Abstract: The present invention relates to methods and pharmaceutical compositions for treating obesity or obesity-related disorders in a subject suffering from or predisposed to developing obesity or an obesity-related disorder, or for inhibiting the infectivity of HIV, by administering oleuropein, an analogue or derivative thereof, or the major metabolites of oleuropein including oleuropein aglycone, hydroxytyrosol, and elenolic acid or their analogues, or derivatives thereof, an iridoid glycoside, or a secoiridoid glycoside or analogues or derivatives thereof, or any combination of the foregoing including olive leave extract. The invention also relates to methods for screening/diagnosing a subject having, or predisposed to having obesity or a related disorder by measuring the expression profiles of an adipogenic gene selected from PPAR?2, LPL and ?P2 gene and gene product, or other adipogenic, lipogenic, or lipolytic genes and gene products in an individual.

Abstract: The present invention provides a method of preparing an alkylamine derivates which hardly generates impurities and enables mass production with high purity.

Abstract: The present invention relates to methods of detecting, in a sample, embryonic stem cells, induced pluripotent stem cells, and/or cells undergoing reprogramming to produce induced pluripotent stem cells. These methods include providing a sample potentially containing such cells and providing a rosamine derivative compound of the formula (I): where the rosamine derivative compound selectively produces fluorescent signals for embryonic stem cells, induced pluripotent stem cells, and/or cells undergoing reprogramming to produce induced pluripotent stem cells. These methods also include the steps of contacting the sample with the rosamine derivative compound and detecting the presence of the embryonic stem cells, induced pluripotent stem cells, and/or cells undergoing reprogramming to produce induced pluripotent stem cells based on fluorescent signals emitted by the sample following said contacting.

Abstract: An event processing method includes receiving an event from an event source and identifying an event population and non-event population based on the received event, such that the event population includes a plurality of events and the non-event population includes a plurality of non-events. The method further includes identifying an event feedback group from the events of the identified event population, such that the event feedback group identifies a number of events of the identified event population that have performed a required operation, and determining a ratio of event feedback, the ratio of the event feedback being a ratio of the number of events identified by the event feedback group to a number of the events of the identified event population.

Abstract: A data processing method of a memory controller includes receiving first partial data of a last sector data among a plurality of sector data to be stored in an n-th page of a non-volatile memory in a program operation; padding the first partial data with first dummy data and generating a first error correction code (ECC) parity in the program operation; and transferring the first partial data and the first ECC parity to the non-volatile memory in the program operation, while refraining from transferring the first dummy data to the non-volatile memory. Related devices and systems are also described.

Abstract: A method and apparatus for decoding of tailbiting convolutional codes (TBCC) are disclosed. The proposed modified maximum-likelihood TBCC decoding technique preserves error correction performance of optimal maximum-likelihood based TBCC decoding, while the computational complexity is substantially decreased since a reduced number of decoding states has been evaluated. Compare to other sub-optimal TBCC decoding algorithms, modified maximum-likelihood TBCC decoding achieves improved packet error rate performance with similar computational complexity.

Abstract: The present invention is directed toward benzimidazolium dye compounds of formula (I) as follows: wherein, n is an integer from 2-10, m is an integer from 2-10, X1 and X2 are independently a halogen, Q is H or a resin, and R is (aromatic)o-(linker)p-with the linker being saturated or unsaturated C1-C5 hydrocarbons, each aromatic independently being a substituted or unsubstituted aromatic or heteroaromatic, o being 1 or 2, and p being 0 or 1. Methods of making and using these compounds are also disclosed.

Abstract: The present invention discloses a series of alkylamino BODIPY dyes, methods for preparing a library of alkyl-amino BODIPY dyes via solid-phase synthesis, and the use of the alkyl-amino BODIPY dyes as fluorescent sensors for protein detection, cell imaging and cytometry applications, and staining of certain cell line.

Abstract: Provided are spectacle frames and a manufacturing method thereof, in which a front of the spectacle frames is formed by processing a celluloid plate of plastic, and temples are mounted on the front of the spectacle frames, thereby manufacturing the spectacle frames using the celluloid plate. The present invention does not require injection molding and an injection mold, and by processing both a hinge part and the front of the spectacle frames, the spectacle frames that can be applied to various wearers' face sizes can be manufactured with only the front of the frames having a single size. Also, by merely changing a design, various designs of the spectacle frames can be realized with only the front of the frames having a single size.

Abstract: A propeller shaft seal for sealing a propeller shaft in a stern tube, comprising a bi-direction rotational sealing body being fitted within the stern tube and wrapped around the propeller shaft in its axial direction; wherein the bi-direction rotational sealing body comprising two metallic helical coils stacking together in a way that is mirroring each other; wherein the first and second metallic helical coils being constructed from helically coiled metal tapes of varying widths linked together and coiled into rings and with the rings tightly bounded; and wherein at any one time during operation, a rotational direction of the propeller shaft is same as coiling direction of one of the two metallic helical coils but opposite to that of the other of the two metallic helical coils.

