Patents by Inventor Tae-Woong Koo

Tae-Woong Koo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10998513
    Abstract: A display device is disclosed. In one aspect, the display device includes a flexible substrate capable of being bent in a first direction and an insulating layer including a first opening pattern positioned on the flexible substrate and extending in a second direction crossing the first direction.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: May 4, 2021
    Assignee: Samsung Display Co., Ltd.
    Inventors: Tae Woong Kim, Hyun Woo Koo, Young Gug Seol
  • Publication number: 20150329905
    Abstract: Embodiments of the present invention provide devices methods for sequencing DNA using arrays of reaction cavities containing sensors to monitor changes in solutions contained in the reaction cavities. Additional embodiments provide devices and methods for sequencing DNA using arrays of reaction cavities that allow for optical monitoring of solutions in the reaction cavities. Test and fill reaction schemes are disclosed that allow DNA to be sequenced. By sequencing DNA using parallel reactions contained in large arrays, DNA can be rapidly sequenced.
    Type: Application
    Filed: May 21, 2015
    Publication date: November 19, 2015
    Inventors: Tae-Woong KOO, Salena CHAN, Xing SU, Jingwu ZHANG, Mineo YAMAKAWA, Val M. DUBIN
  • Patent number: 9040237
    Abstract: Embodiments of the present invention provide devices methods for sequencing DNA using arrays of reaction cavities containing sensors to monitor changes in solutions contained in the reaction cavities. Additional embodiments provide devices and methods for sequencing DNA using arrays of reaction cavities that allow for optical monitoring of solutions in the reaction cavities. Test and fill reaction schemes are disclosed that allow DNA to be sequenced. By sequencing DNA using parallel reactions contained in large arrays, DNA can be rapidly sequenced.
    Type: Grant
    Filed: September 13, 2005
    Date of Patent: May 26, 2015
    Assignee: INTEL CORPORATION
    Inventors: Tae-Woong Koo, Selena Chan, Xing Su, Zhang Jingwu, Mineo Yamakawa, Val M. Dubin
  • Publication number: 20150004628
    Abstract: Embodiments of the invention relate to integrated chemiluminescence devices and methods for monitoring molecular binding utilizing these devices and methods. These devices and methods can be used, for example, to identify antigen binding to antibodies. The devices include both a chemiluminescence material and a detector integrated together.
    Type: Application
    Filed: September 11, 2012
    Publication date: January 1, 2015
    Inventors: Narayan SUNDARARAJAN, Tae-Woong KOO
  • Patent number: 8852955
    Abstract: Provided herein are methods and systems for detecting biomolecular binding events using gigahertz or terahertz radiation. The methods and systems use low-energy spectroscopy to detect biomolecular binding events between molecules in an aqueous solution. The detected biomolecular binding events include, for example, nucleic acid hybridizations, antibody/antigen binding, and receptor/ligand binding.
    Type: Grant
    Filed: April 5, 2010
    Date of Patent: October 7, 2014
    Assignee: Intel Corporation
    Inventors: Tae-Woong Koo, Andrew Berlin, Ken Salsman, Brian Ostrovsky
  • Patent number: 8716833
    Abstract: A method of manufacturing a semiconductor device including forming on a substrate an insulating interlayer through which a capacitor contact is interposed; forming on the insulating interlayer a first upper electrode having an opening through which the capacitor contact is exposed; forming a first dielectric layer pattern on a lateral wall of the opening; forming a lower electrode on the first dielectric layer pattern formed in the opening and the capacitor contact; forming a second dielectric layer pattern on the lower electrode formed in the opening and the first dielectric layer pattern; and forming on the second dielectric layer pattern a second upper electrode so as to fill the opening and to contact the first upper electrode. The semiconductor device may prevent a lower electrode of a capacitor from collapsing.
    Type: Grant
    Filed: September 5, 2012
    Date of Patent: May 6, 2014
    Assignee: Samsung Electronics Co., Ltd.
