position where a sound image is to be localized in the first coordinate system; and transforming the first sound localization information into second sound localization information indicating a position where the sound image is to be localized in the second coordinate system.

Abstract: A molding material supply device and a molding material supply method capable of supplying a degassed molding material to a molding apparatus at a desired timing are desired. According to the molding material supply device and method of the disclosure, a first discharge member is driven to discharge a molding material accommodated in a first accommodation member to a second discharge member through a through hole of a die, and a second discharge member configured by the first accommodation member and the die advances to discharge the molding material having been degassed in the second accommodation member to the molding apparatus from a molding material supply port.

Abstract: The audio signal processing apparatus includes at least one bus a network interface, a user interface, a display, and a processor. The network interface outputs an audio signal through a second plurality of audio channels through a network. The user interface receives an operation from a user. The processor receives, from a destination device to which the audio signal is output, information about the number of available output channels of the destination device, controls the display to display a virtual bus representing the output channels of the destination device, received information regarding the number of output channels, receives input setting of a correspondence relationship between the second plurality of audio channels of the audio signal and the virtual bus, generates setting information according to the received input setting, and sends the audio signal outputted from the network interface the audio signal and the setting information to the destination device.

Abstract: The audio signal processing apparatus includes at least one bus a network interface, a user interface, a display, and a processor. The network interface outputs an audio signal through a second plurality of audio channels through a network. The user interface receives an operation from a user. The processor receives, from a destination device to which the audio signal is output, information about the number of available output channels of the destination device, controls the display to display a virtual bus representing the output channels of the destination device, received information regarding the number of output channels, receives input setting of a correspondence relationship between the second plurality of audio channels of the audio signal and the virtual bus, generates setting information according to the received input setting, and sends the audio signal outputted from the network interface the audio signal and the setting information to the destination device.

Abstract: The present invention provides a crosslinked hyaluronic acid composition including self-crosslinking hyaluronic acid particles having an equilibrium swelling capacity of 3-fold to 10-fold, and an aqueous solvent, wherein a dry weight of the self-crosslinking hyaluronic acid particles based on the total volume of the crosslinked hyaluronic acid composition is 3 w/v % to 8 w/v %. The crosslinked hyaluronic acid composition of the invention uses self-crosslinking hyaluronic acid particles of which the equilibrium swelling capacity is within the above predetermined range. Accordingly, the viscosity does not sharply increase even if the concentration thereof is increased. Therefore, if the crosslinked hyaluronic acid composition is applied to an injection, it is possible to obtain a sufficient curative effect on knee osteoarthritis even with a small frequency of administration.

Abstract: A crosslinking reaction and a reaction for reducing molecular weight that take place in a hyaluronic acid-methotrexate conjugate upon irradiation with light are suppressed to improve the photostability of the conjugate. Specifically, a substance having a quenching effect and/or a radical scaveng effect is added to a pharmaceutical composition containing the hyaluronic acid-methotrexate conjugate.

Abstract: A mounting ring with which an engaging hook of a fall-preventing member is to be engaged and a flexible handle member are fixed within an area of a cabinet section that is located upward of a first plane passing through the position of a center of gravity of the cabinet section generally in parallel to the bottom surface of the cabinet section and located to one side of a second plane passing through the position of the center of gravity in intersecting relation to the first plane. The speaker unit hung by the handle member being held with a hand of a human operator is inclined, so that the mounting ring is oriented upward near the hand. Thus, the human operator can perform with ease an operation for engaging the engaging hook with the mounting ring with one hand while holding the handle member with the other hand.

Abstract: A mounting ring with which an engaging hook of a fall-preventing member is to be engaged and a flexible handle member are fixed within an area of a cabinet section that is located upward of a first plane passing through the position of a center of gravity of the cabinet section generally in parallel to the bottom surface of the cabinet section and located to one side of a second plane passing through the position of the center of gravity in intersecting relation to the first plane. The speaker unit hung by the handle member being held with a hand of a human operator is inclined, so that the mounting ring is oriented upward near the hand. Thus, the human operator can perform with ease an operation for engaging the engaging hook with the mounting ring with one hand while holding the handle member with the other hand.

Abstract: The present invention provides a crosslinked hyaluronic acid composition including self-crosslinking hyaluronic acid particles having an equilibrium swelling capacity of 3-fold to 10-fold, and an aqueous solvent, wherein a dry weight of the self-crosslinking hyaluronic acid particles based on the total volume of the crosslinked hyaluronic acid composition is 3 w/v % to 8 w/v %. The crosslinked hyaluronic acid composition of the invention uses self-crosslinking hyaluronic acid particles of which the equilibrium swelling capacity is within the above predetermined range. Accordingly, the viscosity does not sharply increase even if the concentration thereof is increased. Therefore, if the crosslinked hyaluronic acid composition is applied to an injection, it is possible to obtain a sufficient curative effect on knee osteoarthritis even with a small frequency of administration.

Abstract: An object of the present invention is to provide a hyaluronic acid-methotrexate conjugate useful as a therapeutic drug for joint diseases. There is provided a hyaluronic acid-methotrexate conjugate useful as a therapeutic drug for joint diseases, wherein methotrexate is conjugated with a carboxyl group of hyaluronic acid through a linker containing a peptide chain consisting of 1 to 8 amino acids.

Abstract: A crosslinking reaction and a reaction for reducing molecular weight that take place in a hyaluronic acid-methotrexate conjugate upon irradiation with light are suppressed to improve the photostability of the conjugate. Specifically, a substance having a quenching effect and/or a radical scaveng effect is added to a pharmaceutical composition containing the hyaluronic acid-methotrexate conjugate.