Abstract: The present invention relates to compounds of a general formula (I) having photoluminescence properties. The present invention also relates to applications, such as protein imaging tools, involving such compounds.

Abstract: The present invention relates to a method for manufacturing a micro wire, a sensor including the micro wire, and a method for manufacturing the sensor, having improved production efficiency. According to an embodiment of the present invention, a method for manufacturing a micro wire includes applying a three-dimensional electric field to a solution for forming a micro wire. The method for manufacturing the micro wire may further include providing an electrode assembly comprising a substrate, a first electrode and a second electrode formed on the substrate, and providing the solution to a space. The first electrode and the second electrode may form the space therebetween, and the space may have a first width and a second width that is smaller than the first width. The three-dimensional electric field is applied to the solution by applying a voltage to the first electrode and the second electrode.

Abstract: An axial piston pump, comprising a cylinder block having one or more cylinder bores; and one or more piston assemblies; wherein number of piston assemblies matches number of cylinder bores; wherein each of the piston assemblies having a piston being disposed reciprocating in each of the cylinder bores; and wherein each piston being fitted with a metallic sealing ring, which is a coiled felt seal (CFS), for reducing leakage and keeping concentric of the piston within its corresponding cylinder bore.

Abstract: A propeller shaft seal for sealing a propeller shaft in a stern tube, comprising a bi-direction rotational sealing body being fitted within the stern tube and wrapped around the propeller shaft in its axial direction; wherein the bi-direction rotational sealing body comprising two metallic helical coils stacking together in a way that is mirroring each other; wherein the first and second metallic helical coils being constructed from helically coiled metal tapes of varying widths linked together and coiled into rings and with the rings tightly bounded; and wherein at any one time during operation, a rotational direction of the propeller shaft is same as coiling direction of one of the two metallic helical coils but opposite to that of the other of the two metallic helical coils.

Abstract: The present invention relates to methods and pharmaceutical compositions for treating obesity or obesity-related disorders in a subject suffering from or predisposed to developing obesity or an obesity-related disorder, or for inhibiting the infectivity of HIV, by administering oleuropein, an analogue or derivative thereof, or the major metabolites of oleuropein including oleuropein aglycone, hydroxytyrosol, and elenolic acid or their analogues, or derivatives thereof, an iridoid glycoside, or a secoiridoid glycoside or analogues or derivatives thereof, or any combination of the foregoing including olive leave extract. The invention also relates to methods for screening/diagnosing a subject having, or predisposed to having obesity or a related disorder by measuring the expression profiles of an adipogenic gene selected from PPAR?2, LPL and ?P2 gene and gene product, or other adipogenic, lipogenic, or lipolytic genes and gene products in an individual.

Abstract: The present invention is directed to a fluorescence compound represented by structural Formula (I), with specificity to neural stem cells: I or a pharmaceutically acceptable salt thereof. The variables for structural Formula (I) are defined herein. Also described are methods for detection of neural stem cells, comprising using a compound of structural Formula (I) or pharmaceutically acceptable salts thereof. Compounds of structural Formula (I) can detect and separate neural stem cells without immunostaining, providing a much shorter and more convenient method for detection of neural stem cells.

Abstract: The invention includes a compound represented by the following structural formula: wherein is described herein. The compounds of the invention are useful in staining embryonic stem cells.

Abstract: A memory system is provided. The memory system includes a nonvolatile memory and a controller. The nonvolatile memory includes a memory cell array and a read/write circuit configured to perform a read/write operation in the memory cell array during a read operation. The controller is configured to receive the read data from the nonvolatile memory, perform an error detection and correction operation on the read data. Upon detecting an error in a received portion of the read data, the controller is further configured to halt further transmission of the read data from the nonvolatile memory, perform the error detection and correction operation on the received portion of the read data to correct the detected error. After correcting the detected error in the received portion of the read data, the controller is configured to resume transmission of the read data from the nonvolatile memory.

Abstract: There is provided a method of preparing a surface enhanced Raman spectroscopy (SERS) particle comprising the step of encapsulating a plurality of Raman molecules on the surface of a metallic core with a biocompatible protective shell at an elevated temperature selected to decrease the encapsulation time by more than one-fold relative to an encapsulation performed at 20° C.

Abstract: The present invention generally relates to prostaglandin transport. More specifically, the invention is directed to compounds that inhibit prostaglandin transport and subsequent COX-2 induction, and methods relating thereto.