    Inventor: Tae-woong Koo
  • Patent number: 8513002
    Abstract: Spectroscopic analysis systems and methods for analyzing samples are disclosed. An analysis system may contain an electromagnetic radiation source to provide radiation, a spectroscopic analysis chamber to perform a coherent Raman spectroscopy (e.g., stimulated Raman or coherent anti-Stokes Raman spectroscopy), and a radiation detector to detect radiation based on the spectroscopy. The chamber may have a resonant cavity to contain a sample for analysis, at least one window to the cavity to transmit the first radiation into the cavity and to transmit a second radiation out, a plurality of reflectors affixed to a housing of the cavity to reflect radiation of a predetermined frequency, the plurality of reflectors separated by a distance that is sufficient to resonate the radiation. The spectroscopic analysis system may be coupled with a nucleic acid sequencing system to receive a single nucleic acid derivative in solution and identify the derivative to sequence the nucleic acid.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: August 20, 2013
    Assignee: Intel Corporation
    Inventors: Andrew Arthur Berlin, Christopher Marc Gerth, Tae-Woong Koo
  • Publication number: 20130127012
    Abstract: A method of manufacturing a semiconductor device including forming on a substrate an insulating interlayer through which a capacitor contact is interposed; forming on the insulating interlayer a first upper electrode having an opening through which the capacitor contact is exposed; forming a first dielectric layer pattern on a lateral wall of the opening; forming a lower electrode on the first dielectric layer pattern formed in the opening and the capacitor contact; forming a second dielectric layer pattern on the lower electrode formed in the opening and the first dielectric layer pattern; and forming on the second dielectric layer pattern a second upper electrode so as to fill the opening and to contact the first upper electrode. The semiconductor device may prevent a lower electrode of a capacitor from collapsing.
    Type: Application
    Filed: September 5, 2012
    Publication date: May 23, 2013
    Applicant: Samsung Electronics Co., Ltd.
    Inventor: Tae-woong Koo
  • Patent number: 8288167
    Abstract: Embodiments of the invention relate to integrated chemiluminescence devices and methods for monitoring molecular binding utilizing these devices and methods. These devices and methods can be used, for example, to identify antigen binding to antibodies. The devices include both a chemiluminescence material and a detector integrated together.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: October 16, 2012
    Assignee: Intel Corporation
    Inventors: Narayan Sundararajan, Tae-Woong Koo
  • Publication number: 20120034686
    Abstract: Spectroscopic analysis systems and methods for analyzing samples are disclosed. An analysis system may contain an electromagnetic radiation source to provide radiation, a spectroscopic analysis chamber to perform a coherent Raman spectroscopy (e.g., stimulated Raman or coherent anti-Stokes Raman spectroscopy), and a radiation detector to detect radiation based on the spectroscopy. The chamber may have a resonant cavity to contain a sample for analysis, at least one window to the cavity to transmit the first radiation into the cavity and to transmit a second radiation out, a plurality of reflectors affixed to a housing of the cavity to reflect radiation of a predetermined frequency, the plurality of reflectors separated by a distance that is sufficient to resonate the radiation. The spectroscopic analysis system may be coupled with a nucleic acid sequencing system to receive a single nucleic acid derivative in solution and identify the derivative to sequence the nucleic acid.
    Type: Application
    Filed: August 29, 2011
    Publication date: February 9, 2012
    Inventors: Andrew Arthur Berlin, Christopher Marc Gerth, Tae-Woong Koo
  • Patent number: 8097421
    Abstract: The application relates to a method, system and device for performing biological assays. The method, system and device allow more accurate and specific detections of biomolecules in multiplex assays, such as immunoassays and DNA microarray assays. More specifically, the embodiments of the invention allow the detection of labels after their detachment or disassociation from a binding situation wherein interference from other labels or the background may reduce the accuracy of specificity of the detection. The embodiments of the invention further allow detection of individual labels.
    Type: Grant
    Filed: December 29, 2005
    Date of Patent: January 17, 2012
    Assignee: Intel Corporation
    Inventor: Tae-Woong Koo
  • Patent number: 8088628
    Abstract: Spectroscopic analysis systems and methods for analyzing samples are disclosed which exploit inelastically scattering radiation to amplify optical signals from an irradiated sample. Samples are irradiated in a chamber having a resonant cavity containing a plurality of affixed reflectors, where selective Stokes scattered radiation is transmitted to a detector for determination of sample identity. Coupling the spectroscopic analysis system and method with a nucleic acid sequencing system is also disclosed for determining nucleic acid sequences.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: January 3, 2012
    Assignee: Intel Corporation
    Inventors: Andrew Arthur Berlin, Christopher Marc Gerth, Tae-Woong Koo
  • Patent number: 8062841
    Abstract: Method and device to collect multiplex data simultaneously in analyte detection and analyze the data by experimentally trained software (machine-learning) is disclosed. Various ways (magnetic particles and microcoils) are disclosed to collect multiple reporter (tag) signals. Multiplex detection can increase the biomolecule analysis efficiency by using small sample size and saving assay reagents and time. Machine learning and data analysis schemes are also disclosed. Multiple affinity binding partners, each labeled by a unique reporter, are contacted with a sample and a single spectrum is taken to detect multiple reporter signals. The spectrum is deconvoluted by experimentally trained software to identify multiple analytes.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: November 22, 2011
    Assignee: Intel Corporation
    Inventors: Xing Su, Lei Sun, Mineo Yamakawa, Jingwu Zhang, Qing Ma, Tae-Woong Koo, Richard Jones
  • Publication number: 20110275144
    Abstract: Spectroscopic analysis systems and methods for analyzing samples are disclosed. An analysis system may contain an electromagnetic radiation source to provide radiation, a spectroscopic analysis chamber to perform a coherent Raman spectroscopy (e.g., stimulated Raman or coherent anti-Stokes Raman spectroscopy), and a radiation detector to detect radiation based on the spectroscopy. The chamber may have a resonant cavity to contain a sample for analysis, at least one window to the cavity to transmit the first radiation into the cavity and to transmit a second radiation out, a plurality of reflectors affixed to a housing of the cavity to reflect radiation of a predetermined frequency, the plurality of reflectors separated by a distance that is sufficient to resonate the radiation. The spectroscopic analysis system may be coupled with a nucleic acid sequencing system to receive a single nucleic acid derivative in solution and identify the derivative to sequence the nucleic acid.
    Type: Application
    Filed: July 19, 2011
    Publication date: November 10, 2011
    Inventors: Andrew Arthur BERLIN, Christopher Marc GERTH, Tae-Woong KOO
  • Patent number: 8009288
    Abstract: Spectroscopic analysis systems and methods for analyzing samples are disclosed. An analysis system may contain an electromagnetic radiation source to provide radiation, a spectroscopic analysis chamber to perform a coherent Raman spectroscopy (e.g., stimulated Raman or coherent anti-Stokes Raman spectroscopy), and a radiation detector to detect radiation based on the spectroscopy. The chamber may have a resonant cavity to contain a sample for analysis, at least one window to the cavity to transmit the first radiation into the cavity and to transmit a second radiation out, a plurality of reflectors affixed to a housing of the cavity to reflect radiation of a predetermined frequency, the plurality of reflectors separated by a distance that is sufficient to resonate the radiation. The spectroscopic analysis system may be coupled with a nucleic acid sequencing system to receive a single nucleic acid derivative in solution and identify the derivative to sequence the nucleic acid.
    Type: Grant
    Filed: April 14, 2006
    Date of Patent: August 30, 2011
    Assignee: Intel Corporation
    Inventors: Andrew Arthur Berlin, Christopher Marc Gerth, Tae-Woong Koo
  • Patent number: 7843562
    Abstract: The invention provides methods used to analyze the contents of a biological sample, such as blood serum, with cascade Raman sensing. A fluorescence producing nanoporous biosensor having probes that bind specifically to known analytes is contacted with a biological sample and one or more bound complexes coupled to the porous semiconductor structure are formed. The bound complexes are contacted with a Raman-active probe that binds specifically to the bound complexes and the biosensor is illuminated to generate fluorescent emissions from the biosensor. These fluorescent emissions generate Raman signals from the bound complexes. The Raman signals produced by the bound complexes are detected and the Raman signal associated with a bound protein-containing analyte is indicative of the presence of the protein-containing compound in the sample. The invention methods are useful to provide a protein profile of a patient sample. The invention also provides detection systems useful to practice the invention methods.
    Type: Grant
    Filed: February 1, 2007
    Date of Patent: November 30, 2010
    Assignee: Intel Corporation
    Inventors: Selena Chan, Tae-Woong Koo
  • Publication number: 20100278697
    Abstract: Provided herein are methods and systems for detecting biomolecular binding events using gigahertz or terahertz radiation. The methods and systems use low-energy spectroscopy to detect biomolecular binding events between molecules in an aqueous solution. The detected biomolecular binding events include, for example, nucleic acid hybridizations, antibody/antigen binding, and receptor/ligand binding.
    Type: Application
    Filed: April 5, 2010
    Publication date: November 4, 2010
    Inventors: Tae-Woong KOO, Andrew Berlin, Ken Salsman, Brian Ostrovsky
  • Publication number: 20100267013
    Abstract: The methods and apparatus disclosed herein concern nucleic acid sequencing by enhanced Raman spectroscopy. In certain embodiments of the invention, nucleotides are covalently attached to Raman labels before incorporation into a nucleic acid. In other embodiments, unlabeled nucleic acids are used. Exonuclease treatment of the nucleic acid results in the release of labeled or unlabeled nucleotides that are detected by Raman spectroscopy. In alternative embodiments of the invention, nucleotides released from a nucleic acid by exonuclease treatment are covalently cross-linked to nanoparticles and detected by surface enhanced Raman spectroscopy (SERS), surface enhanced resonance Raman spectroscopy (SERRS) and/or coherent anti-Stokes Raman spectroscopy (CARS). Other embodiments of the invention concern apparatus for nucleic acid sequencing.
    Type: Application
    Filed: May 24, 2007
    Publication date: October 21, 2010
    Applicant: INTEL CORPORATION
    Inventors: Xing Su, Andrew Arthur Berlin, Selena Chan, Steven J. Kirch, Tae-Woong Koo, Gabi Neubauer, Valluri Rao, Narayan Sundararajan, Mineo Yamakawa
  • Patent number: 7776547
    Abstract: Methods and apparatus are provided for assaying cell samples, which may be living cells, using probes labeled with composite organic-inorganic nanoparticles (COINs) and microspheres with COINs embedded within a polymer matrix to which the probe moiety is attached. COINs intrinsically produce SERS signals upon laser irradiation, making COIN-labeled probes particularly suitable in a variety of methods for assaying cells, including biological molecules that may be contained on or within cells, most of which are not inherently Raman-active. The invention provides variations of the sandwich immunoassay employing both specific and degenerate binding, methods for reverse phase assay of tissue samples and cell microstructures, in solution displacement and competition assays, and the like. Systems and chips useful for practicing the invention assays are also provided.
    Type: Grant
    Filed: December 30, 2004
    Date of Patent: August 17, 2010
    Assignee: Intel Corporation
    Inventors: Mark Roth, Andrew Berlin, Selena Chan, Tae-Woong Koo, Xing Su, Lei Sun
  • Publication number: 20100151454
    Abstract: Disclosed herein are methods, apparatuses, and systems for performing nucleic acid sequencing reactions and molecular binding reactions in a microfluidic channel. The methods, apparatuses, and systems can include a restriction barrier to restrict movement of a particle to which a nucleic acid is attached. Furthermore, the methods, apparatuses, and systems can include hydrodynamic focusing of a delivery flow. In addition, the methods, apparatuses, and systems can reduce non-specific interaction with a surface of the microfluidic channel by providing a protective flow between the surface and a delivery flow.
    Type: Application
    Filed: October 22, 2008
    Publication date: June 17, 2010
    Inventors: Narayanan Sundararajan, Lei Sun, Yuegang Zhang, Xing Su, Selena Chan, Tae-Woong Koo, Andrew A. Berlin